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• W3046314059 abstract "INTRODUCTION:Chronic Obstructive Pulmonary Disease (COPD) is a common preventable and treatable disease, is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients.AIM OF THE STUDY:1. To study the prevalence of severity of airway obstruction, sociodemographic, clinico-radiological profile in female Chronic Obstructive Pulmonary Disease. 2. To assess the correlation of COPD assessment test (CAT) and degree of airflow obstruction in Chronic Obstructive Pulmonary Disease in females. 3. To also assess the correlation between sociodemographic and clinicoradiological factors affecting the severity of airflow obstruction. MATERIALS & METHODS: 91 female patients more than 40 years of age with clinical history and symptoms suggestive of COPD with spirometric diagnosis of COPD according to GOLD guidelines 2016 with post bronchodilator FEV1/FVC under 0.70 and who satisfied the inclusion and exclusion criteria were enrolled in the study and the following were assessed Severity of symptoms,Socioeconomic status,Risk factor assessment,Nutritional status, Presence and severity of depression, Degree of airflow obstruction and reversibility, Exercise capacity,Radiological presentation.RESULTS:In our female COPD patients 71% were below the age of 60 years with 74% having high and very high CAT score and 59.2% having dyspnea of grade 3 and 4 of mMRC scale. In this study group 63.7% belonged to moderate degree of airflow limitation based on GOLD criteria, less than 10% were underweight based on BMI. Most of the patients belonged to the more symptomatic group (Group B 38% and Group D 54%) in GOLD Combined Assessment stratification of patients. In the study population 71% had exposure to solid biomass fuel with 54% having a biomass exposure index above 60. Only 3.2% were smokers. Occupational exposure to dust and chemicals present as they were construction workers (18.6%), agricultural workers (18.6%), sweepers (5.4%), cooks (5.4%) and flour handlers (5.4%). The CT Phenotypes present in our patient were Airway Predominant (45%), Mixed Phenotype (27.4%) and Emphysematous Predominant Phenotype in 16.4%. The common comorbidities were diabetes (30.8%), systemic Hypertension (35.8%), moderate depression (40.7%) and Ischemic heart disease in 9.8%. CONCLUSION: Majority of the COPD patients were below 60 years, more symptomatic with normal BMI and had moderate degree of airflow limitation. Most of them had exposure to biomass smoke even from childhood. CAT scoring had a strong correlation with severity of airflow limitation. Airway Predominant Phenotype was the commonest Phenotype. Depression was the most common comorbidity. Age, BMI, Biomass exposure, mMRC and CT Phenotype had significant association with severity of airflow limitation." @default.
• W3046314059 created "2020-08-07" @default.
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• W3046314059 date "2017-04-01" @default.
• W3046314059 modified "2023-09-23" @default.
• W3046314059 title "To study the Prevalence, Sociodemographic, Clinico-Radiological Profile and also Correlation of COPD Assessment Test (CAT) and Degree of Airflow Obstruction in Chronic Obstructive Pulmonary Disease in Females attending Tertiary Care Hospital" @default.
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