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- W3046935331 abstract "We describe a novel strategy to increase the unit-time-productivity of flow synthesis by using hierarchical bimodal porous silica gel (HBPSG) supported palladium column reactors. Because HBPSG has a significantly large surface area, the column reactors have low pressure drop, enabling high-volume production. We demonstrated flow synthesis of the precursor of adapalene, a pharmaceutical compound, at 5 g/h which is over 10-fold greater productivity than previous approaches." @default.
- W3046935331 created "2020-08-10" @default.
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- W3046935331 date "2022-04-01" @default.
- W3046935331 modified "2023-10-13" @default.
- W3046935331 title "Flow grams-per-hour production enabled by hierarchical bimodal porous silica gel supported palladium column reactor having low pressure drop" @default.
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- W3046935331 doi "https://doi.org/10.1016/j.cattod.2020.07.014" @default.
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