FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045076672> ?p ?o ?g. }

• W3045076672 endingPage "121" @default.
• W3045076672 startingPage "110" @default.
• W3045076672 abstract "<b><i>Introduction:</i></b> Genomic tests can predict risk and tailor screening recommendations for colorectal cancer (CRC). Primary care could be suitable for their widespread implementation. <b><i>Objective:</i></b> We aimed to assess the feasibility and acceptability of administering a CRC genomic test in primary care. <b><i>Methods:</i></b> Participants aged 45–74 years recruited from 4 Australian general practices were offered a genomic CRC risk test. Participants received brief verbal information about the test comprising 45 CRC-associated single-nucleotide polymorphisms, before choosing whether to undertake the test. Personalized risks were given to testers. Uptake and knowledge of the genomic test, cancer-specific anxiety (Cancer Worry Scale), psychosocial impact (Multidimensional Impact of Cancer Risk Assessment [MICRA] score), and impact on CRC screening behaviour within 6 months were measured. <b><i>Results:</i></b> In 150 participants, test uptake was high (126, 84%), with 125 (83%) having good knowledge of the genomic test. Moderate risk participants were impacted more by the test (MICRA mean: 15.9) than average risk participants (mean: 9.5, difference in means: 6.4, 95% confidence interval (CI): 1.5, 11.2, <i>p</i> = 0.01), but all scores were low. Average risk participants’ cancer-specific anxiety decreased (mean differences from baseline: 1 month −0.5, 95% CI: −1.0, −0.1, <i>p</i> = 0.03; 6 months −0.6, 95% CI: −1.0, −0.2, <i>p</i> = 0.01). We found limited evidence for genomic testers being more likely to complete the risk-appropriate CRC screening than non-testers (41 vs. 17%, odds ratio = 3.4, 95% CI: 0.6, 34.8, <i>p</i> = 0.19), but some mediators of screening behaviour were altered in genomic testers. <b><i>Conclusions:</i></b> Genomic testing for CRC risk in primary care is acceptable and likely feasible. Further development of the risk assessment intervention could strengthen the impact on screening behaviour." @default.
• W3045076672 created "2020-07-29" @default.
• W3045076672 creator A5002349630 @default.
• W3045076672 creator A5013112656 @default.
• W3045076672 creator A5019702967 @default.
• W3045076672 creator A5042549176 @default.
• W3045076672 creator A5051077025 @default.
• W3045076672 creator A5051440329 @default.
• W3045076672 creator A5069535362 @default.
• W3045076672 creator A5069713035 @default.
• W3045076672 creator A5076928530 @default.
• W3045076672 creator A5080895008 @default.
• W3045076672 date "2020-01-01" @default.
• W3045076672 modified "2023-09-25" @default.
• W3045076672 title "A Genomic Test for Colorectal Cancer Risk: Is This Acceptable and Feasible in Primary Care?" @default.
• W3045076672 cites W1521660172 @default.
• W3045076672 cites W1876964634 @default.
• W3045076672 cites W1979774047 @default.
• W3045076672 cites W1982577230 @default.
• W3045076672 cites W1983777759 @default.
• W3045076672 cites W1990141326 @default.
• W3045076672 cites W1990725932 @default.
• W3045076672 cites W1994277526 @default.
• W3045076672 cites W2001913342 @default.
• W3045076672 cites W2021542248 @default.
• W3045076672 cites W2033256829 @default.
• W3045076672 cites W2062098118 @default.
• W3045076672 cites W2073224124 @default.
• W3045076672 cites W2089051328 @default.
• W3045076672 cites W2106832044 @default.
• W3045076672 cites W2131101814 @default.
• W3045076672 cites W2134831355 @default.
• W3045076672 cites W2170271912 @default.
• W3045076672 cites W2178776789 @default.
• W3045076672 cites W2261128770 @default.
• W3045076672 cites W2261966018 @default.
• W3045076672 cites W2299533639 @default.
• W3045076672 cites W2345958530 @default.
• W3045076672 cites W2528514103 @default.
• W3045076672 cites W2542706309 @default.
• W3045076672 cites W2582326349 @default.
• W3045076672 cites W2589956389 @default.
• W3045076672 cites W2615321036 @default.
• W3045076672 cites W2802221886 @default.
• W3045076672 cites W2803033422 @default.
• W3045076672 cites W2890607451 @default.
• W3045076672 cites W2898585855 @default.
• W3045076672 cites W2949199469 @default.
• W3045076672 cites W2990380277 @default.
• W3045076672 cites W4250942059 @default.
• W3045076672 doi "https://doi.org/10.1159/000508963" @default.
• W3045076672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32688362" @default.
• W3045076672 hasPublicationYear "2020" @default.
• W3045076672 type Work @default.
• W3045076672 sameAs 3045076672 @default.
• W3045076672 citedByCount "11" @default.
• W3045076672 countsByYear W30450766722021 @default.
• W3045076672 countsByYear W30450766722022 @default.
• W3045076672 countsByYear W30450766722023 @default.
• W3045076672 crossrefType "journal-article" @default.
• W3045076672 hasAuthorship W3045076672A5002349630 @default.
• W3045076672 hasAuthorship W3045076672A5013112656 @default.
• W3045076672 hasAuthorship W3045076672A5019702967 @default.
• W3045076672 hasAuthorship W3045076672A5042549176 @default.
• W3045076672 hasAuthorship W3045076672A5051077025 @default.
• W3045076672 hasAuthorship W3045076672A5051440329 @default.
• W3045076672 hasAuthorship W3045076672A5069535362 @default.
• W3045076672 hasAuthorship W3045076672A5069713035 @default.
• W3045076672 hasAuthorship W3045076672A5076928530 @default.
• W3045076672 hasAuthorship W3045076672A5080895008 @default.
• W3045076672 hasConcept C118552586 @default.
• W3045076672 hasConcept C121608353 @default.
• W3045076672 hasConcept C126322002 @default.
• W3045076672 hasConcept C143998085 @default.
• W3045076672 hasConcept C150966472 @default.
• W3045076672 hasConcept C151730666 @default.
• W3045076672 hasConcept C2777267654 @default.
• W3045076672 hasConcept C2779978724 @default.
• W3045076672 hasConcept C44249647 @default.
• W3045076672 hasConcept C526805850 @default.
• W3045076672 hasConcept C558461103 @default.
• W3045076672 hasConcept C71924100 @default.
• W3045076672 hasConcept C86803240 @default.
• W3045076672 hasConceptScore W3045076672C118552586 @default.
• W3045076672 hasConceptScore W3045076672C121608353 @default.
• W3045076672 hasConceptScore W3045076672C126322002 @default.
• W3045076672 hasConceptScore W3045076672C143998085 @default.
• W3045076672 hasConceptScore W3045076672C150966472 @default.
• W3045076672 hasConceptScore W3045076672C151730666 @default.
• W3045076672 hasConceptScore W3045076672C2777267654 @default.
• W3045076672 hasConceptScore W3045076672C2779978724 @default.
• W3045076672 hasConceptScore W3045076672C44249647 @default.
• W3045076672 hasConceptScore W3045076672C526805850 @default.
• W3045076672 hasConceptScore W3045076672C558461103 @default.
• W3045076672 hasConceptScore W3045076672C71924100 @default.
• W3045076672 hasConceptScore W3045076672C86803240 @default.
• W3045076672 hasIssue "3-4" @default.
• W3045076672 hasLocation W30450766721 @default.

• next