Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045455757> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W3045455757 abstract "Objective: The aim of this study was to investigate the normal changes that occur at the distal femoral epiphysis of rats and determine whether recurrent bouts of malaria altered them in anyway. Materials and Methods: The 1st phase of the study made use of 30 Sprague-Dawley rats aged 4 weeks. Two rats were culled each week for 15 weeks, the femoral bones of the rats were then harvested. Histological sections of the distal femora were prepared and studied. The 2nd phase involved 32 animals that were randomly assigned to four groups of 8 animals each. (Group A to D) Group A was given oral antimalarial drugs only, Group B was inoculated with Plasmodium berghei (NK65) only, Group C was inoculated with P. berghei (NK65) and treated with oral antimalarial drug, and Group D animals were neither inoculated nor given antimalarial drugs. At the end of the experiment histological sections of the femoral epiphysis of the rats were prepared and studied. Results: The microscopic architecture of the epiphyseal cartilage changed significantly as the animals aged. Significant differences were observed in mean bone thickness of the various experimental groups. There was however no significant difference in the mean cartilage thickness when comparison was made within the various groups. Conclusion: Although recurrent bouts of malaria infection appear not to alter the normal histological changes that occur in epiphyseal bone and cartilage layers, it most likely has an adverse effect on the rate of bone tissue deposition." @default.
- W3045455757 created "2020-07-29" @default.
- W3045455757 creator A5033423787 @default.
- W3045455757 creator A5036028772 @default.
- W3045455757 creator A5041807866 @default.
- W3045455757 creator A5057854020 @default.
- W3045455757 date "2020-01-01" @default.
- W3045455757 modified "2023-09-23" @default.
- W3045455757 title "The effect of recurrent malaria infections on bone and cartilage at the distal femoral epiphysis of rats: A histological study" @default.
- W3045455757 doi "https://doi.org/10.4103/jcrsm.jcrsm_11_20" @default.
- W3045455757 hasPublicationYear "2020" @default.
- W3045455757 type Work @default.
- W3045455757 sameAs 3045455757 @default.
- W3045455757 citedByCount "0" @default.
- W3045455757 crossrefType "journal-article" @default.
- W3045455757 hasAuthorship W3045455757A5033423787 @default.
- W3045455757 hasAuthorship W3045455757A5036028772 @default.
- W3045455757 hasAuthorship W3045455757A5041807866 @default.
- W3045455757 hasAuthorship W3045455757A5057854020 @default.
- W3045455757 hasBestOaLocation W30454557571 @default.
- W3045455757 hasConcept C105702510 @default.
- W3045455757 hasConcept C142724271 @default.
- W3045455757 hasConcept C2777237215 @default.
- W3045455757 hasConcept C2778048844 @default.
- W3045455757 hasConcept C2780472225 @default.
- W3045455757 hasConcept C2780550940 @default.
- W3045455757 hasConcept C57742111 @default.
- W3045455757 hasConcept C71924100 @default.
- W3045455757 hasConceptScore W3045455757C105702510 @default.
- W3045455757 hasConceptScore W3045455757C142724271 @default.
- W3045455757 hasConceptScore W3045455757C2777237215 @default.
- W3045455757 hasConceptScore W3045455757C2778048844 @default.
- W3045455757 hasConceptScore W3045455757C2780472225 @default.
- W3045455757 hasConceptScore W3045455757C2780550940 @default.
- W3045455757 hasConceptScore W3045455757C57742111 @default.
- W3045455757 hasConceptScore W3045455757C71924100 @default.
- W3045455757 hasLocation W30454557571 @default.
- W3045455757 hasOpenAccess W3045455757 @default.
- W3045455757 hasPrimaryLocation W30454557571 @default.
- W3045455757 hasRelatedWork W11853877 @default.
- W3045455757 hasRelatedWork W14890353 @default.
- W3045455757 hasRelatedWork W17297445 @default.
- W3045455757 hasRelatedWork W17369526 @default.
- W3045455757 hasRelatedWork W1745218 @default.
- W3045455757 hasRelatedWork W17558042 @default.
- W3045455757 hasRelatedWork W18455171 @default.
- W3045455757 hasRelatedWork W20570247 @default.
- W3045455757 hasRelatedWork W2686662 @default.
- W3045455757 hasRelatedWork W4255617 @default.
- W3045455757 isParatext "false" @default.
- W3045455757 isRetracted "false" @default.
- W3045455757 magId "3045455757" @default.
- W3045455757 workType "article" @default.