FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W304700601> ?p ?o ?g. }

• W304700601 abstract "Regional lymph node lymphocytes from five patients with primary lung cancer were analyzed for subset composition, and exposed in vitro to the polyclonal human B cell mitogen Staphylococcus aureus Cowan I (SACI) or the murine B cell mitogen lipopolysaccharide (LPS) and then fused with mouse myeloma cells for investigation at the clonal level of their antibody (Ab) production and its statistical relation to the original subset composition. No correlation was found between the proportion of CD19+, CD23+, or CD3+ cells in the lymphocyte sample prior to its exposure to either SACI or LPS, and the Ab production efficiency, defined as the ratio of the number of Ab producing wells to the total number of proliferating wells. For lymphocytes exposed to LPS, however, a strong correlation (r = 0.931, p = 0.02) was observed between the Ab production efficiency and the ratio of CD8+ to CD3+ cells (CD8/CD3) in the original sample at least within the ranges studied (CD8/CD3 = 0.216-0.288). For those exposed to SACI, no correlation was found between the Ab production efficiency and the CD8/CD3 ratio (r = 0.881, p = 0.12) or the proportion of CD8+ cells (r = 0.808, p = 0.19) in the original sample. These results suggest that the repertoire of B cells responsive to LPS is different at least in part from the repertoire responsive to SACI and that the ratio CD8/CD3 could serve as a practical predictor for Ab production by human lymphocytes stimulated with LPS." @default.
• W304700601 created "2016-06-24" @default.
• W304700601 creator A5038534920 @default.
• W304700601 creator A5052897374 @default.
• W304700601 creator A5065924920 @default.
• W304700601 creator A5081719901 @default.
• W304700601 date "1999-01-01" @default.
• W304700601 modified "2023-09-23" @default.
• W304700601 cites W1129637936 @default.
• W304700601 cites W1487447316 @default.
• W304700601 cites W1499562567 @default.
• W304700601 cites W1504879619 @default.
• W304700601 cites W1541552368 @default.
• W304700601 cites W1604245650 @default.
• W304700601 cites W1605862162 @default.
• W304700601 cites W1627956077 @default.
• W304700601 cites W1813204405 @default.
• W304700601 cites W1966236621 @default.
• W304700601 cites W1982279555 @default.
• W304700601 cites W2006458579 @default.
• W304700601 cites W2008687927 @default.
• W304700601 cites W2009224297 @default.
• W304700601 cites W2010406281 @default.
• W304700601 cites W2016057691 @default.
• W304700601 cites W2019040767 @default.
• W304700601 cites W2029157767 @default.
• W304700601 cites W2048992492 @default.
• W304700601 cites W2063336152 @default.
• W304700601 cites W2077951663 @default.
• W304700601 cites W2104779030 @default.
• W304700601 cites W2140054143 @default.
• W304700601 cites W2164363358 @default.
• W304700601 cites W2410393212 @default.
• W304700601 cites W1550668350 @default.
• W304700601 doi "https://doi.org/10.1023/a:1008052326963" @default.
• W304700601 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3463393" @default.
• W304700601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19003346" @default.
• W304700601 hasPublicationYear "1999" @default.
• W304700601 type Work @default.
• W304700601 sameAs 304700601 @default.
• W304700601 citedByCount "1" @default.
• W304700601 countsByYear W3047006012017 @default.
• W304700601 crossrefType "journal-article" @default.
• W304700601 hasAuthorship W304700601A5038534920 @default.
• W304700601 hasAuthorship W304700601A5052897374 @default.
• W304700601 hasAuthorship W304700601A5065924920 @default.
• W304700601 hasAuthorship W304700601A5081719901 @default.
• W304700601 hasBestOaLocation W3047006012 @default.
• W304700601 hasConcept C114684123 @default.
• W304700601 hasConcept C141105273 @default.
• W304700601 hasConcept C153911025 @default.
• W304700601 hasConcept C159654299 @default.
• W304700601 hasConcept C167672396 @default.
• W304700601 hasConcept C185592680 @default.
• W304700601 hasConcept C203014093 @default.
• W304700601 hasConcept C2777761686 @default.
• W304700601 hasConcept C2778957590 @default.
• W304700601 hasConcept C2780849966 @default.
• W304700601 hasConcept C34814297 @default.
• W304700601 hasConcept C86803240 @default.
• W304700601 hasConcept C8891405 @default.
• W304700601 hasConceptScore W304700601C114684123 @default.
• W304700601 hasConceptScore W304700601C141105273 @default.
• W304700601 hasConceptScore W304700601C153911025 @default.
• W304700601 hasConceptScore W304700601C159654299 @default.
• W304700601 hasConceptScore W304700601C167672396 @default.
• W304700601 hasConceptScore W304700601C185592680 @default.
• W304700601 hasConceptScore W304700601C203014093 @default.
• W304700601 hasConceptScore W304700601C2777761686 @default.
• W304700601 hasConceptScore W304700601C2778957590 @default.
• W304700601 hasConceptScore W304700601C2780849966 @default.
• W304700601 hasConceptScore W304700601C34814297 @default.
• W304700601 hasConceptScore W304700601C86803240 @default.
• W304700601 hasConceptScore W304700601C8891405 @default.
• W304700601 hasLocation W3047006011 @default.
• W304700601 hasLocation W3047006012 @default.
• W304700601 hasLocation W3047006013 @default.
• W304700601 hasLocation W3047006014 @default.
• W304700601 hasOpenAccess W304700601 @default.
• W304700601 hasPrimaryLocation W3047006011 @default.
• W304700601 hasRelatedWork W141404968 @default.
• W304700601 hasRelatedWork W1503837128 @default.
• W304700601 hasRelatedWork W1535590610 @default.
• W304700601 hasRelatedWork W1612510683 @default.
• W304700601 hasRelatedWork W1786713988 @default.
• W304700601 hasRelatedWork W1993860877 @default.
• W304700601 hasRelatedWork W2008369546 @default.
• W304700601 hasRelatedWork W2021718755 @default.
• W304700601 hasRelatedWork W2058651326 @default.
• W304700601 hasRelatedWork W2073441881 @default.
• W304700601 hasRelatedWork W2080097296 @default.
• W304700601 hasRelatedWork W2080619320 @default.
• W304700601 hasRelatedWork W2083636559 @default.
• W304700601 hasRelatedWork W2089850856 @default.
• W304700601 hasRelatedWork W2132965438 @default.
• W304700601 hasRelatedWork W2356653246 @default.
• W304700601 hasRelatedWork W2383141932 @default.
• W304700601 hasRelatedWork W2409453039 @default.
• W304700601 hasRelatedWork W2531984772 @default.
• W304700601 hasRelatedWork W306561522 @default.

• next