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- W3046137259 endingPage "101891" @default.
- W3046137259 startingPage "101891" @default.
- W3046137259 abstract "Hemispheric asymmetries within the brain have been identified across taxa and have been extensively studied since the early 19th century. Here, we discuss lateralization of a brain structure, the amygdala, and how this lateralization is reshaping how we understand the role of the amygdala in pain processing. The amygdala is an almond-shaped, bilateral brain structure located within the limbic system. Historically, the amygdala was known to have a role in the processing of emotions and attaching emotional valence to memories and other experiences. The amygdala has been extensively studied in fear conditioning and affect but recently has been shown to have an important role in processing noxious information and impacting pain. The amygdala is composed of multiple nuclei; of special interest is the central nucleus of the amygdala (CeA). The CeA receives direct nociceptive inputs from the parabrachial nucleus (PBN) through the spino-parabrachio-amygdaloid pathway as well as more highly processed cortical and thalamic input via the lateral and basolateral amygdala. Although the amygdala is a bilateral brain region, most data investigating the amygdala's role in pain have been generated from the right CeA, which has an overwhelmingly pro-nociceptive function across pain models. The left CeA has often been characterized to have no effect on pain modulation, a dampened pro-nociceptive function, or most recently an anti-nociceptive function. This review explores the current literature on CeA lateralization and the hemispheres' respective roles in the processing and modulation of different forms of pain." @default.
- W3046137259 created "2020-08-03" @default.
- W3046137259 creator A5042842469 @default.
- W3046137259 creator A5043555188 @default.
- W3046137259 creator A5053007968 @default.
- W3046137259 date "2021-01-01" @default.
- W3046137259 modified "2023-10-14" @default.
- W3046137259 title "Left and right hemispheric lateralization of the amygdala in pain" @default.
- W3046137259 cites W1555297499 @default.
- W3046137259 cites W1761628643 @default.
- W3046137259 cites W1862521538 @default.
- W3046137259 cites W1883268346 @default.
- W3046137259 cites W1899857231 @default.
- W3046137259 cites W1927044428 @default.
- W3046137259 cites W1969124947 @default.
- W3046137259 cites W1971276070 @default.
- W3046137259 cites W1981044491 @default.
- W3046137259 cites W1983257841 @default.
- W3046137259 cites W1987243354 @default.
- W3046137259 cites W1987359882 @default.
- W3046137259 cites W1989982790 @default.
- W3046137259 cites W1990586248 @default.
- W3046137259 cites W1992384753 @default.
- W3046137259 cites W2000567681 @default.
- W3046137259 cites W2000681816 @default.
- W3046137259 cites W2002922392 @default.
- W3046137259 cites W2003870213 @default.
- W3046137259 cites W2004355739 @default.
- W3046137259 cites W2007012363 @default.
- W3046137259 cites W2013896083 @default.
- W3046137259 cites W2014308812 @default.
- W3046137259 cites W2017090298 @default.
- W3046137259 cites W2017221863 @default.
- W3046137259 cites W2019397294 @default.
- W3046137259 cites W2019964186 @default.
- W3046137259 cites W2024134876 @default.
- W3046137259 cites W2027072793 @default.
- W3046137259 cites W2027523863 @default.
- W3046137259 cites W2029142963 @default.
- W3046137259 cites W2034736385 @default.
- W3046137259 cites W2045927759 @default.
- W3046137259 cites W2046345358 @default.
- W3046137259 cites W2049830989 @default.
- W3046137259 cites W2054428623 @default.
- W3046137259 cites W2054476725 @default.
- W3046137259 cites W2055379848 @default.
- W3046137259 cites W2056240232 @default.
- W3046137259 cites W2060334997 @default.
- W3046137259 cites W2067253972 @default.
- W3046137259 cites W2073749580 @default.
- W3046137259 cites W2079403841 @default.
- W3046137259 cites W2080808217 @default.
- W3046137259 cites W2082797450 @default.
- W3046137259 cites W2087889245 @default.
- W3046137259 cites W2088007245 @default.
- W3046137259 cites W2092354644 @default.
- W3046137259 cites W2093532003 @default.
- W3046137259 cites W2094789510 @default.
- W3046137259 cites W2095577553 @default.
- W3046137259 cites W2095827218 @default.
- W3046137259 cites W2096134770 @default.
- W3046137259 cites W2109234832 @default.
- W3046137259 cites W2114501436 @default.
- W3046137259 cites W2117693696 @default.
- W3046137259 cites W2121366273 @default.
- W3046137259 cites W2127882576 @default.
- W3046137259 cites W2129239485 @default.
- W3046137259 cites W2133593673 @default.
- W3046137259 cites W2136408513 @default.
- W3046137259 cites W2137048847 @default.
- W3046137259 cites W2137636180 @default.
- W3046137259 cites W2138094931 @default.
- W3046137259 cites W2144933081 @default.
- W3046137259 cites W2145062794 @default.
- W3046137259 cites W2146747402 @default.
- W3046137259 cites W2151292425 @default.
- W3046137259 cites W2152156940 @default.
- W3046137259 cites W2157840151 @default.
- W3046137259 cites W2159259673 @default.
- W3046137259 cites W2159566488 @default.
- W3046137259 cites W2168778334 @default.
- W3046137259 cites W2170241325 @default.
- W3046137259 cites W2194563757 @default.
- W3046137259 cites W2232850269 @default.
- W3046137259 cites W2278798383 @default.
- W3046137259 cites W2321520174 @default.
- W3046137259 cites W2363890058 @default.
- W3046137259 cites W2411301160 @default.
- W3046137259 cites W2443156510 @default.
- W3046137259 cites W2569704946 @default.
- W3046137259 cites W2571383964 @default.
- W3046137259 cites W2608184213 @default.
- W3046137259 cites W2623656223 @default.
- W3046137259 cites W2745373007 @default.
- W3046137259 cites W2749657464 @default.
- W3046137259 cites W2801864057 @default.
- W3046137259 cites W2885751347 @default.
- W3046137259 cites W2890681211 @default.