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• W3045703075 endingPage "20201135" @default.
• W3045703075 startingPage "20201135" @default.
• W3045703075 abstract "Tardigrades have a miniaturized body plan. Miniaturization in tardigrades is associated with the loss of several organ systems and an intermediate region of their anteroposterior (AP) axis. However, how miniaturization has affected tardigrade legs is unclear. In arthropods and in onychophorans, the leg gap genes are expressed in regionalized proximodistal (PD) patterns in the legs. Functional studies indicate that these genes regulate growth in their respective expression domains and establish PD identities, partly through mutually antagonistic regulatory interactions. Here, we investigated the expression patterns of tardigrade orthologs of the leg gap genes. Rather than being restricted to a proximal leg region, as in arthropods and onychophorans, we detected coexpression of orthologues of homothorax and extradenticle broadly across the legs of the first three trunk segments in the tardigrade Hypsibius exemplaris . We could not identify a dachshund orthologue in tardigrade genomes, a gene that is expressed in an intermediate region of developing legs in arthropods and onychophorans, suggesting that this gene was lost in the tardigrade lineage. We detected Distal-less expression broadly across all developing leg buds in H. exemplaris embryos, unlike in arthropods and onychophorans, in which it exhibits a distally restricted expression domain. The broad expression patterns of the remaining leg gap genes in H. exemplaris legs may reflect the loss of dachshund and the accompanying loss of an intermediate region of the legs in the tardigrade lineage. We propose that the loss of intermediate regions of both the AP and PD body axes contributed to miniaturization of Tardigrada." @default.
• W3045703075 created "2020-08-03" @default.
• W3045703075 creator A5014596680 @default.
• W3045703075 creator A5048227336 @default.
• W3045703075 date "2020-07-29" @default.
• W3045703075 modified "2023-10-06" @default.
• W3045703075 title "Loss of intermediate regions of perpendicular body axes contributed to miniaturization of tardigrades" @default.
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• W3045703075 cites W1860355084 @default.
• W3045703075 cites W1912332738 @default.
• W3045703075 cites W1963957860 @default.
• W3045703075 cites W1973250306 @default.
• W3045703075 cites W1975391522 @default.
• W3045703075 cites W1976642158 @default.
• W3045703075 cites W1977802224 @default.
• W3045703075 cites W1983278083 @default.
• W3045703075 cites W1985797419 @default.
• W3045703075 cites W1991825130 @default.
• W3045703075 cites W1998020029 @default.
• W3045703075 cites W2001728721 @default.
• W3045703075 cites W2006091517 @default.
• W3045703075 cites W2010777779 @default.
• W3045703075 cites W2017493223 @default.
• W3045703075 cites W2017519756 @default.
• W3045703075 cites W2022104398 @default.
• W3045703075 cites W2028931722 @default.
• W3045703075 cites W2031900878 @default.
• W3045703075 cites W2034452566 @default.
• W3045703075 cites W2038945722 @default.
• W3045703075 cites W2039594253 @default.
• W3045703075 cites W2039773917 @default.
• W3045703075 cites W2040279322 @default.
• W3045703075 cites W2045151895 @default.
• W3045703075 cites W2049669496 @default.
• W3045703075 cites W2049682799 @default.
• W3045703075 cites W2053107012 @default.
• W3045703075 cites W2054964888 @default.
• W3045703075 cites W2056065988 @default.
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• W3045703075 cites W2070846434 @default.
• W3045703075 cites W2073838206 @default.
• W3045703075 cites W2079495531 @default.
• W3045703075 cites W2089526165 @default.
• W3045703075 cites W2095830907 @default.
• W3045703075 cites W2096413798 @default.
• W3045703075 cites W2099235342 @default.
• W3045703075 cites W2103583482 @default.
• W3045703075 cites W2108731933 @default.
• W3045703075 cites W2111211467 @default.
• W3045703075 cites W2114269159 @default.
• W3045703075 cites W2120627597 @default.
• W3045703075 cites W2129576088 @default.
• W3045703075 cites W2131042531 @default.
• W3045703075 cites W2132926880 @default.
• W3045703075 cites W2142848041 @default.
• W3045703075 cites W2143432174 @default.
• W3045703075 cites W2144267063 @default.
• W3045703075 cites W2151811187 @default.
• W3045703075 cites W2153148073 @default.
• W3045703075 cites W2156181563 @default.
• W3045703075 cites W2164350469 @default.
• W3045703075 cites W2168151871 @default.
• W3045703075 cites W2168495323 @default.
• W3045703075 cites W2174979248 @default.
• W3045703075 cites W2181738773 @default.
• W3045703075 cites W2204533759 @default.
• W3045703075 cites W2234962357 @default.
• W3045703075 cites W2267401506 @default.
• W3045703075 cites W2547342446 @default.
• W3045703075 cites W2559191318 @default.
• W3045703075 cites W2562167985 @default.
• W3045703075 cites W2586737773 @default.
• W3045703075 cites W2603180017 @default.
• W3045703075 cites W2610994034 @default.
• W3045703075 cites W2744149695 @default.
• W3045703075 cites W2885947426 @default.
• W3045703075 cites W2898892386 @default.
• W3045703075 cites W2899274547 @default.
• W3045703075 cites W2902405826 @default.
• W3045703075 cites W2952675130 @default.
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• W3045703075 doi "https://doi.org/10.1098/rspb.2020.1135" @default.
• W3045703075 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7423659" @default.
• W3045703075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33043863" @default.
• W3045703075 hasPublicationYear "2020" @default.
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