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• W3046228164 endingPage "110778" @default.
• W3046228164 startingPage "110778" @default.
• W3046228164 abstract "In many aquatic species, the negative effect of temperature variations has a significant impact on physiological performance since beyond Tp (upper pejus) and Tc (critical temperatures), according to the oxygen- and capacity-limited thermal tolerance (OCLTT), transition to hypoxemia and mitochondrial metabolism triggers the increase in reactive oxygen species (ROS) production. However, climate change may have different spatial impact, and as a result, areas with more favorable climatic conditions (refugia) can be identified. The aim of the present study, based on cellular stress responses, is the demarcation of these areas and the preservation of commercially important marine species. Under this prism, individuals of the species Callinectes sapidus (blue crab), Sepia officinalis (common cuttlefish), Holothuria tubulosa (sea cucumber) and Venus verrucosa (clam) from Thermaikos, Pagasitikos and Vistonikos gulf were collected seasonally. The results showed an increase in the levels of several stress indicators exhibiting the triggering of Heat Shock Response, MAPK activation, apoptotic phenomena and increased ubiquitilination during the summer sampling in relation to the spring and autumn samplings concerning blue crab and clam, while no changes were observed for common cuttlefish and sea cucumber. It seems that these cellular responses consist a cytoprotective mechanism against environmental thermal stress. Regarding collection sites, for all examined species, higher cellular stress levels were observed in Pagasitikos, and lower in Vistonikos gulf. This analysis of biochemical and molecular markers is expected to provide a clearer picture for the definition of “refugia” for the above species. • Species specific responses among blue crab, sea cucumber, cuttlefish, warty venus. • Blue crab and warty venus exhibit the most significant seasonal changes. • Increased cellular stress responses in summer for the crab and venus. • 4 species: increased cellular stress responses in Pagasitikos, low in Vistonikos. • Sampling sites' temperature and geomorphology probably affect cellular responses." @default.
• W3046228164 created "2020-08-07" @default.
• W3046228164 creator A5000100196 @default.
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• W3046228164 creator A5051428774 @default.
• W3046228164 creator A5082977120 @default.
• W3046228164 date "2020-12-01" @default.
• W3046228164 modified "2023-09-27" @default.
• W3046228164 title "Seasonal cellular stress responses of commercially important invertebrates at different habitats of the North Aegean Sea" @default.
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