FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045412060> ?p ?o ?g. }

• W3045412060 abstract "Background: Mastectomy, a procedure with high pain stimulation, is the treatment of choice for bitches with breast cancer. Tumescent anaesthesia is widely used for transoperative and postoperative analgesia in bitches submitted to mastectomy, because facilitates tissue divulsion, also contributing significantly for the rapid recovery of patients. Although, there is no consensus as to which local anesthetic to use and at what concentration it should be used. Herein was investigated which local anesthetics, lidocaine or ropivacaine, when used in tumescent solutions, could provide a more lasting analgesic effect in the postoperative period in bitches submitted to radical unilateral mastectomy.Materials, Methods & Results: Sixteen bitches were sedated with chlorpromazine (0.3 mg/kg) and meperidine (3 mg/kg) followed by anesthesia with propofol and isofluorane. Then, bitches were randomly assigned to two groups (n= 8 each): LG group, infused with 15 mL/kg of tumescence solution containing 0.1% lidocaine; and RG group, infused with 15 mL/kg of tumescence solution with 0.1% ropivacaine. The study was conducted in a double-blind fashion. Control group did not include, because the patients would be submitted to severe or unbearable pain, according to the short-form of the Glasgow pain Scale (CMPS-SF). The heart (HR) and respiratory (ƒ) rates, and systolic blood pressure (SBP) were measured in the pre-operative period and immediately after extubation (Mextub) and at 0.5 h, 1 h, 2 h, 4 h, 8 h, and 12 h after the extubation. Analgesic efficacy was assessed using the CMPS-SF and von Frey filaments. Both groups showed higher means for HR at 0.5 h (167 ± 7 in LG; 170 ± 7 in RG) than at 4 h (117 ± 7 in LG; 120 ± 7 in RG). CMPS-SF revealed higher medians (P= 0.038) at the Mextub and 12 h time points for the LG [5 (3-6) and 1 (0-2)] than for the RG [5 (2-5) and 0 (0-1)].Discussion: Pain was excluded as a possible explanation for the difference presented for HR in both groups because, moderate pain is considered when more than two cardiorespiratory parameters show an increase of at least 20% in relation to baseline values, which did not occur in this study. Indeed, most animals were walking at 0.5 h after extubation and, in many cases, this occurred before the collection of data for the postoperative period. This may have influenced the results since exercise releases catecholamines and increases HR. Moreover at 4 h after extubation, most animals were asleep. As metabolism decreases during sleep, expected that HR would also decrease and that was indeed the case. Regarding CMPS-SF, the way the patients walks was the item that most contributed to the high score found for the Mextub time point because it's impossible to be performed seconds after extubation. As the reluctance to move occurred only immediately after extubation, the values obtained at the Mextub time point are more likely to be due to an anesthetic residual effect and not to the pain stimulus itself. When the groups were compared, the median values obtained at the LG were greater than RG at the Mextub and 12 h postoperative time points. There was no need for analgesic rescue differing from those in literature that reported the need for analgesic rescue in 50% of the animals. Those study established a CMPS-SF score of 3.3 as indicative for analgesic rescue whereas our research established a score of 7. Tumescence solutions with lidocaine or ropivacaine provide equivalent postoperative analgesia for at least 12 h." @default.
• W3045412060 created "2020-07-29" @default.
• W3045412060 creator A5003943294 @default.
• W3045412060 creator A5020849971 @default.
• W3045412060 creator A5038306998 @default.
• W3045412060 creator A5046162965 @default.
• W3045412060 creator A5058180207 @default.
• W3045412060 creator A5070571104 @default.
• W3045412060 creator A5086517631 @default.
• W3045412060 creator A5087895411 @default.
• W3045412060 date "2020-01-23" @default.
• W3045412060 modified "2023-10-18" @default.
• W3045412060 title "Postoperative Analgesia Time in Dogs Submitted to Mastectomy and Anesthetized with Tumescent Solutions of Lidocaine or Ropivacaine" @default.
• W3045412060 cites W1982822755 @default.
• W3045412060 cites W2015162968 @default.
• W3045412060 cites W2033292657 @default.
• W3045412060 cites W2052843858 @default.
• W3045412060 cites W2094512616 @default.
• W3045412060 cites W2136218388 @default.
• W3045412060 cites W2136260865 @default.
• W3045412060 cites W2139730202 @default.
• W3045412060 cites W2608129466 @default.
• W3045412060 cites W2765360460 @default.
• W3045412060 cites W2804554037 @default.
• W3045412060 cites W2935767841 @default.
• W3045412060 cites W35158815 @default.
• W3045412060 doi "https://doi.org/10.22456/1679-9216.102649" @default.
• W3045412060 hasPublicationYear "2020" @default.
• W3045412060 type Work @default.
• W3045412060 sameAs 3045412060 @default.
• W3045412060 citedByCount "1" @default.
• W3045412060 countsByYear W30454120602023 @default.
• W3045412060 crossrefType "journal-article" @default.
• W3045412060 hasAuthorship W3045412060A5003943294 @default.
• W3045412060 hasAuthorship W3045412060A5020849971 @default.
• W3045412060 hasAuthorship W3045412060A5038306998 @default.
• W3045412060 hasAuthorship W3045412060A5046162965 @default.
• W3045412060 hasAuthorship W3045412060A5058180207 @default.
• W3045412060 hasAuthorship W3045412060A5070571104 @default.
• W3045412060 hasAuthorship W3045412060A5086517631 @default.
• W3045412060 hasAuthorship W3045412060A5087895411 @default.
• W3045412060 hasBestOaLocation W30454120601 @default.
• W3045412060 hasConcept C121608353 @default.
• W3045412060 hasConcept C126322002 @default.
• W3045412060 hasConcept C141071460 @default.
• W3045412060 hasConcept C2776277131 @default.
• W3045412060 hasConcept C2776359302 @default.
• W3045412060 hasConcept C2776918371 @default.
• W3045412060 hasConcept C2777757722 @default.
• W3045412060 hasConcept C2778162923 @default.
• W3045412060 hasConcept C2778994108 @default.
• W3045412060 hasConcept C2779929075 @default.
• W3045412060 hasConcept C2780149897 @default.
• W3045412060 hasConcept C2780269707 @default.
• W3045412060 hasConcept C2780820201 @default.
• W3045412060 hasConcept C42219234 @default.
• W3045412060 hasConcept C530470458 @default.
• W3045412060 hasConcept C71924100 @default.
• W3045412060 hasConceptScore W3045412060C121608353 @default.
• W3045412060 hasConceptScore W3045412060C126322002 @default.
• W3045412060 hasConceptScore W3045412060C141071460 @default.
• W3045412060 hasConceptScore W3045412060C2776277131 @default.
• W3045412060 hasConceptScore W3045412060C2776359302 @default.
• W3045412060 hasConceptScore W3045412060C2776918371 @default.
• W3045412060 hasConceptScore W3045412060C2777757722 @default.
• W3045412060 hasConceptScore W3045412060C2778162923 @default.
• W3045412060 hasConceptScore W3045412060C2778994108 @default.
• W3045412060 hasConceptScore W3045412060C2779929075 @default.
• W3045412060 hasConceptScore W3045412060C2780149897 @default.
• W3045412060 hasConceptScore W3045412060C2780269707 @default.
• W3045412060 hasConceptScore W3045412060C2780820201 @default.
• W3045412060 hasConceptScore W3045412060C42219234 @default.
• W3045412060 hasConceptScore W3045412060C530470458 @default.
• W3045412060 hasConceptScore W3045412060C71924100 @default.
• W3045412060 hasLocation W30454120601 @default.
• W3045412060 hasOpenAccess W3045412060 @default.
• W3045412060 hasPrimaryLocation W30454120601 @default.
• W3045412060 hasRelatedWork W1606388396 @default.
• W3045412060 hasRelatedWork W1991954839 @default.
• W3045412060 hasRelatedWork W2312497471 @default.
• W3045412060 hasRelatedWork W2358587172 @default.
• W3045412060 hasRelatedWork W2382542945 @default.
• W3045412060 hasRelatedWork W2464927715 @default.
• W3045412060 hasRelatedWork W2732148188 @default.
• W3045412060 hasRelatedWork W3130731338 @default.
• W3045412060 hasRelatedWork W4231547118 @default.
• W3045412060 hasRelatedWork W2186544327 @default.
• W3045412060 hasVolume "48" @default.
• W3045412060 isParatext "false" @default.
• W3045412060 isRetracted "false" @default.
• W3045412060 magId "3045412060" @default.
• W3045412060 workType "article" @default.