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• W3045016883 abstract "PurposeInhomogeneities of the static magnetic B(_{0}) field are a major limiting factor in cardiac MRI at ultrahigh field (≥ 7T), as they result in signal loss and image distortions. Different magnetic susceptibilities of the myocardium and surrounding tissue in combination with cardiac motion lead to strong spatio‐temporal B(_{0})‐field inhomogeneities, and their homogenization (B0 shimming) is a prerequisite. Limitations of state‐of‐the‐art shimming are described, regional B(_{0}) variations are measured, and a methodology for spherical harmonics shimming of the B(_{0}) field within the human myocardium is proposed.MethodsThe spatial B(_{0})‐field distribution in the heart was analyzed as well as temporal B(_{0})‐field variations in the myocardium over the cardiac cycle. Different shim region‐of‐interest selections were compared, and hardware limitations of spherical harmonics B(_{0}) shimming were evaluated by calibration‐based B0‐field modeling. The role of third‐order spherical harmonics terms was analyzed as well as potential benefits from cardiac phase–specific shimming.ResultsThe strongest B(_{0})‐field inhomogeneities were observed in localized spots within the left‐ventricular and right‐ventricular myocardium and varied between systolic and diastolic cardiac phases. An anatomy‐driven shim region‐of‐interest selection allowed for improved B(_{0})‐field homogeneity compared with a standard shim region‐of‐interest cuboid. Third‐order spherical harmonics terms were demonstrated to be beneficial for shimming of these myocardial B(_{0})‐field inhomogeneities. Initial results from the in vivo implementation of a potential shim strategy were obtained. Simulated cardiac phase–specific shimming was performed, and a shim term‐by‐term analysis revealed periodic variations of required currents.ConclusionChallenges in state‐of‐the‐art B(_{0}) shimming of the human heart at 7 T were described. Cardiac phase–specific shimming strategies were found to be superior to vendor‐supplied shimming." @default.
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• W3045016883 date "2020-07-23" @default.
• W3045016883 modified "2023-10-13" @default.
• W3045016883 title "B ₀ shimming of the human heart at 7T" @default.
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• W3045016883 doi "https://doi.org/10.1002/mrm.28423" @default.
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