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- W3046364550 abstract "Within the last few decades, swinebreeding programs have been refined to include pork quality and novel carcasstraits alongside growth, feed efficiency, and carcass leanness in the selectionprograms for terminal sire lines with a goal to produce high quality andefficient pork product for consumers. In order to accurately select formultiple traits at once, it becomes imperative to explore their genetic andbiological architecture. The genetic architecture of traits can be exploredthrough the estimation of genetic parameters, genome-wide association studies(GWAS), gene networks and metabolic pathways. An alternative approach toexplore the genetic and biological connection between traits is based onprincipal component analysis (PCA), which generates novel “pseudo-phenotypes”and biological types (biotypes). In this context, the main objective of thisthesis was to understand the genetic and biological relationship between threegrowth, eight conventional carcass, 10 pork quality, and 18 novel carcass traitsincluded in two studies. The phenotypic data set included 2,583 records fromfemale Duroc pigs from a terminal sire line. The pedigree file contained193,764 animals and the genotype file included 21,344 animals with 35,651single nucleotide polymorphisms (SNPs). The results of the first study indicatethat genetic progress can be achieved for all 39 traits. In general, the heritabilityestimates were moderate, while most genetic correlations were generallymoderate to high and favorable. Some antagonisms were observed but thosegenetic correlations were low to moderate in nature. Thus, these relationshipscan be considered when developing selection indexes. The second study showedthat there are strong links between traits through their principal components(PCs). The main PCs identified are linked to biotypes related to growth, muscleand fat deposition, pork color, and body composition. The PCs were also used aspseudo-phenotypes in the GWAS analysis, which identified important candidategenes and metabolic pathways linked to each biotype. All of this evidence linksvaluable variables such as belly, color, marbling, and leanness traits. Ourfindings greatly contribute to the optimization of genetic and genomicselection for the inclusion of valuable and novel traits to improve productiveefficiency, novel carcass, and meat quality traits in terminal sire lines." @default.
- W3046364550 created "2020-08-07" @default.
- W3046364550 creator A5021527726 @default.
- W3046364550 date "2020-08-01" @default.
- W3046364550 modified "2023-09-22" @default.
- W3046364550 title "Genetic and biological architecture of pork quality, carcass, primal-cut and growth traits in Duroc pigs" @default.
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- W3046364550 doi "https://doi.org/10.25394/pgs.12743297.v1" @default.
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