FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3046044235> ?p ?o ?g. }

• W3046044235 endingPage "e000593" @default.
• W3046044235 startingPage "e000593" @default.
• W3046044235 abstract "Background Detection of pneumonia-causing respiratory viruses in the nasopharynx of asymptomatic children has made their actual contribution to pneumonia unclear. We compared nasopharyngeal viral density between children with and without pneumonia to understand if viral density could be used to diagnose pneumonia. Methods Nasopharyngeal swabs (NPS) were collected from hospitalised pneumonia cases at Princess Margaret Hospital (PMH) and contemporaneous age-matched controls at PMH outpatient clinics and a local immunisation clinic in Perth, Australia. The density (copies/mL) of respiratory syncytial virus (RSV), influenza A virus (InfA), human metapneumovirus (HMPV) and rhinovirus in NPS was determined using quantitative PCR. Linear regression analysis was done to assess the trend between viral density and age in months. The association between viral density and disease status was examined using logistic regression. Area under receiver operating characteristic (AUROC) curves were assessed to determine optimal discriminatory viral density cut-offs. Results Through May 2015 to October 2017, 230 pneumonia cases and 230 controls were enrolled. Median nasopharyngeal density for any respiratory virus was not substantially higher in cases than controls (p>0.05 for each). A decreasing density trend with increasing age was observed—the trend was statistically significant for RSV (regression coefficient −0.04, p=0.004) but not for other viruses. After adjusting for demographics and other viral densities, for every log 10 copies/mL density increase, the odds of being a case increased by six times for RSV, three times for HMPV and two times for InfA. The AUROC curves were <0.70 for each virus, suggesting poor case–control discrimination based on viral density. Conclusion The nasopharyngeal density of respiratory viruses was not significantly higher in children with pneumonia than those without; however, the odds of being a case increased with increased density for some viruses. The utility of viral density, alone, in defining pneumonia was limited." @default.
• W3046044235 created "2020-08-03" @default.
• W3046044235 creator A5010698070 @default.
• W3046044235 creator A5012521967 @default.
• W3046044235 creator A5020950762 @default.
• W3046044235 creator A5030667842 @default.
• W3046044235 creator A5049164171 @default.
• W3046044235 creator A5049738363 @default.
• W3046044235 creator A5053014412 @default.
• W3046044235 creator A5055346025 @default.
• W3046044235 creator A5061616160 @default.
• W3046044235 creator A5070207222 @default.
• W3046044235 date "2020-07-01" @default.
• W3046044235 modified "2023-09-26" @default.
• W3046044235 title "Nasopharyngeal density of respiratory viruses in childhood pneumonia in a highly vaccinated setting: findings from a case–control study" @default.
• W3046044235 cites W1982235973 @default.
• W3046044235 cites W2013993424 @default.
• W3046044235 cites W2039837550 @default.
• W3046044235 cites W2055000866 @default.
• W3046044235 cites W2061979147 @default.
• W3046044235 cites W2074029700 @default.
• W3046044235 cites W2087738530 @default.
• W3046044235 cites W2088611964 @default.
• W3046044235 cites W2098196189 @default.
• W3046044235 cites W2109831018 @default.
• W3046044235 cites W2111500760 @default.
• W3046044235 cites W2115194859 @default.
• W3046044235 cites W2120839730 @default.
• W3046044235 cites W2139067986 @default.
• W3046044235 cites W2140153828 @default.
• W3046044235 cites W2142653221 @default.
• W3046044235 cites W2150296417 @default.
• W3046044235 cites W2152575748 @default.
• W3046044235 cites W2152692480 @default.
• W3046044235 cites W2290380888 @default.
• W3046044235 cites W2401178846 @default.
• W3046044235 cites W2407247183 @default.
• W3046044235 cites W2549697535 @default.
• W3046044235 cites W2559267600 @default.
• W3046044235 cites W2618230244 @default.
• W3046044235 cites W2618418809 @default.
• W3046044235 cites W2619684722 @default.
• W3046044235 cites W2727509207 @default.
• W3046044235 cites W2793680855 @default.
• W3046044235 cites W2897003742 @default.
• W3046044235 cites W2926242485 @default.
• W3046044235 cites W4239909494 @default.
• W3046044235 doi "https://doi.org/10.1136/bmjresp-2020-000593" @default.
• W3046044235 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7394014" @default.
• W3046044235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32727742" @default.
• W3046044235 hasPublicationYear "2020" @default.
• W3046044235 type Work @default.
• W3046044235 sameAs 3046044235 @default.
• W3046044235 citedByCount "1" @default.
• W3046044235 countsByYear W30460442352023 @default.
• W3046044235 crossrefType "journal-article" @default.
• W3046044235 hasAuthorship W3046044235A5010698070 @default.
• W3046044235 hasAuthorship W3046044235A5012521967 @default.
• W3046044235 hasAuthorship W3046044235A5020950762 @default.
• W3046044235 hasAuthorship W3046044235A5030667842 @default.
• W3046044235 hasAuthorship W3046044235A5049164171 @default.
• W3046044235 hasAuthorship W3046044235A5049738363 @default.
• W3046044235 hasAuthorship W3046044235A5053014412 @default.
• W3046044235 hasAuthorship W3046044235A5055346025 @default.
• W3046044235 hasAuthorship W3046044235A5061616160 @default.
• W3046044235 hasAuthorship W3046044235A5070207222 @default.
• W3046044235 hasBestOaLocation W30460442351 @default.
• W3046044235 hasConcept C126322002 @default.
• W3046044235 hasConcept C151956035 @default.
• W3046044235 hasConcept C159047783 @default.
• W3046044235 hasConcept C187212893 @default.
• W3046044235 hasConcept C203014093 @default.
• W3046044235 hasConcept C2522874641 @default.
• W3046044235 hasConcept C2776012195 @default.
• W3046044235 hasConcept C2777910003 @default.
• W3046044235 hasConcept C2777914695 @default.
• W3046044235 hasConcept C2778158872 @default.
• W3046044235 hasConcept C2778821649 @default.
• W3046044235 hasConcept C2779134260 @default.
• W3046044235 hasConcept C2779278377 @default.
• W3046044235 hasConcept C2780475896 @default.
• W3046044235 hasConcept C3008058167 @default.
• W3046044235 hasConcept C524204448 @default.
• W3046044235 hasConcept C534529494 @default.
• W3046044235 hasConcept C58471807 @default.
• W3046044235 hasConcept C71924100 @default.
• W3046044235 hasConceptScore W3046044235C126322002 @default.
• W3046044235 hasConceptScore W3046044235C151956035 @default.
• W3046044235 hasConceptScore W3046044235C159047783 @default.
• W3046044235 hasConceptScore W3046044235C187212893 @default.
• W3046044235 hasConceptScore W3046044235C203014093 @default.
• W3046044235 hasConceptScore W3046044235C2522874641 @default.
• W3046044235 hasConceptScore W3046044235C2776012195 @default.
• W3046044235 hasConceptScore W3046044235C2777910003 @default.
• W3046044235 hasConceptScore W3046044235C2777914695 @default.
• W3046044235 hasConceptScore W3046044235C2778158872 @default.
• W3046044235 hasConceptScore W3046044235C2778821649 @default.
• W3046044235 hasConceptScore W3046044235C2779134260 @default.

• next