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• W3046228685 abstract "Purpose: To evaluate the relationship between refractive error, circadian phase, and melatonin with consideration of prior light exposure, physical activity, and sleep. Methods: Healthy young myopic (spherical equivalent refraction [SER] ≤−0.50DS) and emmetropic adults underwent noncycloplegic autorefraction and axial length (AL) measures. Objective measurements of light exposure, physical activity, and sleep were captured across 7 days by wrist-worn Actiwatch-2 devices. Questionnaires assessed sleep quality and chronotype. Hourly evening saliva sampling during a dim-light melatonin onset (DLMO) protocol evaluated circadian phase, and both morning serum and saliva samples were collected. Liquid chromatography/mass spectrometry quantified melatonin. Results: Subjects (n = 51) were aged 21.4 (interquartile range, 20.1−24.0) years. Melatonin was significantly higher in the myopic group at every evening time point and with both morning serum and saliva sampling (P ≤ 0.001 for all). DLMO-derived circadian phase did not differ between groups (P = 0.98). Multiple linear regression analysis demonstrated significant associations between serum melatonin and SER (B = –.34, β = –.42, P = 0.001), moderate activity (B = .009, β = .32, P = 0.01), and mesopic illumination (B = –.007, β = –.29, P = 0.02), F(3, 46) = 7.23, P < 0.001, R2 = 0.32, R2adjusted = .28. Myopes spent significantly more time exposed to “indoor” photopic illumination (3 to ≤1000 lux; P = 0.05), but “indoor” photopic illumination was not associated with SER, AL, or melatonin, and neither sleep, physical activity, nor any other light exposure metric differed significantly between groups (P > 0.05 for all). Conclusions: While circadian phase is aligned in adult myopes and emmetropes, myopia is associated with both elevated serum and salivary melatonin levels. Prospective studies are required to ascertain whether elevated melatonin levels occur before, during, or after myopia development." @default.
• W3046228685 created "2020-08-07" @default.
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• W3046228685 date "2020-07-30" @default.
• W3046228685 modified "2023-10-01" @default.
• W3046228685 title "Elevated Melatonin Levels Found in Young Myopic Adults Are Not Attributable to a Shift in Circadian Phase" @default.
• W3046228685 cites W1503653443 @default.
• W3046228685 cites W1626398964 @default.
• W3046228685 cites W1886115468 @default.
• W3046228685 cites W1969277188 @default.
• W3046228685 cites W1969597174 @default.
• W3046228685 cites W1974004836 @default.
• W3046228685 cites W1976311248 @default.
• W3046228685 cites W1989259302 @default.
• W3046228685 cites W1996481512 @default.
• W3046228685 cites W1999165344 @default.
• W3046228685 cites W2000835739 @default.
• W3046228685 cites W2001256485 @default.
• W3046228685 cites W2006748482 @default.
• W3046228685 cites W2007208714 @default.
• W3046228685 cites W2011689323 @default.
• W3046228685 cites W2013170465 @default.
• W3046228685 cites W2013375129 @default.
• W3046228685 cites W2021715373 @default.
• W3046228685 cites W2025478321 @default.
• W3046228685 cites W2028008479 @default.
• W3046228685 cites W2038215683 @default.
• W3046228685 cites W2039373763 @default.
• W3046228685 cites W2039931639 @default.
• W3046228685 cites W2044510143 @default.
• W3046228685 cites W2045169829 @default.
• W3046228685 cites W2057760857 @default.
• W3046228685 cites W2058311611 @default.
• W3046228685 cites W2063787806 @default.
• W3046228685 cites W2064707416 @default.
• W3046228685 cites W2067095492 @default.
• W3046228685 cites W2073148060 @default.
• W3046228685 cites W2078125977 @default.
• W3046228685 cites W2080374704 @default.
• W3046228685 cites W2084921427 @default.
• W3046228685 cites W2090214794 @default.
• W3046228685 cites W2095417713 @default.
• W3046228685 cites W2103987983 @default.
• W3046228685 cites W2109963281 @default.
• W3046228685 cites W2112509043 @default.
• W3046228685 cites W2135939475 @default.
• W3046228685 cites W2137332430 @default.
• W3046228685 cites W2138643959 @default.
• W3046228685 cites W2139143722 @default.
• W3046228685 cites W2141968080 @default.
• W3046228685 cites W2143302812 @default.
• W3046228685 cites W2150514205 @default.
• W3046228685 cites W2151487996 @default.
• W3046228685 cites W2164363851 @default.
• W3046228685 cites W2170227608 @default.
• W3046228685 cites W2263495255 @default.
• W3046228685 cites W2297359744 @default.
• W3046228685 cites W2341109211 @default.
• W3046228685 cites W2503118740 @default.
• W3046228685 cites W2521500701 @default.
• W3046228685 cites W2548207152 @default.
• W3046228685 cites W2607894244 @default.
• W3046228685 cites W2622037061 @default.
• W3046228685 cites W2734804032 @default.
• W3046228685 cites W2789455179 @default.
• W3046228685 cites W2790620694 @default.
• W3046228685 cites W2791790395 @default.
• W3046228685 cites W2802569724 @default.
• W3046228685 cites W2896581134 @default.
• W3046228685 cites W2897787090 @default.
• W3046228685 cites W2898330320 @default.
• W3046228685 cites W2900928098 @default.
• W3046228685 cites W2920748176 @default.
• W3046228685 cites W2923790393 @default.
• W3046228685 cites W2946165106 @default.
• W3046228685 cites W2950075861 @default.
• W3046228685 cites W2963991223 @default.
• W3046228685 cites W2975023821 @default.
• W3046228685 cites W2988341996 @default.
• W3046228685 cites W3013807235 @default.
• W3046228685 cites W4232506313 @default.
• W3046228685 cites W4234496617 @default.
• W3046228685 cites W4235654840 @default.
• W3046228685 cites W4246373085 @default.
• W3046228685 cites W4247063374 @default.
• W3046228685 cites W4253638855 @default.
• W3046228685 doi "https://doi.org/10.1167/iovs.61.8.45" @default.
• W3046228685 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7425780" @default.
• W3046228685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32729910" @default.
• W3046228685 hasPublicationYear "2020" @default.
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