Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045831344> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W3045831344 abstract "Previous studies have reported that platelet count is associated with the progression of liver disease caused by hepatitis B virus (HBV), but there have been no reports on whether platelet count is associated with immune recovery in HIV/HBV co-infected patients.A retrospective analysis was conducted on 167 HIV-infected patients whose continuously highly active antiretroviral therapy (HAART) strategy was lamivudine +tenofovir+ efavirenz, of which 75 were HIV/HBV co-infected patients and 92 were HIV mono-infected patients. The biochemical examination results and demographic characteristics of all patients before HAART were collected, and routine blood test results (including platelet count) and immune cell count (including CD4 cells count) after all time points of HAART were obtained. All patients were observed until 72 months. CD4 cells count of 350 or 500 cells/μl 72 months after HAART served as the boundary for judging the immune reconstruction effect.The basic characteristics of HIV/HBV co-infected patients and HIV mono-infected patients were matched. All patients had a good viral response (HIV RNA <20 copies/ml, HBV DNA < 100 copies/mL) and immune response during HAART. The platelets with poor immune recovery in HIV/HBV co-infected patients were also maintained at an apparent lower level than that in patients with good immune recovery. However, this phenomenon was not found in HIV mono-infected patients. The platelet level at many time points after HAART therapy in HIV/HBV co-infected patients can predict the effect of immune recovery at 72 months after HAART.The platelet counts of HIV/HBV co-infected patients were correlated with CD4 counts during the follow-up of HAART. These results suggest that the mechanisms associated with thrombocytopenia may be involved in the regulation of immune recovery after treatment in HIV/HBV co-infected patients." @default.
- W3045831344 created "2020-08-03" @default.
- W3045831344 creator A5017568018 @default.
- W3045831344 creator A5025016842 @default.
- W3045831344 creator A5026225520 @default.
- W3045831344 creator A5045423164 @default.
- W3045831344 creator A5056545316 @default.
- W3045831344 creator A5056903875 @default.
- W3045831344 creator A5081844561 @default.
- W3045831344 date "2020-10-01" @default.
- W3045831344 modified "2023-10-04" @default.
- W3045831344 title "Assessing the association between platelets and immune recovery in HIV/HBV co-infected patients: A long-term cohort in Asia" @default.
- W3045831344 cites W2007486557 @default.
- W3045831344 cites W2017095434 @default.
- W3045831344 cites W2028610168 @default.
- W3045831344 cites W2049936515 @default.
- W3045831344 cites W2053178501 @default.
- W3045831344 cites W2070036973 @default.
- W3045831344 cites W2073332501 @default.
- W3045831344 cites W2074059462 @default.
- W3045831344 cites W2080821453 @default.
- W3045831344 cites W2141899279 @default.
- W3045831344 cites W2143403443 @default.
- W3045831344 cites W2152664737 @default.
- W3045831344 cites W2155674460 @default.
- W3045831344 cites W2183940924 @default.
- W3045831344 cites W2795808866 @default.
- W3045831344 cites W2901470592 @default.
- W3045831344 doi "https://doi.org/10.1016/j.meegid.2020.104480" @default.
- W3045831344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32736042" @default.
- W3045831344 hasPublicationYear "2020" @default.
- W3045831344 type Work @default.
- W3045831344 sameAs 3045831344 @default.
- W3045831344 citedByCount "0" @default.
- W3045831344 crossrefType "journal-article" @default.
- W3045831344 hasAuthorship W3045831344A5017568018 @default.
- W3045831344 hasAuthorship W3045831344A5025016842 @default.
- W3045831344 hasAuthorship W3045831344A5026225520 @default.
- W3045831344 hasAuthorship W3045831344A5045423164 @default.
- W3045831344 hasAuthorship W3045831344A5056545316 @default.
- W3045831344 hasAuthorship W3045831344A5056903875 @default.
- W3045831344 hasAuthorship W3045831344A5081844561 @default.
- W3045831344 hasConcept C126322002 @default.
- W3045831344 hasConcept C142462285 @default.
- W3045831344 hasConcept C159047783 @default.
- W3045831344 hasConcept C203014093 @default.
- W3045831344 hasConcept C2522874641 @default.
- W3045831344 hasConcept C2777382497 @default.
- W3045831344 hasConcept C2777813720 @default.
- W3045831344 hasConcept C2777869810 @default.
- W3045831344 hasConcept C2780593183 @default.
- W3045831344 hasConcept C2781432083 @default.
- W3045831344 hasConcept C2993143319 @default.
- W3045831344 hasConcept C3013748606 @default.
- W3045831344 hasConcept C71924100 @default.
- W3045831344 hasConcept C8891405 @default.
- W3045831344 hasConcept C89560881 @default.
- W3045831344 hasConcept C90924648 @default.
- W3045831344 hasConceptScore W3045831344C126322002 @default.
- W3045831344 hasConceptScore W3045831344C142462285 @default.
- W3045831344 hasConceptScore W3045831344C159047783 @default.
- W3045831344 hasConceptScore W3045831344C203014093 @default.
- W3045831344 hasConceptScore W3045831344C2522874641 @default.
- W3045831344 hasConceptScore W3045831344C2777382497 @default.
- W3045831344 hasConceptScore W3045831344C2777813720 @default.
- W3045831344 hasConceptScore W3045831344C2777869810 @default.
- W3045831344 hasConceptScore W3045831344C2780593183 @default.
- W3045831344 hasConceptScore W3045831344C2781432083 @default.
- W3045831344 hasConceptScore W3045831344C2993143319 @default.
- W3045831344 hasConceptScore W3045831344C3013748606 @default.
- W3045831344 hasConceptScore W3045831344C71924100 @default.
- W3045831344 hasConceptScore W3045831344C8891405 @default.
- W3045831344 hasConceptScore W3045831344C89560881 @default.
- W3045831344 hasConceptScore W3045831344C90924648 @default.
- W3045831344 hasFunder F4320321001 @default.
- W3045831344 hasLocation W30458313441 @default.
- W3045831344 hasLocation W30458313442 @default.
- W3045831344 hasOpenAccess W3045831344 @default.
- W3045831344 hasPrimaryLocation W30458313441 @default.
- W3045831344 hasRelatedWork W13313111 @default.
- W3045831344 hasRelatedWork W13787941 @default.
- W3045831344 hasRelatedWork W14186601 @default.
- W3045831344 hasRelatedWork W15498277 @default.
- W3045831344 hasRelatedWork W16765822 @default.
- W3045831344 hasRelatedWork W2076178 @default.
- W3045831344 hasRelatedWork W4437605 @default.
- W3045831344 hasRelatedWork W5027679 @default.
- W3045831344 hasRelatedWork W8616491 @default.
- W3045831344 hasRelatedWork W4638229 @default.
- W3045831344 isParatext "false" @default.
- W3045831344 isRetracted "false" @default.
- W3045831344 magId "3045831344" @default.
- W3045831344 workType "article" @default.