Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045761520> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W3045761520 endingPage "3249" @default.
- W3045761520 startingPage "3243" @default.
- W3045761520 abstract "We characterized linear growth in infants and children with X-linked hypophosphatemia (XLH).Provide linear growth curves for children with XLH from birth to early adolescence.Data from 4 prior studies of XLH were pooled to construct growth curves. UX023-CL002 was an observational, retrospective chart review. Pretreatment data were collected from 3 interventional trials: two phase 2 trials (UX023-CL201, UX023-CL205) and a phase 3 trial (UX023-CL301).Medical centers with expertise in treating XLH.Children with XLH, 1-14 years of age.None.Height-for-age linear growth curves, including values for the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles for children with XLH compared to population norms.A total of 228 patients (132 girls, 96 boys) with 2381 height measurements were included. Nearly all subjects (> 99%) reported prior management with supplementation therapy. Compared to the Center for Disease Control and Prevention growth curves, boys at age 3 months, 6 months, 9 months, 1 year, and 2 years had median height percentiles of 46%, 37%, 26%, 18%, and 5%, respectively; for girls the median height percentiles were 52%, 37%, 25%, 18%, and 7%, respectively. Annual growth in children with XLH fell below that of healthy children near 1 year of age and progressively declined during early childhood, with all median height percentiles < 8% between 2 and 12 years old.Children with XLH show decreased height gain by 1 year of age and remain below population norms thereafter. These data will help evaluate therapeutic interventions on linear growth for pediatric XLH." @default.
- W3045761520 created "2020-08-03" @default.
- W3045761520 creator A5006764055 @default.
- W3045761520 creator A5029181443 @default.
- W3045761520 creator A5034334789 @default.
- W3045761520 creator A5036775753 @default.
- W3045761520 creator A5048702442 @default.
- W3045761520 creator A5082366563 @default.
- W3045761520 creator A5082427336 @default.
- W3045761520 date "2020-07-28" @default.
- W3045761520 modified "2023-10-11" @default.
- W3045761520 title "Growth Curves for Children with X-linked Hypophosphatemia" @default.
- W3045761520 cites W1985742682 @default.
- W3045761520 cites W2011289811 @default.
- W3045761520 cites W2054433727 @default.
- W3045761520 cites W2099098460 @default.
- W3045761520 cites W2111175632 @default.
- W3045761520 cites W2140330355 @default.
- W3045761520 cites W2165053324 @default.
- W3045761520 cites W2170926564 @default.
- W3045761520 cites W2339275496 @default.
- W3045761520 cites W2803769911 @default.
- W3045761520 cites W2909832575 @default.
- W3045761520 cites W2946559089 @default.
- W3045761520 doi "https://doi.org/10.1210/clinem/dgaa495" @default.
- W3045761520 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7448934" @default.
- W3045761520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32721016" @default.
- W3045761520 hasPublicationYear "2020" @default.
- W3045761520 type Work @default.
- W3045761520 sameAs 3045761520 @default.
- W3045761520 citedByCount "22" @default.
- W3045761520 countsByYear W30457615202021 @default.
- W3045761520 countsByYear W30457615202022 @default.
- W3045761520 countsByYear W30457615202023 @default.
- W3045761520 crossrefType "journal-article" @default.
- W3045761520 hasAuthorship W3045761520A5006764055 @default.
- W3045761520 hasAuthorship W3045761520A5029181443 @default.
- W3045761520 hasAuthorship W3045761520A5034334789 @default.
- W3045761520 hasAuthorship W3045761520A5036775753 @default.
- W3045761520 hasAuthorship W3045761520A5048702442 @default.
- W3045761520 hasAuthorship W3045761520A5082366563 @default.
- W3045761520 hasAuthorship W3045761520A5082427336 @default.
- W3045761520 hasBestOaLocation W30457615201 @default.
- W3045761520 hasConcept C105795698 @default.
- W3045761520 hasConcept C122048520 @default.
- W3045761520 hasConcept C187212893 @default.
- W3045761520 hasConcept C2777342250 @default.
- W3045761520 hasConcept C2908647359 @default.
- W3045761520 hasConcept C33923547 @default.
- W3045761520 hasConcept C71924100 @default.
- W3045761520 hasConcept C99454951 @default.
- W3045761520 hasConceptScore W3045761520C105795698 @default.
- W3045761520 hasConceptScore W3045761520C122048520 @default.
- W3045761520 hasConceptScore W3045761520C187212893 @default.
- W3045761520 hasConceptScore W3045761520C2777342250 @default.
- W3045761520 hasConceptScore W3045761520C2908647359 @default.
- W3045761520 hasConceptScore W3045761520C33923547 @default.
- W3045761520 hasConceptScore W3045761520C71924100 @default.
- W3045761520 hasConceptScore W3045761520C99454951 @default.
- W3045761520 hasFunder F4320314124 @default.
- W3045761520 hasFunder F4320322359 @default.
- W3045761520 hasIssue "10" @default.
- W3045761520 hasLocation W30457615201 @default.
- W3045761520 hasLocation W30457615202 @default.
- W3045761520 hasLocation W30457615203 @default.
- W3045761520 hasOpenAccess W3045761520 @default.
- W3045761520 hasPrimaryLocation W30457615201 @default.
- W3045761520 hasRelatedWork W171396937 @default.
- W3045761520 hasRelatedWork W2146048777 @default.
- W3045761520 hasRelatedWork W2165002764 @default.
- W3045761520 hasRelatedWork W2315544746 @default.
- W3045761520 hasRelatedWork W236926995 @default.
- W3045761520 hasRelatedWork W2581373113 @default.
- W3045761520 hasRelatedWork W2896339019 @default.
- W3045761520 hasRelatedWork W3045761520 @default.
- W3045761520 hasRelatedWork W3214043616 @default.
- W3045761520 hasRelatedWork W4242686752 @default.
- W3045761520 hasVolume "105" @default.
- W3045761520 isParatext "false" @default.
- W3045761520 isRetracted "false" @default.
- W3045761520 magId "3045761520" @default.
- W3045761520 workType "article" @default.