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• W30455979 abstract "BACKGROUND: This study estimates survival rates and its the main prognostic factors related, in women with breast cancer and submitted to local and systemic treatment in brazilian National Cancer Institute between 2001 to 2002.OBJECTIVES: The purpose of this study was to analyze five-year survival and the main prognostic factors among women with breast cancer diagnosed from 2001 to 2002 that had undergone surgical treatment in the Brazilian National Cancer Institute.MATERIAL AND METHODS: The survival curves were obtained in a hospital cohort of breast cancer with 1076 patients diagnosed and treated between 01/08/2001 and 01/12/2002, with median follow up time was 61 months (range 1 to 94 months) and mean patients age was 55, 9 years (standard deviation 13, 1). The Study variables were: age, marital status, tumor-related variables and the treatment-related variables. Survival functions were calculated by the Kaplan- Meier method.RESULTS: Among all patients, 23% performed neoadjuvant chemotherapy, 3% performed neoadjuvant hormone therapy and 2% performed neoadjuvant radiotherapy. A mastectomy was performed in 65%. In 84% of cases, lymphadenectomy was performed at the axillary level III with an average of 17 lymph nodes removed (SD 6. 40) and 46% had positive lymph nodes. Most had advanced pathological stage (57% II and 23% III) and 86% were ductal carcinoma infiltrante. O adjuvant treatment with chemotherapy was performed in 59%, the adjuvant radiotherapy performed in 63% and adjuvant hormone therapy in 68%. Patients were followed for a median 61 months (1-94), 16% of deaths occurred in the period, with average survival time of 82 months (95% CI 81-84) (Figure 1). In Kaplan-Meier analysis, the variables that were statistically associated with better overall survival were initial staging (p <0. 000), negative lymph nodes (p <0. 000), tumor size (p <0. 000), number of lymph nodes removed (p=0. 005), adjuvant chemotherapy (p = 0. 013) and neo-adjuvant (p <0. 000), adjuvant hormone therapy (p = 0. 001), CDI (p = 0. 005), conservative surgery (p <0. 000).CONCLUSION: Overall survival is similar to data found in the literature for staging. The results suggest the need for early diagnosis and treatment." @default.
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• W30455979 date "2012-10-10" @default.
• W30455979 modified "2023-09-27" @default.
• W30455979 title "Breast Cancer Survival Rate in a Cohort of Patients Treated in Brazilian National Cancer Institute in Rio de Janeiro, Brazil" @default.
• W30455979 doi "https://doi.org/10.7170/jsis.v1i3.421" @default.
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