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• W3045549901 abstract "<h2>Abstract</h2><h3>Purpose</h3> We determined whether self-efficacy in seizure management differentially correlated with health-related quality of life (HRQoL) in persons with epilepsy depending on seizure recurrence and felt stigma. <h3>Methods</h3> This cross-sectional study was conducted in 312 adults with epilepsy. To determine which risk factors affected the benefits of self-efficacy for HRQoL, an analysis of covariance with an interaction term was used. The Quality of Life in Epilepsy Inventory-10 (QOLIE-10), the Epilepsy Self-Efficacy Scale (ESES), the Stigma Scale for Epilepsy (SS-E), and the Hospital Anxiety and Depression Scale (HADS) were assessed. <h3>Results</h3> QOLIE-10 scores positively correlated with ESES score and employed status, but negatively correlated with HADS scores, SS-E score ≥1, seizure frequency, and antiepileptic drug (AED) polytherapy. There were significant interaction effects between ESES score and 2-year seizure status (p = 0.025) or SS-E score ≥ 1 (p = 0.009) on QOLIE-10 scores. Self-efficacy in epilepsy management correlated with QOLIE-10 scores only in subjects that had experienced uncontrolled seizures (B = 0.090, p=0.003) or refractory seizures (B = 0.158, p=0.020) and in subjects with felt stigma (SS-E ≥ 1) (B = 0.183, p < 0.001). Contrastingly, generalized tonic-clonic seizure recurrence (p = 0.420), AED polytherapy (p = 0.667), depressive symptoms (p = 0.663), and anxiety (p = 0.503) did not interact with self-efficacy. <h3>Conclusions</h3> The relationship between epilepsy self-efficacy and overall HRQoL may differ depending on seizure recurrence and felt stigma. Our findings would be helpful for designing psychosocial interventions to improve HRQoL in persons with epilepsy." @default.
• W3045549901 created "2020-08-03" @default.
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• W3045549901 date "2020-10-01" @default.
• W3045549901 modified "2023-10-13" @default.
• W3045549901 title "Self-efficacy in seizure management differentially correlated with quality of life in persons with epilepsy depending on seizure recurrence and felt stigma" @default.
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• W3045549901 doi "https://doi.org/10.1016/j.seizure.2020.07.029" @default.
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