FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045869922> ?p ?o ?g. }

• W3045869922 abstract "Abstract Background Streptococcus mutans is a major cause of dental caries. Its capacity to produce biofilm is fundamental in the pathogenesis of this ubiquitous condition. As maintaining a healthy dentition is a genuine goal given the contemporary advance in caries control, researchers are striving to achieve a breakthrough in caries therapy. We are taking the anti-cariogenic properties of vitamin C a step-further, considering the well-known evidence of the inversely proportionate relationship between salivary levels of vitamin C and dental caries. The aim of this study was to determine MIC, MBC, biofilm prevention concentration (BPC), and derivative measures of vitamin C against fresh clinical isolates of S. mutans to evaluate its efficacy as an anti-cariogenic agent. Results Based on the data of four independent experiments done in quadruplicates, we found a concentration-dependent inhibitory effect of vitamin C on all S. mutans strains tested. The average MBC, MIC, and BPC of vitamin C were found to be 10.16, 9.38, and 5.61 mg/ml, respectively. Spectrophotometric quantitation of crystal violet showed diminished biofilm formation in the presence of vitamin C ( p < 0.05). When compared with gentamicin, vitamin C produced a zone of inhibition that was three times as large against the clinical isolates. Conclusion Our results show that vitamin C has a negative effect on S. mutans growth and biofilm formation. Being the first to meticulously utilize BPC to explore a well-known effect of vitamin C, this report aims to help in the instigation of trials of higher evidence that will ultimately culminate in repurposing vitamin C as a novel anti-cariogenic agent, albeit further studies are required to provide auxiliary evidence in this context." @default.
• W3045869922 created "2020-08-03" @default.
• W3045869922 creator A5001973840 @default.
• W3045869922 creator A5003462950 @default.
• W3045869922 creator A5008813650 @default.
• W3045869922 creator A5024588710 @default.
• W3045869922 creator A5037013612 @default.
• W3045869922 creator A5080810208 @default.
• W3045869922 date "2020-07-30" @default.
• W3045869922 modified "2023-09-26" @default.
• W3045869922 title "Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries" @default.
• W3045869922 cites W1966536819 @default.
• W3045869922 cites W1987144692 @default.
• W3045869922 cites W1991063382 @default.
• W3045869922 cites W2016562927 @default.
• W3045869922 cites W2027375167 @default.
• W3045869922 cites W2031184574 @default.
• W3045869922 cites W2044168644 @default.
• W3045869922 cites W2044976644 @default.
• W3045869922 cites W2067477145 @default.
• W3045869922 cites W2125603952 @default.
• W3045869922 cites W2126227682 @default.
• W3045869922 cites W2127652197 @default.
• W3045869922 cites W2136171665 @default.
• W3045869922 cites W2144440398 @default.
• W3045869922 cites W2147652807 @default.
• W3045869922 cites W2158624607 @default.
• W3045869922 cites W2168879981 @default.
• W3045869922 cites W2278488219 @default.
• W3045869922 cites W2327525037 @default.
• W3045869922 cites W2493516132 @default.
• W3045869922 cites W2553095014 @default.
• W3045869922 cites W2598265731 @default.
• W3045869922 cites W2756954786 @default.
• W3045869922 cites W2765654595 @default.
• W3045869922 cites W2771362836 @default.
• W3045869922 cites W2775856185 @default.
• W3045869922 cites W2803986511 @default.
• W3045869922 cites W2805692000 @default.
• W3045869922 cites W2886490300 @default.
• W3045869922 cites W2887890043 @default.
• W3045869922 cites W2973098004 @default.
• W3045869922 cites W4245857125 @default.
• W3045869922 cites W4251055834 @default.
• W3045869922 cites W49894026 @default.
• W3045869922 cites W2158833446 @default.
• W3045869922 doi "https://doi.org/10.1186/s12866-020-01914-4" @default.
• W3045869922 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7393720" @default.
• W3045869922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32731889" @default.
• W3045869922 hasPublicationYear "2020" @default.
• W3045869922 type Work @default.
• W3045869922 sameAs 3045869922 @default.
• W3045869922 citedByCount "12" @default.
• W3045869922 countsByYear W30458699222021 @default.
• W3045869922 countsByYear W30458699222022 @default.
• W3045869922 countsByYear W30458699222023 @default.
• W3045869922 crossrefType "journal-article" @default.
• W3045869922 hasAuthorship W3045869922A5001973840 @default.
• W3045869922 hasAuthorship W3045869922A5003462950 @default.
• W3045869922 hasAuthorship W3045869922A5008813650 @default.
• W3045869922 hasAuthorship W3045869922A5024588710 @default.
• W3045869922 hasAuthorship W3045869922A5037013612 @default.
• W3045869922 hasAuthorship W3045869922A5080810208 @default.
• W3045869922 hasBestOaLocation W30458699221 @default.
• W3045869922 hasConcept C124490489 @default.
• W3045869922 hasConcept C134018914 @default.
• W3045869922 hasConcept C185592680 @default.
• W3045869922 hasConcept C199343813 @default.
• W3045869922 hasConcept C2775832221 @default.
• W3045869922 hasConcept C2776020440 @default.
• W3045869922 hasConcept C2776940978 @default.
• W3045869922 hasConcept C2778430296 @default.
• W3045869922 hasConcept C2779914569 @default.
• W3045869922 hasConcept C2780022331 @default.
• W3045869922 hasConcept C31903555 @default.
• W3045869922 hasConcept C501593827 @default.
• W3045869922 hasConcept C523546767 @default.
• W3045869922 hasConcept C54355233 @default.
• W3045869922 hasConcept C55493867 @default.
• W3045869922 hasConcept C58123911 @default.
• W3045869922 hasConcept C71924100 @default.
• W3045869922 hasConcept C86803240 @default.
• W3045869922 hasConcept C89423630 @default.
• W3045869922 hasConceptScore W3045869922C124490489 @default.
• W3045869922 hasConceptScore W3045869922C134018914 @default.
• W3045869922 hasConceptScore W3045869922C185592680 @default.
• W3045869922 hasConceptScore W3045869922C199343813 @default.
• W3045869922 hasConceptScore W3045869922C2775832221 @default.
• W3045869922 hasConceptScore W3045869922C2776020440 @default.
• W3045869922 hasConceptScore W3045869922C2776940978 @default.
• W3045869922 hasConceptScore W3045869922C2778430296 @default.
• W3045869922 hasConceptScore W3045869922C2779914569 @default.
• W3045869922 hasConceptScore W3045869922C2780022331 @default.
• W3045869922 hasConceptScore W3045869922C31903555 @default.
• W3045869922 hasConceptScore W3045869922C501593827 @default.
• W3045869922 hasConceptScore W3045869922C523546767 @default.
• W3045869922 hasConceptScore W3045869922C54355233 @default.
• W3045869922 hasConceptScore W3045869922C55493867 @default.
• W3045869922 hasConceptScore W3045869922C58123911 @default.
• W3045869922 hasConceptScore W3045869922C71924100 @default.

• next