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- W3045859807 abstract "Analyzing the brain in terms of organizational structures at intermediate scales provides an approach to unravel the complexity arising from interactions between its large number of components. Focusing on a wiring diagram that spans the cortex, basal ganglia, and thalamus of the macaque brain, we identify robust modules in the network that provide a mesoscopic-level description of its topological architecture. Surprisingly, we find that the modular architecture facilitates rapid communication across the network, instead of localizing activity as is typically expected in networks having community organization. By considering processes of diffusive spreading and coordination, we demonstrate that the specific pattern of inter- and intramodular connectivity in the network allows propagation to be even faster than equivalent randomized networks with or without modular structure. This pattern of connectivity is seen at different scales and is conserved across principal cortical divisions, as well as subcortical structures. Furthermore, we find that the physical proximity between areas is insufficient to explain the modular organization, as similar mesoscopic structures can be obtained even after factoring out the effect of distance constraints on the connectivity. By supplementing the topological information about the macaque connectome with physical locations, volumes, and functions of the constituent areas and analyzing this augmented dataset, we reveal a counterintuitive role played by the modular architecture of the brain in promoting global coordination of its activity. It suggests a possible explanation for the ubiquity of modularity in brain networks." @default.
- W3045859807 created "2020-08-03" @default.
- W3045859807 creator A5026862922 @default.
- W3045859807 creator A5035871695 @default.
- W3045859807 creator A5081086296 @default.
- W3045859807 date "2022-11-09" @default.
- W3045859807 modified "2023-10-16" @default.
- W3045859807 title "Mesoscopic architecture enhances communication across the macaque connectome revealing structure-function correspondence in the brain" @default.
- W3045859807 cites W1510044868 @default.
- W3045859807 cites W1549290346 @default.
- W3045859807 cites W1569395231 @default.
- W3045859807 cites W1602141137 @default.
- W3045859807 cites W1644749979 @default.
- W3045859807 cites W1742512077 @default.
- W3045859807 cites W1748089690 @default.
- W3045859807 cites W1787666796 @default.
- W3045859807 cites W1796794609 @default.
- W3045859807 cites W1877812147 @default.
- W3045859807 cites W1893737596 @default.
- W3045859807 cites W1969865529 @default.
- W3045859807 cites W1977369305 @default.
- W3045859807 cites W1981678973 @default.
- W3045859807 cites W1983485726 @default.
- W3045859807 cites W1983805411 @default.
- W3045859807 cites W1984988256 @default.
- W3045859807 cites W1985983039 @default.
- W3045859807 cites W1986098213 @default.
- W3045859807 cites W1991362484 @default.
- W3045859807 cites W1994341528 @default.
- W3045859807 cites W1998071216 @default.
- W3045859807 cites W2000904439 @default.
- W3045859807 cites W2001204826 @default.
- W3045859807 cites W2003045401 @default.
- W3045859807 cites W2003397476 @default.
- W3045859807 cites W2010031803 @default.
- W3045859807 cites W2014141613 @default.
- W3045859807 cites W2017987256 @default.
- W3045859807 cites W2021947606 @default.
- W3045859807 cites W2022387796 @default.
- W3045859807 cites W2022856253 @default.
- W3045859807 cites W2024892001 @default.
- W3045859807 cites W2025543856 @default.
- W3045859807 cites W2030363891 @default.
- W3045859807 cites W2032416253 @default.
- W3045859807 cites W2040711722 @default.
- W3045859807 cites W2044465987 @default.
- W3045859807 cites W2047940964 @default.
- W3045859807 cites W2050920630 @default.
- W3045859807 cites W2051712503 @default.
- W3045859807 cites W2052007127 @default.
- W3045859807 cites W2057245137 @default.
- W3045859807 cites W2058395663 @default.
- W3045859807 cites W2061099285 @default.
- W3045859807 cites W2061891612 @default.
- W3045859807 cites W2074022443 @default.
- W3045859807 cites W2075557508 @default.
- W3045859807 cites W2076506821 @default.
- W3045859807 cites W2077711014 @default.
- W3045859807 cites W2080512970 @default.
- W3045859807 cites W2082627290 @default.
- W3045859807 cites W2088092325 @default.
- W3045859807 cites W2088199798 @default.
- W3045859807 cites W2088905667 @default.
- W3045859807 cites W2095293504 @default.
- W3045859807 cites W2099115602 @default.
- W3045859807 cites W2106430530 @default.
- W3045859807 cites W2109635955 @default.
- W3045859807 cites W2112151839 @default.
- W3045859807 cites W2113348048 @default.
- W3045859807 cites W2113625664 @default.
- W3045859807 cites W2115748265 @default.
- W3045859807 cites W2118705344 @default.
- W3045859807 cites W2121370521 @default.
- W3045859807 cites W2125050594 @default.
- W3045859807 cites W2125512581 @default.
- W3045859807 cites W2126278534 @default.
- W3045859807 cites W2128084896 @default.
- W3045859807 cites W2128366083 @default.
- W3045859807 cites W2128493489 @default.
- W3045859807 cites W2129057035 @default.
- W3045859807 cites W2131635906 @default.
- W3045859807 cites W2132957436 @default.
- W3045859807 cites W2134087859 @default.
- W3045859807 cites W2134806750 @default.
- W3045859807 cites W2135355136 @default.
- W3045859807 cites W2136639539 @default.
- W3045859807 cites W2139637968 @default.
- W3045859807 cites W2141443763 @default.
- W3045859807 cites W2143502460 @default.
- W3045859807 cites W2145687948 @default.
- W3045859807 cites W2147496327 @default.
- W3045859807 cites W2149037246 @default.
- W3045859807 cites W2150296457 @default.
- W3045859807 cites W2150449074 @default.
- W3045859807 cites W2150681956 @default.
- W3045859807 cites W2151350602 @default.
- W3045859807 cites W2151936673 @default.
- W3045859807 cites W2152090685 @default.
- W3045859807 cites W2155380400 @default.
- W3045859807 cites W2155847838 @default.