FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045496053> ?p ?o ?g. }

• W3045496053 abstract "Abstract Background Functional endoscopic sinus surgery (FESS) has been proposed as a selected treatment used in patients with chronic sinusitis that have not responded to medical therapy. Due to the nature of the location of endoscopic sinus surgery, even a small amount of bleeding can reduce the operative visibility. The aim of the work was to compare between dexmedetomidine and magnesium sulphate regarding their efficacy as a hypotensive agent in FESS in adult patients to obtain a bloodless surgical field. Patients and methods Sixty patients were randomly assigned into two groups, (D group) for dexmedetomidine ( n = 30) and (M group) for magnesium sulphate ( n = 30). In (D group), patients received 1 μg/kg dexmedetomidine in 100 ml saline solution as the loading dose 10 min before induction and 0.5–1 μg/kg/h infusion via syringe pump during surgery. In (M group), patients received 40 mg/kg magnesium sulphate in 100 ml saline solution over 10 min as the intravenous loading dose 10 min before induction, with a subsequent 10–15 mg/kg/h infusion. If there is an increase in the arterial blood pressure greater than the targeted MAP (55–65 mmHg), nitroglycerine infusion was started by 0.5 μg/kg/min. The surgeon estimated the quality of the surgical field and recorded it. The total blood loss was measured. In recovery, time to reach Aldrete score ≥ 9 was recorded to fulfill the discharge criteria. Pain score was assessed by the NRS numerical rating score. The time needed to first analgesia requirement was recorded. Sedation score was recorded using Ramsay sedation score. Results There was no statistically significant difference between both groups regarding MAP except at 30 min postoperatively as there was a statistically significant decrease in the MAP among the dexmedetomidine (D group) ( p = 0.039). Nitroglycerine was required in eight cases in the magnesium sulphate (M group) to reach the targeted MAP which was statistically significant compared to the (D group). Patients in the (D group) had a statistically significant decrease in heart rate than in the (M group) during and after the operation ( p = 0.35). The quality of the surgical field was significantly better among the (D group) ( p < 0.05), and accordingly, the surgeon satisfaction was significantly higher in the (D group) ( p = 0.001). Time to reach Aldrete score ≥ 9 and time for first analgesic requirement postoperatively were significantly longer in the (D group) ( p = 0.023, p = 0.001 respectively). Regarding the Ramsay sedation score (RSS), it was higher in the (D group) which was statistically significant ( p ≤ 0.001). Conclusion Dexmedetomidine was more effective than magnesium sulphate to achieve controlled hypotension in patients undergoing FESS. Compared with magnesium, dexmedetomidine offers the advantage of better clarity of the field, surgical satisfaction, less bleeding, and prolonged postoperative analgesia." @default.
• W3045496053 created "2020-08-03" @default.
• W3045496053 creator A5012341760 @default.
• W3045496053 creator A5031390825 @default.
• W3045496053 creator A5059105168 @default.
• W3045496053 creator A5085721921 @default.
• W3045496053 date "2020-07-28" @default.
• W3045496053 modified "2023-09-23" @default.
• W3045496053 title "Comparative study between magnesium sulphate and dexmedetomidine in controlled hypotension during functional endoscopic sinus surgery: a prospective randomized study" @default.
• W3045496053 cites W1427404698 @default.
• W3045496053 cites W16606683 @default.
• W3045496053 cites W1973798824 @default.
• W3045496053 cites W1978195515 @default.
• W3045496053 cites W1992407079 @default.
• W3045496053 cites W2005434131 @default.
• W3045496053 cites W2012398048 @default.
• W3045496053 cites W2023572761 @default.
• W3045496053 cites W2108105084 @default.
• W3045496053 cites W2116775674 @default.
• W3045496053 cites W2140905005 @default.
• W3045496053 cites W2146866257 @default.
• W3045496053 cites W2162917915 @default.
• W3045496053 cites W2181900193 @default.
• W3045496053 cites W2319529606 @default.
• W3045496053 cites W2329468116 @default.
• W3045496053 cites W2368187637 @default.
• W3045496053 cites W2527387421 @default.
• W3045496053 cites W2565115312 @default.
• W3045496053 cites W2614602963 @default.
• W3045496053 cites W2808941284 @default.
• W3045496053 cites W28935471 @default.
• W3045496053 cites W2904817141 @default.
• W3045496053 doi "https://doi.org/10.1186/s42077-020-00078-7" @default.
• W3045496053 hasPublicationYear "2020" @default.
• W3045496053 type Work @default.
• W3045496053 sameAs 3045496053 @default.
• W3045496053 citedByCount "1" @default.
• W3045496053 countsByYear W30454960532022 @default.
• W3045496053 crossrefType "journal-article" @default.
• W3045496053 hasAuthorship W3045496053A5012341760 @default.
• W3045496053 hasAuthorship W3045496053A5031390825 @default.
• W3045496053 hasAuthorship W3045496053A5059105168 @default.
• W3045496053 hasAuthorship W3045496053A5085721921 @default.
• W3045496053 hasBestOaLocation W30454960531 @default.
• W3045496053 hasConcept C126322002 @default.
• W3045496053 hasConcept C141071460 @default.
• W3045496053 hasConcept C191897082 @default.
• W3045496053 hasConcept C192562407 @default.
• W3045496053 hasConcept C2776187130 @default.
• W3045496053 hasConcept C2776452961 @default.
• W3045496053 hasConcept C2776814716 @default.
• W3045496053 hasConcept C2777397205 @default.
• W3045496053 hasConcept C2777768476 @default.
• W3045496053 hasConcept C2777953023 @default.
• W3045496053 hasConcept C2778117937 @default.
• W3045496053 hasConcept C2781302539 @default.
• W3045496053 hasConcept C2993524501 @default.
• W3045496053 hasConcept C35294091 @default.
• W3045496053 hasConcept C42219234 @default.
• W3045496053 hasConcept C543218039 @default.
• W3045496053 hasConcept C71924100 @default.
• W3045496053 hasConcept C84393581 @default.
• W3045496053 hasConceptScore W3045496053C126322002 @default.
• W3045496053 hasConceptScore W3045496053C141071460 @default.
• W3045496053 hasConceptScore W3045496053C191897082 @default.
• W3045496053 hasConceptScore W3045496053C192562407 @default.
• W3045496053 hasConceptScore W3045496053C2776187130 @default.
• W3045496053 hasConceptScore W3045496053C2776452961 @default.
• W3045496053 hasConceptScore W3045496053C2776814716 @default.
• W3045496053 hasConceptScore W3045496053C2777397205 @default.
• W3045496053 hasConceptScore W3045496053C2777768476 @default.
• W3045496053 hasConceptScore W3045496053C2777953023 @default.
• W3045496053 hasConceptScore W3045496053C2778117937 @default.
• W3045496053 hasConceptScore W3045496053C2781302539 @default.
• W3045496053 hasConceptScore W3045496053C2993524501 @default.
• W3045496053 hasConceptScore W3045496053C35294091 @default.
• W3045496053 hasConceptScore W3045496053C42219234 @default.
• W3045496053 hasConceptScore W3045496053C543218039 @default.
• W3045496053 hasConceptScore W3045496053C71924100 @default.
• W3045496053 hasConceptScore W3045496053C84393581 @default.
• W3045496053 hasIssue "1" @default.
• W3045496053 hasLocation W30454960531 @default.
• W3045496053 hasOpenAccess W3045496053 @default.
• W3045496053 hasPrimaryLocation W30454960531 @default.
• W3045496053 hasRelatedWork W2102280790 @default.
• W3045496053 hasRelatedWork W2368187637 @default.
• W3045496053 hasRelatedWork W2887453173 @default.
• W3045496053 hasRelatedWork W2990648701 @default.
• W3045496053 hasRelatedWork W3032262145 @default.
• W3045496053 hasRelatedWork W3032408341 @default.
• W3045496053 hasRelatedWork W3044626428 @default.
• W3045496053 hasRelatedWork W3045496053 @default.
• W3045496053 hasRelatedWork W4282840030 @default.
• W3045496053 hasRelatedWork W2555135375 @default.
• W3045496053 hasVolume "12" @default.
• W3045496053 isParatext "false" @default.
• W3045496053 isRetracted "false" @default.
• W3045496053 magId "3045496053" @default.
• W3045496053 workType "article" @default.