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- W3045265575 abstract "A multifunctional nanodrug, PAMAM@CuS-HA-RB/DOX, was prepared for the real time tracking and chemo-photothermal therapy of tumor cells. The CuS nanoclusters with diameter less than 10[Formula: see text]nm could be easily ingested by tumor cells and showed good colloid stability and high photothermal conversion efficiency. The hyaluronic acid (HA) coating and rhodamine B (RB) labeling endowed the nanocomposite with low cytotoxity and real time fluorescence imaging ability. In the acidic tumor microenvironment, the doxorubicin linked via the pH-responsive hydrazone bonds was released and worked synergistically with CuS to kill the tumor cells, which showed a high chemo-photothermal therapy capacity. All these properties indicated the PAMAM@CuS-HA-RB/DOX have promising application for the therapy of cancers and tracking of nanodrugs." @default.
- W3045265575 created "2020-07-29" @default.
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- W3045265575 date "2020-09-01" @default.
- W3045265575 modified "2023-10-16" @default.
- W3045265575 title "Fabrication of Small Multifunctional CuS Nanoclusters for Fluorescence Imaging and Chemo-Photothermal Therapy of Cancer" @default.
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- W3045265575 doi "https://doi.org/10.1142/s1793292020501234" @default.
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