FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045448070> ?p ?o ?g. }

• W3045448070 abstract "Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with a new microbiome profile established in Chinese immigrants, which fails to prime the immune system. Here, we investigated how differences in composition of oropharyngeal microbiome may contribute to patterns of interaction between the microbiome and immune system in Chinese immigrants living in Australia.We recruited 44 adult Chinese immigrants: newly-arrived (n = 22, living in Australia < 6 months) and long-term Chinese immigrants (n = 22, living in Australia > 5 years), with age and gender matched. Oropharyngeal swabs, serum and whole blood were collected. The 16 s ribosomal RNA gene from the swabs was sequenced on the Illumina MiSeq platform. Innate immune responses were determined by 23 Toll-like receptors (TLR) pathway cytokines, while adaptive immune responses were determined by IgG-associated response to specific microbial/viral pathogens.The relative abundance of the genus Leptotrichia was higher in long-term immigrants as compared to that in newly-arrived Chinese immigrants, while the genus Deinococcus was significantly lower in long-term Chinese immigrants. The genera uncultured Lachnospiraceae, Erysipelotrichaceae UCG-007, Veillonella, and Actinomycetales_ambiguous taxa were negatively correlated with cytokine IL-6 in long-term Chinese immigrants (rho range: - 0.46 ~ - 0.73). With respect to adaptive immunity, several microbial taxa were significantly associated with IgG1 responsiveness to microbial antigens in long-term immigrants, while a significant correlation with IgG1 responsiveness to viral antigens was detected in newly-arrived immigrants.The composition of the oropharyngeal microbiome varies between newly-arrived and long-term Chinese immigrants. Specific microbial taxa are significantly associated with immunological parameters but with different association patterns between newly-arrived and long-term Chinese immigrants." @default.
• W3045448070 created "2020-07-29" @default.
• W3045448070 creator A5005014348 @default.
• W3045448070 creator A5017417512 @default.
• W3045448070 creator A5028467654 @default.
• W3045448070 creator A5036562505 @default.
• W3045448070 creator A5041041126 @default.
• W3045448070 creator A5057757181 @default.
• W3045448070 creator A5064891585 @default.
• W3045448070 creator A5084085789 @default.
• W3045448070 creator A5088197504 @default.
• W3045448070 date "2020-07-25" @default.
• W3045448070 modified "2023-10-15" @default.
• W3045448070 title "Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants" @default.
• W3045448070 cites W1536527549 @default.
• W3045448070 cites W1655860314 @default.
• W3045448070 cites W1715339469 @default.
• W3045448070 cites W1986685521 @default.
• W3045448070 cites W1995570039 @default.
• W3045448070 cites W2003988648 @default.
• W3045448070 cites W2026338038 @default.
• W3045448070 cites W2034313895 @default.
• W3045448070 cites W2035742252 @default.
• W3045448070 cites W2035935065 @default.
• W3045448070 cites W2038555213 @default.
• W3045448070 cites W2045174246 @default.
• W3045448070 cites W2046407144 @default.
• W3045448070 cites W2050591900 @default.
• W3045448070 cites W2072970694 @default.
• W3045448070 cites W2077553363 @default.
• W3045448070 cites W2084385377 @default.
• W3045448070 cites W2085818612 @default.
• W3045448070 cites W2086865963 @default.
• W3045448070 cites W2087292184 @default.
• W3045448070 cites W2090925778 @default.
• W3045448070 cites W2115225379 @default.
• W3045448070 cites W2124351063 @default.
• W3045448070 cites W2132548846 @default.
• W3045448070 cites W2133856765 @default.
• W3045448070 cites W2136879569 @default.
• W3045448070 cites W2147280137 @default.
• W3045448070 cites W2149505636 @default.
• W3045448070 cites W2157110918 @default.
• W3045448070 cites W2162437322 @default.
• W3045448070 cites W2212012451 @default.
• W3045448070 cites W2344609817 @default.
• W3045448070 cites W2601211966 @default.
• W3045448070 cites W2602842300 @default.
• W3045448070 cites W2613895329 @default.
• W3045448070 cites W2733928499 @default.
• W3045448070 cites W2776343058 @default.
• W3045448070 cites W2811147637 @default.
• W3045448070 cites W2968012609 @default.
• W3045448070 doi "https://doi.org/10.1186/s13223-020-00465-7" @default.
• W3045448070 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7491349" @default.
• W3045448070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32944027" @default.
• W3045448070 hasPublicationYear "2020" @default.
• W3045448070 type Work @default.
• W3045448070 sameAs 3045448070 @default.
• W3045448070 citedByCount "3" @default.
• W3045448070 countsByYear W30454480702021 @default.
• W3045448070 countsByYear W30454480702022 @default.
• W3045448070 countsByYear W30454480702023 @default.
• W3045448070 crossrefType "journal-article" @default.
• W3045448070 hasAuthorship W3045448070A5005014348 @default.
• W3045448070 hasAuthorship W3045448070A5017417512 @default.
• W3045448070 hasAuthorship W3045448070A5028467654 @default.
• W3045448070 hasAuthorship W3045448070A5036562505 @default.
• W3045448070 hasAuthorship W3045448070A5041041126 @default.
• W3045448070 hasAuthorship W3045448070A5057757181 @default.
• W3045448070 hasAuthorship W3045448070A5064891585 @default.
• W3045448070 hasAuthorship W3045448070A5084085789 @default.
• W3045448070 hasAuthorship W3045448070A5088197504 @default.
• W3045448070 hasBestOaLocation W30454480701 @default.
• W3045448070 hasConcept C143121216 @default.
• W3045448070 hasConcept C193419808 @default.
• W3045448070 hasConcept C203014093 @default.
• W3045448070 hasConcept C2779341262 @default.
• W3045448070 hasConcept C54355233 @default.
• W3045448070 hasConcept C86803240 @default.
• W3045448070 hasConcept C8891405 @default.
• W3045448070 hasConcept C89423630 @default.
• W3045448070 hasConceptScore W3045448070C143121216 @default.
• W3045448070 hasConceptScore W3045448070C193419808 @default.
• W3045448070 hasConceptScore W3045448070C203014093 @default.
• W3045448070 hasConceptScore W3045448070C2779341262 @default.
• W3045448070 hasConceptScore W3045448070C54355233 @default.
• W3045448070 hasConceptScore W3045448070C86803240 @default.
• W3045448070 hasConceptScore W3045448070C8891405 @default.
• W3045448070 hasConceptScore W3045448070C89423630 @default.
• W3045448070 hasIssue "1" @default.
• W3045448070 hasLocation W30454480701 @default.
• W3045448070 hasLocation W30454480702 @default.
• W3045448070 hasLocation W30454480703 @default.
• W3045448070 hasLocation W30454480704 @default.
• W3045448070 hasLocation W30454480705 @default.
• W3045448070 hasOpenAccess W3045448070 @default.
• W3045448070 hasPrimaryLocation W30454480701 @default.
• W3045448070 hasRelatedWork W1962483166 @default.
• W3045448070 hasRelatedWork W2087025979 @default.

• next