FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3046277198> ?p ?o ?g. }

• W3046277198 endingPage "2476" @default.
• W3046277198 startingPage "2469" @default.
• W3046277198 abstract "Fairy rings resulting from a fungus–plant interaction appear worldwide. 2-Azahypoxanthine (AHX) and imidazole-4-carboxamide (ICA) were first isolated from the culture broth of one of the fairy ring-forming fungi, Lepista sordida. Afterward, a common metabolite of AHX in plants, 2-aza-8-oxohypoxanthine (AOH), was found in AHX-treated rice. The biosynthetic pathway of the three compounds that are named as fairy chemicals (FCs) in plants has been partially elucidated; however, that in mushrooms remains unknown. In this study, it was revealed that the carbon skeletons of AHX and ICA were constructed from Gly in L. sordida mycelia and the fungus metabolized 5-aminoimidazole-4-carboxamide (AICA) to both of the compounds. These results indicated that FCs were biosynthesized by a diversion of the purine metabolic pathway in L. sordida mycelia, similar to that in plants. Furthermore, we showed that recombinant adenine phosphoribosyltransferase (APRT) catalyzed reversible interconversion not only between 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranosyl 5′-monophosphate (AICAR) and AICA but also between ICA-ribotide (ICAR) and ICA. Furthermore, the presence of ICAR in L. sordida mycelia was proven for the first time by LC-MS/MS detection, and this study provided the first report that there was a novel metabolic pathway of ICA in which its ribotide was an intermediate in the fungus." @default.
• W3046277198 created "2020-08-07" @default.
• W3046277198 creator A5003382589 @default.
• W3046277198 creator A5036555344 @default.
• W3046277198 creator A5046086376 @default.
• W3046277198 creator A5049440774 @default.
• W3046277198 creator A5056453435 @default.
• W3046277198 creator A5058390989 @default.
• W3046277198 creator A5070583374 @default.
• W3046277198 creator A5073083948 @default.
• W3046277198 creator A5074134444 @default.
• W3046277198 creator A5078984314 @default.
• W3046277198 creator A5087618113 @default.
• W3046277198 creator A5089306478 @default.
• W3046277198 date "2020-07-30" @default.
• W3046277198 modified "2023-09-28" @default.
• W3046277198 title "Biosynthesis of the Fairy Chemicals, 2-Azahypoxanthine and Imidazole-4-carboxamide, in the Fairy Ring-Forming Fungus <i>Lepista sordida</i>" @default.
• W3046277198 cites W1131707487 @default.
• W3046277198 cites W1485852847 @default.
• W3046277198 cites W1498072464 @default.
• W3046277198 cites W1523075306 @default.
• W3046277198 cites W1546842811 @default.
• W3046277198 cites W1599803648 @default.
• W3046277198 cites W1844296940 @default.
• W3046277198 cites W1888432565 @default.
• W3046277198 cites W1966865000 @default.
• W3046277198 cites W1976103347 @default.
• W3046277198 cites W1977402982 @default.
• W3046277198 cites W1978232724 @default.
• W3046277198 cites W1985603814 @default.
• W3046277198 cites W1986310243 @default.
• W3046277198 cites W1995457394 @default.
• W3046277198 cites W2006902600 @default.
• W3046277198 cites W2010009005 @default.
• W3046277198 cites W2015437552 @default.
• W3046277198 cites W2017010698 @default.
• W3046277198 cites W2018740278 @default.
• W3046277198 cites W2021868913 @default.
• W3046277198 cites W203619042 @default.
• W3046277198 cites W2043409652 @default.
• W3046277198 cites W2056016010 @default.
• W3046277198 cites W2064580749 @default.
• W3046277198 cites W2070036600 @default.
• W3046277198 cites W2080640253 @default.
• W3046277198 cites W2084193273 @default.
• W3046277198 cites W2085335089 @default.
• W3046277198 cites W2094764117 @default.
• W3046277198 cites W2117801718 @default.
• W3046277198 cites W2137814749 @default.
• W3046277198 cites W2140979871 @default.
• W3046277198 cites W2166246596 @default.
• W3046277198 cites W2296261658 @default.
• W3046277198 cites W2529258950 @default.
• W3046277198 cites W2566712365 @default.
• W3046277198 cites W2791476446 @default.
• W3046277198 cites W2883818819 @default.
• W3046277198 cites W2909354975 @default.
• W3046277198 cites W2935965413 @default.
• W3046277198 cites W2956410534 @default.
• W3046277198 cites W2972515736 @default.
• W3046277198 cites W3005060408 @default.
• W3046277198 cites W4241083326 @default.
• W3046277198 doi "https://doi.org/10.1021/acs.jnatprod.0c00394" @default.
• W3046277198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32786881" @default.
• W3046277198 hasPublicationYear "2020" @default.
• W3046277198 type Work @default.
• W3046277198 sameAs 3046277198 @default.
• W3046277198 citedByCount "13" @default.
• W3046277198 countsByYear W30462771982021 @default.
• W3046277198 countsByYear W30462771982022 @default.
• W3046277198 countsByYear W30462771982023 @default.
• W3046277198 crossrefType "journal-article" @default.
• W3046277198 hasAuthorship W3046277198A5003382589 @default.
• W3046277198 hasAuthorship W3046277198A5036555344 @default.
• W3046277198 hasAuthorship W3046277198A5046086376 @default.
• W3046277198 hasAuthorship W3046277198A5049440774 @default.
• W3046277198 hasAuthorship W3046277198A5056453435 @default.
• W3046277198 hasAuthorship W3046277198A5058390989 @default.
• W3046277198 hasAuthorship W3046277198A5070583374 @default.
• W3046277198 hasAuthorship W3046277198A5073083948 @default.
• W3046277198 hasAuthorship W3046277198A5074134444 @default.
• W3046277198 hasAuthorship W3046277198A5078984314 @default.
• W3046277198 hasAuthorship W3046277198A5087618113 @default.
• W3046277198 hasAuthorship W3046277198A5089306478 @default.
• W3046277198 hasConcept C104317684 @default.
• W3046277198 hasConcept C133479454 @default.
• W3046277198 hasConcept C185592680 @default.
• W3046277198 hasConcept C2777477808 @default.
• W3046277198 hasConcept C2778327999 @default.
• W3046277198 hasConcept C2779678110 @default.
• W3046277198 hasConcept C2780874372 @default.
• W3046277198 hasConcept C512185932 @default.
• W3046277198 hasConcept C55493867 @default.
• W3046277198 hasConcept C59822182 @default.
• W3046277198 hasConcept C71240020 @default.
• W3046277198 hasConcept C86803240 @default.
• W3046277198 hasConcept C98892162 @default.
• W3046277198 hasConceptScore W3046277198C104317684 @default.

• next