FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3045978511> ?p ?o ?g. }

• W3045978511 endingPage "901" @default.
• W3045978511 startingPage "889" @default.
• W3045978511 abstract "Introduction: Antibody-drug conjugates (ADC) are a new class of treatment for multiple myeloma (MM) patients, delivering a potent cytotoxic agent directly to the myeloma cell. The target is defined by the specificity of the monoclonal antibody which is linked to the cytotoxic agent. This mechanism of action minimizes bystander cell injury and allows a favorable therapeutic window.Areas covered: This review describes the rationale, pre- and clinical data for ADCs that have been and are currently in development for MM. As the treatment landscape for MM rapidly evolves, the treatment paradigm and a description of novel agents in development including immunotherapies are provided to understand how ADCs may fit in the pathway.Expert opinion: ADCs have a significant potential for the treatment for MM. As they are 'off the shelf' treatments, they can be used across nearly all MM treatment centers and to a wide range of patients. Some ADCs have specific adverse events that may require specialist input to optimally manage. The most clinically advanced ADC is belantamab mafodotin which has demonstrated clinically meaningful responses in patients with heavily pre-treated MM. Additionally, it is being combined with standard of care agents and at earlier lines of treatment." @default.
• W3045978511 created "2020-08-03" @default.
• W3045978511 creator A5025025997 @default.
• W3045978511 creator A5062080880 @default.
• W3045978511 creator A5082564837 @default.
• W3045978511 date "2020-08-12" @default.
• W3045978511 modified "2023-10-01" @default.
• W3045978511 title "Antibody-drug conjugates for multiple myeloma" @default.
• W3045978511 cites W1661103064 @default.
• W3045978511 cites W1970247466 @default.
• W3045978511 cites W1982877913 @default.
• W3045978511 cites W2001228837 @default.
• W3045978511 cites W2002048624 @default.
• W3045978511 cites W2004275290 @default.
• W3045978511 cites W2004543856 @default.
• W3045978511 cites W2007584552 @default.
• W3045978511 cites W2011742418 @default.
• W3045978511 cites W2018478612 @default.
• W3045978511 cites W2018771798 @default.
• W3045978511 cites W2020298011 @default.
• W3045978511 cites W2024520647 @default.
• W3045978511 cites W2043958889 @default.
• W3045978511 cites W2053706526 @default.
• W3045978511 cites W2061309593 @default.
• W3045978511 cites W2102694800 @default.
• W3045978511 cites W2127132803 @default.
• W3045978511 cites W2131340972 @default.
• W3045978511 cites W2137231887 @default.
• W3045978511 cites W2137881702 @default.
• W3045978511 cites W2140579395 @default.
• W3045978511 cites W2145345130 @default.
• W3045978511 cites W2155256323 @default.
• W3045978511 cites W2155366350 @default.
• W3045978511 cites W2184270030 @default.
• W3045978511 cites W2201190784 @default.
• W3045978511 cites W2202939373 @default.
• W3045978511 cites W2295721179 @default.
• W3045978511 cites W2315322079 @default.
• W3045978511 cites W2344653410 @default.
• W3045978511 cites W2422962677 @default.
• W3045978511 cites W2460376887 @default.
• W3045978511 cites W2529738115 @default.
• W3045978511 cites W2531611585 @default.
• W3045978511 cites W2550790024 @default.
• W3045978511 cites W2588087999 @default.
• W3045978511 cites W2597800737 @default.
• W3045978511 cites W2725721905 @default.
• W3045978511 cites W2737964630 @default.
• W3045978511 cites W2765861461 @default.
• W3045978511 cites W2767256995 @default.
• W3045978511 cites W2781388087 @default.
• W3045978511 cites W2791610094 @default.
• W3045978511 cites W2793831611 @default.
• W3045978511 cites W2798140657 @default.
• W3045978511 cites W2801640510 @default.
• W3045978511 cites W2890436368 @default.
• W3045978511 cites W2891360972 @default.
• W3045978511 cites W2891882983 @default.
• W3045978511 cites W2896099289 @default.
• W3045978511 cites W2899675310 @default.
• W3045978511 cites W2900068404 @default.
• W3045978511 cites W2900294328 @default.
• W3045978511 cites W2901760736 @default.
• W3045978511 cites W2902015040 @default.
• W3045978511 cites W2907078722 @default.
• W3045978511 cites W2909673413 @default.
• W3045978511 cites W2913348692 @default.
• W3045978511 cites W2915696691 @default.
• W3045978511 cites W2921533600 @default.
• W3045978511 cites W2923666301 @default.
• W3045978511 cites W2932076001 @default.
• W3045978511 cites W2943335541 @default.
• W3045978511 cites W2946032639 @default.
• W3045978511 cites W2950071015 @default.
• W3045978511 cites W2955184254 @default.
• W3045978511 cites W2966489555 @default.
• W3045978511 cites W2972402953 @default.
• W3045978511 cites W2981230549 @default.
• W3045978511 cites W2984927918 @default.
• W3045978511 cites W2987013001 @default.
• W3045978511 cites W2995934717 @default.
• W3045978511 cites W2997301227 @default.
• W3045978511 cites W3001655014 @default.
• W3045978511 cites W3006004790 @default.
• W3045978511 cites W3006655689 @default.
• W3045978511 cites W3008450454 @default.
• W3045978511 cites W3016933523 @default.
• W3045978511 cites W3031726617 @default.
• W3045978511 cites W3032142108 @default.
• W3045978511 cites W4211037848 @default.
• W3045978511 cites W4237791382 @default.
• W3045978511 doi "https://doi.org/10.1080/14712598.2020.1802422" @default.
• W3045978511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32729730" @default.
• W3045978511 hasPublicationYear "2020" @default.
• W3045978511 type Work @default.
• W3045978511 sameAs 3045978511 @default.
• W3045978511 citedByCount "13" @default.
• W3045978511 countsByYear W30459785112021 @default.

• next