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- W3046968211 abstract "An N-heterocyclic carbene and photoredox cocatalyzed α-amino-acid decarboxylative carbonylation reaction is presented. This method displays good scope generality, providing a direct pathway to access various downstream α-amino ketones under bio- and medicinally compatible conditions. Moreover, this strategy is appealing to chemical biology because it has great potential for the chemical modification of peptides or the late-stage synthesis of keto-peptides." @default.
- W3046968211 created "2020-08-10" @default.
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- W3046968211 date "2020-08-05" @default.
- W3046968211 modified "2023-10-16" @default.
- W3046968211 title "Bio- and Medicinally Compatible α-Amino-Acid Modification via Merging Photoredox and N-Heterocyclic Carbene Catalysis" @default.
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- W3046968211 doi "https://doi.org/10.1021/acs.orglett.0c02202" @default.
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