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- W3044932166 abstract "In the last two decades, microneedles (MNs) have received significant interest due to their potential for painless transdermal drug delivery (TDD) and minimal skin damage. MNs have found applications in a range of research and development areas in drug delivery. They have been prepared using a variety of materials and fabrication techniques resulting in MN arrays with different dimensions, shapes, and geometries for delivery of a variety of drug molecules. These parameters play crucial roles in determining the drug release profiles from the MNs. Developing mathematical modelling, simulation, and optimisation techniques is vital to achieving the desired MN performances. These will then be helpful for pharmaceutical and biotechnological industries as well as professionals working in the field of regulatory affairs focusing on MN based TDD systems. This is because modelling has a great potential to reduce the financial and time cost of both the MNs' studies and manufacturing. For example, a number of robust mathematical models for predicting the performance of the MNs in vivo have emerged recently which incorporate the roles of the structural and mechanical properties of the skin. In addressing these points, this review paper aims to highlight the current status of the MN modelling research, in particular, the modelling, simulation and optimisation of the systems for drug delivery. The theoretical basis for the simulation of MN enhanced diffusion is discussed within this paper. Thus, this review paper provides a better understanding of the modelling of the MN mediated drug delivery process." @default.
- W3044932166 created "2020-07-29" @default.
- W3044932166 creator A5004310377 @default.
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- W3044932166 creator A5082416350 @default.
- W3044932166 date "2020-07-22" @default.
- W3044932166 modified "2023-09-29" @default.
- W3044932166 title "Mathematical Modelling, Simulation and Optimisation of Microneedles for Transdermal Drug Delivery: Trends and Progress" @default.
- W3044932166 cites W1733359976 @default.
- W3044932166 cites W1964492247 @default.
- W3044932166 cites W1965470028 @default.
- W3044932166 cites W1965758660 @default.
- W3044932166 cites W1965852633 @default.
- W3044932166 cites W1966466925 @default.
- W3044932166 cites W1966643076 @default.
- W3044932166 cites W1969447336 @default.
- W3044932166 cites W1979494690 @default.
- W3044932166 cites W1979531314 @default.
- W3044932166 cites W1980923808 @default.
- W3044932166 cites W1985772998 @default.
- W3044932166 cites W1985838594 @default.
- W3044932166 cites W1986157072 @default.
- W3044932166 cites W1989224931 @default.
- W3044932166 cites W1989377946 @default.
- W3044932166 cites W1992843088 @default.
- W3044932166 cites W1999052497 @default.
- W3044932166 cites W1999058074 @default.
- W3044932166 cites W2001260338 @default.
- W3044932166 cites W2004964868 @default.
- W3044932166 cites W2006066267 @default.
- W3044932166 cites W2006241246 @default.
- W3044932166 cites W2006629406 @default.
- W3044932166 cites W2006749540 @default.
- W3044932166 cites W2007539416 @default.
- W3044932166 cites W2012917475 @default.
- W3044932166 cites W2013315584 @default.
- W3044932166 cites W2013868881 @default.
- W3044932166 cites W2022226757 @default.
- W3044932166 cites W2029584965 @default.
- W3044932166 cites W2030468727 @default.
- W3044932166 cites W2031524340 @default.
- W3044932166 cites W2038815967 @default.
- W3044932166 cites W2040900349 @default.
- W3044932166 cites W2043378065 @default.
- W3044932166 cites W2044233978 @default.
- W3044932166 cites W2048027001 @default.
- W3044932166 cites W2048388328 @default.
- W3044932166 cites W2049074302 @default.
- W3044932166 cites W2050207992 @default.
- W3044932166 cites W2053684065 @default.
- W3044932166 cites W2054294261 @default.
- W3044932166 cites W2061383087 @default.
- W3044932166 cites W2061958341 @default.
- W3044932166 cites W2062683657 @default.
- W3044932166 cites W2063026046 @default.
- W3044932166 cites W2070819648 @default.
- W3044932166 cites W2083710819 @default.
- W3044932166 cites W2085338797 @default.
- W3044932166 cites W2088893533 @default.
- W3044932166 cites W2089143024 @default.
- W3044932166 cites W2089721356 @default.
- W3044932166 cites W2090155464 @default.
- W3044932166 cites W2090299109 @default.
- W3044932166 cites W2091257316 @default.
- W3044932166 cites W2093014785 @default.
- W3044932166 cites W2096501414 @default.
- W3044932166 cites W2097023289 @default.
- W3044932166 cites W2106424445 @default.
- W3044932166 cites W2107499078 @default.
- W3044932166 cites W2112607718 @default.
- W3044932166 cites W2113792909 @default.
- W3044932166 cites W2122712791 @default.
- W3044932166 cites W2130849232 @default.
- W3044932166 cites W2132780556 @default.
- W3044932166 cites W2134241623 @default.
- W3044932166 cites W2134604428 @default.
- W3044932166 cites W2146794940 @default.
- W3044932166 cites W2147323866 @default.
- W3044932166 cites W2151576934 @default.
- W3044932166 cites W2154115666 @default.
- W3044932166 cites W2159403770 @default.
- W3044932166 cites W2164660172 @default.
- W3044932166 cites W2166140642 @default.
- W3044932166 cites W2169841193 @default.
- W3044932166 cites W2171506711 @default.
- W3044932166 cites W2327618122 @default.
- W3044932166 cites W2332567582 @default.
- W3044932166 cites W2335972983 @default.
- W3044932166 cites W2470696554 @default.
- W3044932166 cites W2472243521 @default.
- W3044932166 cites W2555741762 @default.
- W3044932166 cites W2565049509 @default.
- W3044932166 cites W2568860203 @default.
- W3044932166 cites W2577756259 @default.
- W3044932166 cites W2586950750 @default.
- W3044932166 cites W2588644411 @default.