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- W3046302018 endingPage "11754" @default.
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- W3046302018 abstract "Aggregation induced emission active compounds (AIEgens) have appeared as a new kind of electrochemiluminescence (ECL) emitters due to their bright emission in the aggregated state but lack functional groups. Herein, we report a quaternary ammonium salt groups-functionalized AIEgen (QAU-1) and discover that coating QAU-1 on the indium tin oxide (ITO) surface (QAU/ITO) enabled QAU-1 to display significant cathodic ECL emission compared with that of QAU-1 in the dissolved state. Inspired by this, we applied QAU-1 as emitters to develop a novel ECL biosensor (Fc-DNA/QAU/ITO) through electrostatic attraction between QAU/ITO and a ferrocene-labeled ssDNA (Fc-DNA), and the developed biosensor was employed to detect bleomycin (BLM) with high sensitivity based on the target-initiated specific cleavage and subsequent removal of Fc molecules from the electrode. We envision this work will open up a new avenue to development of high-performance ECL biosensors, which will display a significant potential application in the field of analysis." @default.
- W3046302018 created "2020-08-07" @default.
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- W3046302018 date "2020-07-30" @default.
- W3046302018 modified "2023-10-12" @default.
- W3046302018 title "Quaternary Ammonium Salt-Functionalized Tetraphenylethene Derivative Boosts Electrochemiluminescence for Highly Sensitive Aqueous-Phase Biosensing" @default.
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- W3046302018 doi "https://doi.org/10.1021/acs.analchem.0c01796" @default.
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