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- W3046585788 endingPage "5529" @default.
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- W3046585788 abstract "Obesity is an excessive adipose tissue accumulation that may have detrimental effects on health. Particularly, childhood obesity has become one of the main public health problems in the 21st century, since its prevalence has widely increased in recent years. Childhood obesity is intimately related to the development of several comorbidities such as nonalcoholic fatty liver disease, dyslipidemia, type 2 diabetes mellitus, non-congenital cardiovascular disease, chronic inflammation and anemia, among others. Within this tangled interplay between these comorbidities and associated pathological conditions, obesity has been closely linked to important perturbations in iron metabolism. Iron is the second most abundant metal on Earth, but its bioavailability is hampered by its ability to form highly insoluble oxides, with iron deficiency being the most common nutritional disorder. Although every living organism requires iron, it may also cause toxic oxygen damage by generating oxygen free radicals through the Fenton reaction. Thus, iron homeostasis and metabolism must be tightly regulated in humans at every level (i.e., absorption, storage, transport, recycling). Dysregulation of any step involved in iron metabolism may lead to iron deficiencies and, eventually, to the anemic state related to obesity. In this review article, we summarize the existent evidence on the role of the most recently described components of iron metabolism and their alterations in obesity." @default.
- W3046585788 created "2020-08-07" @default.
- W3046585788 creator A5014346426 @default.
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- W3046585788 date "2020-08-01" @default.
- W3046585788 modified "2023-10-09" @default.
- W3046585788 title "Iron Metabolism in Obesity and Metabolic Syndrome" @default.
- W3046585788 cites W1491077479 @default.
- W3046585788 cites W1541725899 @default.
- W3046585788 cites W1545638544 @default.
- W3046585788 cites W1826853682 @default.
- W3046585788 cites W1893281021 @default.
- W3046585788 cites W1916951156 @default.
- W3046585788 cites W1963828400 @default.
- W3046585788 cites W1965743075 @default.
- W3046585788 cites W1966085187 @default.
- W3046585788 cites W1970672739 @default.
- W3046585788 cites W1978942485 @default.
- W3046585788 cites W1986692578 @default.
- W3046585788 cites W1987211241 @default.
- W3046585788 cites W1989986631 @default.
- W3046585788 cites W1990521190 @default.
- W3046585788 cites W1990692512 @default.
- W3046585788 cites W1992204379 @default.
- W3046585788 cites W1992739131 @default.
- W3046585788 cites W1994718205 @default.
- W3046585788 cites W1995594551 @default.
- W3046585788 cites W1996152690 @default.
- W3046585788 cites W1996821186 @default.
- W3046585788 cites W1998319035 @default.
- W3046585788 cites W1998616773 @default.
- W3046585788 cites W2002217214 @default.
- W3046585788 cites W2005970630 @default.
- W3046585788 cites W2009521826 @default.
- W3046585788 cites W2009533247 @default.
- W3046585788 cites W2012273417 @default.
- W3046585788 cites W2012741070 @default.
- W3046585788 cites W2013543828 @default.
- W3046585788 cites W2014623288 @default.
- W3046585788 cites W2022446938 @default.
- W3046585788 cites W2023289992 @default.
- W3046585788 cites W2026676289 @default.
- W3046585788 cites W2027313575 @default.
- W3046585788 cites W2028034405 @default.
- W3046585788 cites W2030982849 @default.
- W3046585788 cites W2033958201 @default.
- W3046585788 cites W2043854965 @default.
- W3046585788 cites W2045794440 @default.
- W3046585788 cites W2046392948 @default.
- W3046585788 cites W2049912996 @default.
- W3046585788 cites W2051976288 @default.
- W3046585788 cites W2052319563 @default.
- W3046585788 cites W2052766584 @default.
- W3046585788 cites W2058747854 @default.
- W3046585788 cites W2062094479 @default.
- W3046585788 cites W2062254964 @default.
- W3046585788 cites W2064671985 @default.
- W3046585788 cites W2071176238 @default.
- W3046585788 cites W2072015472 @default.
- W3046585788 cites W2072829138 @default.
- W3046585788 cites W2076768785 @default.
- W3046585788 cites W2081768689 @default.
- W3046585788 cites W2082776945 @default.
- W3046585788 cites W2084280754 @default.
- W3046585788 cites W2093550819 @default.
- W3046585788 cites W2095421717 @default.
- W3046585788 cites W2096146233 @default.
- W3046585788 cites W2110105518 @default.
- W3046585788 cites W2113822522 @default.
- W3046585788 cites W2116294859 @default.
- W3046585788 cites W2116752799 @default.
- W3046585788 cites W2119214357 @default.
- W3046585788 cites W2120681852 @default.
- W3046585788 cites W2125689907 @default.
- W3046585788 cites W2126030177 @default.
- W3046585788 cites W2128304272 @default.
- W3046585788 cites W2134182910 @default.
- W3046585788 cites W2135319698 @default.
- W3046585788 cites W2138180683 @default.
- W3046585788 cites W2141329138 @default.
- W3046585788 cites W2143980582 @default.
- W3046585788 cites W2145661719 @default.
- W3046585788 cites W2149451854 @default.
- W3046585788 cites W2152863656 @default.
- W3046585788 cites W2153500348 @default.
- W3046585788 cites W2154548181 @default.
- W3046585788 cites W2161129093 @default.
- W3046585788 cites W2168517524 @default.
- W3046585788 cites W2174098335 @default.
- W3046585788 cites W2187000747 @default.
- W3046585788 cites W2204004844 @default.
- W3046585788 cites W2207605053 @default.
- W3046585788 cites W2227751224 @default.
- W3046585788 cites W2259510040 @default.