FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3046866115> ?p ?o ?g. }

• W3046866115 endingPage "1402" @default.
• W3046866115 startingPage "1395" @default.
• W3046866115 abstract "Abstract Anti‐transcription intermediary factor 1γ (anti‐TIF1γ) antibody (Ab) is significantly associated with internal malignancies in adult patients with dermatomyositis (DM). Although pathogenesis of cancer‐associated DM is unknown, TIF1γ overexpression in tumors has been considered to be critical for the development of DM. The objective of this study was to investigate clinical characteristics of patients with anti‐TIF1γ Ab‐positive DM and elucidate risk factors that are potentially associated with internal malignancy. In addition, we compared the expression of TIF1γ in tumor tissues of patients with anti‐TIF1γ Ab‐positive DM, anti‐TIF1γ Ab‐negative DM and without DM in order to investigate the pathogenesis of cancer‐associated DM. We analyzed 77 Japanese patients with DM, and found 19 patients to be positive for anti‐TIF1γ Ab. Patients with anti‐TIF1γ Ab‐positive DM were older and presented heliotrope rash and flagellate erythema more frequently than patients without anti‐TIF1γ Ab ( P < 0.05). Interstitial lung disease (ILD) and rapidly progressive ILD, as well as palmar violaceous erythema, were less frequent in patients with anti‐TIF1γ Ab than in patients without. Furthermore, internal malignancy and dysphagia were significantly more frequent in the anti‐TIF1γ Ab‐positive group ( P < 0.01). Male sex and dysphagia were significantly associated with internal malignancy in patients with anti‐TIF1γ Ab‐positive DM ( P < 0.01 and <0.05, respectively). Using immunohistochemistry, we examined the TIF1γ expression in tumors of 11 patients with cancer‐associated DM (anti‐TIF1γ Ab‐positive, nine; anti‐TIF1γ Ab‐negative, two) and 25 patients without DM. TIF1γ was highly expressed in all tumors, and there was no significant difference in TIF1γ expression between patients with and without DM. Furthermore, TIF1γ expressions in tumors were similar irrespective of the presence of anti‐TIF1γ Ab. These results suggest that anti‐TIF1γ antibody may not be simply induced by overexpression of TIF1γ in tumors in patients with DM, but that other mechanisms may exist." @default.
• W3046866115 created "2020-08-07" @default.
• W3046866115 creator A5009036785 @default.
• W3046866115 creator A5012550681 @default.
• W3046866115 creator A5013265515 @default.
• W3046866115 creator A5018750173 @default.
• W3046866115 creator A5023668801 @default.
• W3046866115 creator A5029280623 @default.
• W3046866115 creator A5030622546 @default.
• W3046866115 creator A5037618766 @default.
• W3046866115 creator A5040951128 @default.
• W3046866115 creator A5053418699 @default.
• W3046866115 creator A5060671990 @default.
• W3046866115 creator A5062363424 @default.
• W3046866115 creator A5074929594 @default.
• W3046866115 creator A5075869021 @default.
• W3046866115 creator A5077713567 @default.
• W3046866115 creator A5079081610 @default.
• W3046866115 creator A5081576859 @default.
• W3046866115 creator A5085034288 @default.
• W3046866115 date "2020-07-30" @default.
• W3046866115 modified "2023-10-14" @default.
• W3046866115 title "Clinical features of anti‐transcription intermediary factor 1γ (TIF1γ)‐positive dermatomyositis with internal malignancy and investigation of the involvement of TIF1γ expression in tumors in the pathogenesis of cancer‐associated dermatomyositis" @default.
• W3046866115 cites W1543571147 @default.
• W3046866115 cites W1573066137 @default.
• W3046866115 cites W1836603722 @default.
• W3046866115 cites W184510336 @default.
• W3046866115 cites W1972401899 @default.
• W3046866115 cites W1994867055 @default.
• W3046866115 cites W2013679387 @default.
• W3046866115 cites W2020615609 @default.
• W3046866115 cites W2041247171 @default.
• W3046866115 cites W2044606833 @default.
• W3046866115 cites W2048592275 @default.
• W3046866115 cites W2049883540 @default.
• W3046866115 cites W2051103305 @default.
• W3046866115 cites W2052746369 @default.
• W3046866115 cites W2075231419 @default.
• W3046866115 cites W2086052247 @default.
• W3046866115 cites W2088947549 @default.
• W3046866115 cites W2096318471 @default.
• W3046866115 cites W2110272715 @default.
• W3046866115 cites W2111356860 @default.
• W3046866115 cites W2116217224 @default.
• W3046866115 cites W2119560279 @default.
• W3046866115 cites W2131648467 @default.
• W3046866115 cites W2132260682 @default.
• W3046866115 cites W2136741329 @default.
• W3046866115 cites W2137743549 @default.
• W3046866115 cites W2140091107 @default.
• W3046866115 cites W2148217321 @default.
• W3046866115 cites W2150476147 @default.
• W3046866115 cites W2158609492 @default.
• W3046866115 cites W2165911231 @default.
• W3046866115 cites W2169176766 @default.
• W3046866115 cites W2277120484 @default.
• W3046866115 cites W2314311014 @default.
• W3046866115 cites W2344270752 @default.
• W3046866115 cites W2360905742 @default.
• W3046866115 cites W2397580418 @default.
• W3046866115 cites W2494658920 @default.
• W3046866115 cites W2510142174 @default.
• W3046866115 cites W2517935739 @default.
• W3046866115 cites W2735495539 @default.
• W3046866115 cites W2747291234 @default.
• W3046866115 cites W2769178448 @default.
• W3046866115 cites W2793307603 @default.
• W3046866115 cites W2908573555 @default.
• W3046866115 cites W2977874666 @default.
• W3046866115 cites W2982472396 @default.
• W3046866115 cites W4239180165 @default.
• W3046866115 cites W4249265574 @default.
• W3046866115 cites W92170281 @default.
• W3046866115 doi "https://doi.org/10.1111/1346-8138.15526" @default.
• W3046866115 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32734678" @default.
• W3046866115 hasPublicationYear "2020" @default.
• W3046866115 type Work @default.
• W3046866115 sameAs 3046866115 @default.
• W3046866115 citedByCount "6" @default.
• W3046866115 countsByYear W30468661152022 @default.
• W3046866115 countsByYear W30468661152023 @default.
• W3046866115 crossrefType "journal-article" @default.
• W3046866115 hasAuthorship W3046866115A5009036785 @default.
• W3046866115 hasAuthorship W3046866115A5012550681 @default.
• W3046866115 hasAuthorship W3046866115A5013265515 @default.
• W3046866115 hasAuthorship W3046866115A5018750173 @default.
• W3046866115 hasAuthorship W3046866115A5023668801 @default.
• W3046866115 hasAuthorship W3046866115A5029280623 @default.
• W3046866115 hasAuthorship W3046866115A5030622546 @default.
• W3046866115 hasAuthorship W3046866115A5037618766 @default.
• W3046866115 hasAuthorship W3046866115A5040951128 @default.
• W3046866115 hasAuthorship W3046866115A5053418699 @default.
• W3046866115 hasAuthorship W3046866115A5060671990 @default.
• W3046866115 hasAuthorship W3046866115A5062363424 @default.
• W3046866115 hasAuthorship W3046866115A5074929594 @default.
• W3046866115 hasAuthorship W3046866115A5075869021 @default.
• W3046866115 hasAuthorship W3046866115A5077713567 @default.
• W3046866115 hasAuthorship W3046866115A5079081610 @default.

• next