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- W3046161702 endingPage "4182" @default.
- W3046161702 startingPage "4182" @default.
- W3046161702 abstract "Population extended life expectancy has significantly increased the risk of septic shock in an ageing population. Sepsis affects roughly 20 million people every year, resulting in over 11 million deaths. The need for faster more accurate diagnostics and better management is therefore paramount in the fight to prevent these avoidable deaths. Here we report the development of a POC device with the ability to identify a broad range of pathogens on a lateral flow platform. Namely Gram-positive and Gram-negative bacteria. The simple to use laboratory device has the potential to be automated, thus enabling an operator to carry out solid-phase lysis and room temperature RPA in situ, providing accurate results in hours rather than days. Results show there is a potential for a fully automated device in which concepts described in this paper can be integrated into a lateral flow device." @default.
- W3046161702 created "2020-08-03" @default.
- W3046161702 creator A5073107237 @default.
- W3046161702 creator A5073358366 @default.
- W3046161702 date "2020-07-28" @default.
- W3046161702 modified "2023-10-14" @default.
- W3046161702 title "Development of Solid-Phase RPA on a Lateral Flow Device for the Detection of Pathogens Related to Sepsis" @default.
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- W3046161702 doi "https://doi.org/10.3390/s20154182" @default.
- W3046161702 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7436017" @default.
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- W3046161702 hasPublicationYear "2020" @default.
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