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- W3045987674 abstract "The cytolethal distending toxin B subunit (CdtB) induces significant cytotoxicity and inflammation in many cell types that are involved in the pathogenesis of postinfectious irritable bowel syndrome (PI-IBS). However, the underlying mechanisms remain unclear. This study tested the potential role of Rab small GTPase 5a (Rab5a) in the process. We tested mRNA and protein expression of proinflammatory cytokines (interleukin-1β [IL-1β] and IL-6) in THP-1 macrophages by quantitative PCR (qPCR) and enzyme-linked immunosorbent assays (ELISAs), respectively." @default.
- W3045987674 created "2020-08-03" @default.
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- W3045987674 date "2020-09-18" @default.
- W3045987674 modified "2023-09-29" @default.
- W3045987674 title "Rab5a Promotes Cytolethal Distending Toxin B-Induced Cytotoxicity and Inflammation" @default.
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- W3045987674 doi "https://doi.org/10.1128/iai.00132-20" @default.
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