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- W3045473622 startingPage "103" @default.
- W3045473622 abstract "The subthalamic nucleus (STN) is a core basal ganglia structure involved in the control of motor, cognitive, motivational and affective functions. The (challenged) tripartite subdivision hypothesis places these functions into distinct sensorimotor, cognitive/associative, and limbic subregions based on the topography of cortical projections. To a large extent, this hypothesis is used to motivate the choice of target coordinates for implantation of deep brain stimulation electrodes for treatment of neurological and psychiatric disorders. Yet, the parallel organization of basal ganglia circuits has been known to allow considerable cross-talk, which might contribute to the occurrence of neuropsychiatric side effects when stimulating the dorsolateral, putative sensorimotor, part of the STN for treatment of Parkinson's disease. Any functional segregation within the STN is expected to be reflected both at micro-level microscopy and meso-level neural population activity. As such, we review the current empirical evidence from anterograde tracing and immunocytochemistry studies and from local field potential recordings for delineating the STN into distinct subregions. The spatial distribution of immunoreactivity presents as a combination of gradients, and although neural activity in distinct frequency bands appears spatially clustered, there is substantial overlap in peak locations. We argue that regional specialization without sharply defined borders is likely most representative of the STN's functional organization." @default.
- W3045473622 created "2020-07-29" @default.
- W3045473622 creator A5032945266 @default.
- W3045473622 creator A5033038536 @default.
- W3045473622 creator A5087594334 @default.
- W3045473622 date "2020-10-01" @default.
- W3045473622 modified "2023-10-05" @default.
- W3045473622 title "Functional segregation and integration within the human subthalamic nucleus from a micro- and meso-level perspective" @default.
- W3045473622 cites W1498617277 @default.
- W3045473622 cites W1501017967 @default.
- W3045473622 cites W1586135785 @default.
- W3045473622 cites W1926863470 @default.
- W3045473622 cites W193959434 @default.
- W3045473622 cites W1942197602 @default.
- W3045473622 cites W1958043126 @default.
- W3045473622 cites W1964673127 @default.
- W3045473622 cites W1965680082 @default.
- W3045473622 cites W1970994015 @default.
- W3045473622 cites W1973275441 @default.
- W3045473622 cites W1974745142 @default.
- W3045473622 cites W1977960199 @default.
- W3045473622 cites W1982827121 @default.
- W3045473622 cites W1983297775 @default.
- W3045473622 cites W1983413452 @default.
- W3045473622 cites W1985367358 @default.
- W3045473622 cites W1996815337 @default.
- W3045473622 cites W2000963066 @default.
- W3045473622 cites W2002043855 @default.
- W3045473622 cites W2002443895 @default.
- W3045473622 cites W2002785976 @default.
- W3045473622 cites W2005269174 @default.
- W3045473622 cites W2006414608 @default.
- W3045473622 cites W2009772699 @default.
- W3045473622 cites W2024921523 @default.
- W3045473622 cites W2027359963 @default.
- W3045473622 cites W2032337192 @default.
- W3045473622 cites W2034623206 @default.
- W3045473622 cites W2035999685 @default.
- W3045473622 cites W2043796909 @default.
- W3045473622 cites W2047471489 @default.
- W3045473622 cites W2057200630 @default.
- W3045473622 cites W2060588252 @default.
- W3045473622 cites W2063764383 @default.
- W3045473622 cites W2070178979 @default.
- W3045473622 cites W2070430616 @default.
- W3045473622 cites W2072977772 @default.
- W3045473622 cites W2073248892 @default.
- W3045473622 cites W2074191835 @default.
- W3045473622 cites W2075021671 @default.
- W3045473622 cites W2076183352 @default.
- W3045473622 cites W2077922441 @default.
- W3045473622 cites W2085753568 @default.
- W3045473622 cites W2086247534 @default.
- W3045473622 cites W2089209577 @default.
- W3045473622 cites W2091527263 @default.
- W3045473622 cites W2093909939 @default.
- W3045473622 cites W2096875305 @default.
- W3045473622 cites W2099779478 @default.
- W3045473622 cites W2101801005 @default.
- W3045473622 cites W2104822204 @default.
- W3045473622 cites W2107199167 @default.
- W3045473622 cites W2111624468 @default.
- W3045473622 cites W2124935025 @default.
- W3045473622 cites W2125684792 @default.
- W3045473622 cites W2127146698 @default.
- W3045473622 cites W2128472904 @default.
- W3045473622 cites W2138198377 @default.
- W3045473622 cites W2139874562 @default.
- W3045473622 cites W2140984685 @default.
- W3045473622 cites W2141716990 @default.
- W3045473622 cites W2141720176 @default.
- W3045473622 cites W2142625367 @default.
- W3045473622 cites W2147863265 @default.
- W3045473622 cites W2152069319 @default.
- W3045473622 cites W2155931363 @default.
- W3045473622 cites W2156743548 @default.
- W3045473622 cites W2161118302 @default.
- W3045473622 cites W2161130983 @default.
- W3045473622 cites W2163503262 @default.
- W3045473622 cites W2165267443 @default.
- W3045473622 cites W2167086554 @default.
- W3045473622 cites W2167683893 @default.
- W3045473622 cites W2206140810 @default.
- W3045473622 cites W2260876644 @default.
- W3045473622 cites W2310916568 @default.
- W3045473622 cites W2341482721 @default.
- W3045473622 cites W2388189391 @default.
- W3045473622 cites W2492247985 @default.
- W3045473622 cites W2515990420 @default.
- W3045473622 cites W2556015007 @default.
- W3045473622 cites W2589025904 @default.
- W3045473622 cites W2605334700 @default.
- W3045473622 cites W2734990562 @default.
- W3045473622 cites W2739238530 @default.
- W3045473622 cites W2764335780 @default.
- W3045473622 cites W2786806281 @default.
- W3045473622 cites W2789472639 @default.
- W3045473622 cites W2791533869 @default.