Matches in SemOpenAlex for { <https://semopenalex.org/work/W3046857376> ?p ?o ?g. }
- W3046857376 endingPage "264" @default.
- W3046857376 startingPage "258" @default.
- W3046857376 abstract "Immunotherapy is the most promising method in the treatment of lung cancer, especially in connection with the rapidly growing development of monoclonal antibodies aimed at inhibiting immune checkpoints: anti-CTLA-4, anti-PD-1, anti-PD-L1. Classic immuno-mediated adverse events that occur with this method of treatment can affect several organs, including the lungs. Pneumonitis is a potentially life-threatening complication and often requires rapid treatment with high doses of corticosteroids and antibacterial drugs. We present the case of a 67-year-old patient with primary multiple malignant tumors of the larynx and left lung after combined treatment and incomplete treatment with Nivolumab, complicated by immuno-mediated pneumonitis. This report highlights the importance of treating patients with contraindications to chemotherapy when specific antitumor treatment is required, as well as timely detection of a rare but dangerous adverse event: immuno-mediated pneumonitis that occurs during treatment with immune checkpoint inhibitors. Thus, knowing the frequency of adverse events when using PD-1 and PD-L1 inhibitors, as well as the possible presence of comorbidities in patients, will make it easier for doctors to make informed decisions in the treatment of patients, and understanding the interaction of the tumor and the immune system will help determine the best predictors of response and further improve the results of treatment of patients with NSCLC." @default.
- W3046857376 created "2020-08-07" @default.
- W3046857376 creator A5005344633 @default.
- W3046857376 creator A5006738163 @default.
- W3046857376 creator A5010215039 @default.
- W3046857376 creator A5039194712 @default.
- W3046857376 creator A5060323973 @default.
- W3046857376 creator A5063803550 @default.
- W3046857376 creator A5077301130 @default.
- W3046857376 date "2020-07-30" @default.
- W3046857376 modified "2023-09-26" @default.
- W3046857376 title "A case report of immune-related pneumonitis after combined treatment of non small cell lung cancer" @default.
- W3046857376 cites W1586084196 @default.
- W3046857376 cites W1605630196 @default.
- W3046857376 cites W1973243798 @default.
- W3046857376 cites W2038499623 @default.
- W3046857376 cites W2101619794 @default.
- W3046857376 cites W2104347254 @default.
- W3046857376 cites W2116607009 @default.
- W3046857376 cites W2122553809 @default.
- W3046857376 cites W2156353875 @default.
- W3046857376 cites W2160834915 @default.
- W3046857376 cites W2169164143 @default.
- W3046857376 cites W2296148183 @default.
- W3046857376 cites W2508205285 @default.
- W3046857376 cites W2522337762 @default.
- W3046857376 cites W2594042408 @default.
- W3046857376 cites W2745844722 @default.
- W3046857376 cites W2790743957 @default.
- W3046857376 cites W2796582438 @default.
- W3046857376 cites W2918948206 @default.
- W3046857376 cites W2919091706 @default.
- W3046857376 cites W2940759533 @default.
- W3046857376 cites W2999417355 @default.
- W3046857376 cites W3016279284 @default.
- W3046857376 cites W3029599895 @default.
- W3046857376 doi "https://doi.org/10.21518/2079-701x-2020-9-258-264" @default.
- W3046857376 hasPublicationYear "2020" @default.
- W3046857376 type Work @default.
- W3046857376 sameAs 3046857376 @default.
- W3046857376 citedByCount "2" @default.
- W3046857376 countsByYear W30468573762021 @default.
- W3046857376 countsByYear W30468573762023 @default.
- W3046857376 crossrefType "journal-article" @default.
- W3046857376 hasAuthorship W3046857376A5005344633 @default.
- W3046857376 hasAuthorship W3046857376A5006738163 @default.
- W3046857376 hasAuthorship W3046857376A5010215039 @default.
- W3046857376 hasAuthorship W3046857376A5039194712 @default.
- W3046857376 hasAuthorship W3046857376A5060323973 @default.
- W3046857376 hasAuthorship W3046857376A5063803550 @default.
- W3046857376 hasAuthorship W3046857376A5077301130 @default.
- W3046857376 hasBestOaLocation W30468573761 @default.
- W3046857376 hasConcept C121608353 @default.
- W3046857376 hasConcept C126322002 @default.
- W3046857376 hasConcept C143998085 @default.
- W3046857376 hasConcept C177713679 @default.
- W3046857376 hasConcept C197934379 @default.
- W3046857376 hasConcept C203014093 @default.
- W3046857376 hasConcept C2775949291 @default.
- W3046857376 hasConcept C2776256026 @default.
- W3046857376 hasConcept C2776694085 @default.
- W3046857376 hasConcept C2777701055 @default.
- W3046857376 hasConcept C2777714996 @default.
- W3046857376 hasConcept C2779524853 @default.
- W3046857376 hasConcept C2780030458 @default.
- W3046857376 hasConcept C509974204 @default.
- W3046857376 hasConcept C71924100 @default.
- W3046857376 hasConcept C8891405 @default.
- W3046857376 hasConceptScore W3046857376C121608353 @default.
- W3046857376 hasConceptScore W3046857376C126322002 @default.
- W3046857376 hasConceptScore W3046857376C143998085 @default.
- W3046857376 hasConceptScore W3046857376C177713679 @default.
- W3046857376 hasConceptScore W3046857376C197934379 @default.
- W3046857376 hasConceptScore W3046857376C203014093 @default.
- W3046857376 hasConceptScore W3046857376C2775949291 @default.
- W3046857376 hasConceptScore W3046857376C2776256026 @default.
- W3046857376 hasConceptScore W3046857376C2776694085 @default.
- W3046857376 hasConceptScore W3046857376C2777701055 @default.
- W3046857376 hasConceptScore W3046857376C2777714996 @default.
- W3046857376 hasConceptScore W3046857376C2779524853 @default.
- W3046857376 hasConceptScore W3046857376C2780030458 @default.
- W3046857376 hasConceptScore W3046857376C509974204 @default.
- W3046857376 hasConceptScore W3046857376C71924100 @default.
- W3046857376 hasConceptScore W3046857376C8891405 @default.
- W3046857376 hasIssue "9" @default.
- W3046857376 hasLocation W30468573761 @default.
- W3046857376 hasLocation W30468573762 @default.
- W3046857376 hasOpenAccess W3046857376 @default.
- W3046857376 hasPrimaryLocation W30468573761 @default.
- W3046857376 hasRelatedWork W2750661428 @default.
- W3046857376 hasRelatedWork W2948845624 @default.
- W3046857376 hasRelatedWork W2981883049 @default.
- W3046857376 hasRelatedWork W2988525911 @default.
- W3046857376 hasRelatedWork W3046857376 @default.
- W3046857376 hasRelatedWork W3137670083 @default.
- W3046857376 hasRelatedWork W3206932502 @default.
- W3046857376 hasRelatedWork W3215044659 @default.
- W3046857376 hasRelatedWork W4283812751 @default.