FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045013669> ?p ?o ?g. }

• W3045013669 abstract "Background: Human immunodeficiency syndrome is a global pandemic and the advent of highly active antiretroviral therapy has changed the course of the disease from acute highly fatal disease to a treatable chronic form. As a result, the clinical sequelae of HIV infection are changing as patients live longer. The development of HIV increases the risk of developing pulmonary arterial hypertension compared to the general population. Furthermore, pulmonary arterial hypertension in HIV patients reduces their survival compared to HIV infected patients who do not have pulmonary arterial hypertension. Therefore there is need to study the condition in our environment to help us manage our patients better. Aim: This study assessed the prevalence of pulmonary hypertension and the pattern of left ventricular function in HIV infected treatment naive patients in Ahmadu Bello University Teaching Hospital, (ABUTH) Shika, Zaria, Kaduna State. Methodology: This was a hospital based descriptive cross sectional study designed to determine the prevalence of pulmonary arterial hypertension in HIV positive patients aged 18 years and above at ABUTH and age and sex-matched controls from August 2015 to January 2016. Ethical clearance and informed consent were obtained from the Health Research Ethical Committee (HREC) of ABUTH and subjects respectively. A structured questionnaire was completed for each successive participants and data was analysed using statistical package for social sciences (SPSS) version 17. Results were presented on tables and charts. Statistical significance was evaluated with chi square (χ2), and independent sample t-test at ρ value of <0.05. Relationship between continuous variables were determined using Pearson’s coefficient of correlation and linear regression. Results: One hundred and thirty (130) subjects consisting of equal number of patients and controls were studied. The mean age of patients and controls was 34.63±8.38 and 32.85±8.33 years respectively. Male and female patients were 29(44.6%) and 36(55.4%) while controls were, 34(52.3%) and 31(47.7%) respectively. There was no statistically significant difference between the mean age (ρ=0.226) and sex distribution (ρ=0.483) of patients and controls. The prevalence of pulmonary arterial hypertension among patients and controls was 9.2% and 1.5% respectively (p=0.052). The Left ventricular abnormalities seen were Left ventricular systolic dysfunction (13.8%) in patients and (0%) in controls, dilated cardiomyopathy (4.6%) in patients with none in the controls (p=0.001), and left ventricular diastolic dysfunction (30.8%) in the patients and (10.8) in the control (p=004). Pericardial effusion was seen in (18.5%) of the patients and in (4.6%) of the control (p=0.013). For the patients with pulmonary hypertension, the mean (± SD) of the right ventricular systolic pressure (RVSP) was 35.13 (± 3.92) mmHg versus 8.86(±7.08) mmHg in patients without pulmonary hypertension (p=0.0001). Conclusion: Cardiac abnormalities in HIV patients including pulmonary arterial hypertension are common in our environment and they can be present even in asymptomatic patients. Cardiac catheterization is the gold standard for definitive diagnosis of pulmonary hypertension however; noninvasive, not expensive and widely available echocardiography can be used as first line screening of patients to improve their risk stratification." @default.
• W3045013669 created "2020-07-29" @default.
• W3045013669 creator A5080142502 @default.
• W3045013669 date "2017-01-01" @default.
• W3045013669 modified "2023-09-27" @default.
• W3045013669 title "Assessment of Pulmonary Hypertension and Pattern of Left Ventricular Function among HAART Naive HIV Positive Adults in Ahmadu Bello University Teaching Hospital, Zaria" @default.
• W3045013669 hasPublicationYear "2017" @default.
• W3045013669 type Work @default.
• W3045013669 sameAs 3045013669 @default.
• W3045013669 citedByCount "0" @default.
• W3045013669 crossrefType "journal-article" @default.
• W3045013669 hasAuthorship W3045013669A5080142502 @default.
• W3045013669 hasConcept C126322002 @default.
• W3045013669 hasConcept C141071460 @default.
• W3045013669 hasConcept C142724271 @default.
• W3045013669 hasConcept C187212893 @default.
• W3045013669 hasConcept C204787440 @default.
• W3045013669 hasConcept C2780930700 @default.
• W3045013669 hasConcept C2908647359 @default.
• W3045013669 hasConcept C65409693 @default.
• W3045013669 hasConcept C68122502 @default.
• W3045013669 hasConcept C71924100 @default.
• W3045013669 hasConcept C99454951 @default.
• W3045013669 hasConceptScore W3045013669C126322002 @default.
• W3045013669 hasConceptScore W3045013669C141071460 @default.
• W3045013669 hasConceptScore W3045013669C142724271 @default.
• W3045013669 hasConceptScore W3045013669C187212893 @default.
• W3045013669 hasConceptScore W3045013669C204787440 @default.
• W3045013669 hasConceptScore W3045013669C2780930700 @default.
• W3045013669 hasConceptScore W3045013669C2908647359 @default.
• W3045013669 hasConceptScore W3045013669C65409693 @default.
• W3045013669 hasConceptScore W3045013669C68122502 @default.
• W3045013669 hasConceptScore W3045013669C71924100 @default.
• W3045013669 hasConceptScore W3045013669C99454951 @default.
• W3045013669 hasLocation W30450136691 @default.
• W3045013669 hasOpenAccess W3045013669 @default.
• W3045013669 hasPrimaryLocation W30450136691 @default.
• W3045013669 hasRelatedWork W2038593863 @default.
• W3045013669 hasRelatedWork W2042396858 @default.
• W3045013669 hasRelatedWork W2142436007 @default.
• W3045013669 hasRelatedWork W2351626603 @default.
• W3045013669 hasRelatedWork W2368334251 @default.
• W3045013669 hasRelatedWork W2382910006 @default.
• W3045013669 hasRelatedWork W2402355403 @default.
• W3045013669 hasRelatedWork W2426171490 @default.
• W3045013669 hasRelatedWork W2477601010 @default.
• W3045013669 hasRelatedWork W2510931451 @default.
• W3045013669 hasRelatedWork W2538956361 @default.
• W3045013669 hasRelatedWork W2787393703 @default.
• W3045013669 hasRelatedWork W2850956768 @default.
• W3045013669 hasRelatedWork W3032631810 @default.
• W3045013669 hasRelatedWork W3038028499 @default.
• W3045013669 hasRelatedWork W3044032920 @default.
• W3045013669 hasRelatedWork W3099774845 @default.
• W3045013669 hasRelatedWork W3124647713 @default.
• W3045013669 hasRelatedWork W3153799219 @default.
• W3045013669 hasRelatedWork W3169390135 @default.
• W3045013669 isParatext "false" @default.
• W3045013669 isRetracted "false" @default.
• W3045013669 magId "3045013669" @default.
• W3045013669 workType "article" @default.