FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047014782> ?p ?o ?g. }

• W3047014782 endingPage "892" @default.
• W3047014782 startingPage "892" @default.
• W3047014782 abstract "Genome wide association studies (GWAS) are a well established methodology to identify genomic variants and genes that are responsible for traits of interest in all branches of the life sciences. Despite the long time this methodology has had to mature the reliable detection of genotype–phenotype associations is still a challenge for many quantitative traits mainly because of the large number of genomic loci with weak individual effects on the trait under investigation. Thus, it can be hypothesized that many genomic variants that have a small, however real, effect remain unnoticed in many GWAS approaches. Here, we propose a two-step procedure to address this problem. In a first step, cubic splines are fitted to the test statistic values and genomic regions with spline-peaks that are higher than expected by chance are considered as quantitative trait loci (QTL). Then the SNPs in these QTLs are prioritized with respect to the strength of their association with the phenotype using a Random Forests approach. As a case study, we apply our procedure to real data sets and find trustworthy numbers of, partially novel, genomic variants and genes involved in various egg quality traits." @default.
• W3047014782 created "2020-08-10" @default.
• W3047014782 creator A5000363495 @default.
• W3047014782 creator A5000589126 @default.
• W3047014782 creator A5018615886 @default.
• W3047014782 creator A5032455109 @default.
• W3047014782 creator A5085199270 @default.
• W3047014782 date "2020-08-05" @default.
• W3047014782 modified "2023-09-26" @default.
• W3047014782 title "Combining Random Forests and a Signal Detection Method Leads to the Robust Detection of Genotype-Phenotype Associations" @default.
• W3047014782 cites W1492273171 @default.
• W3047014782 cites W1510444525 @default.
• W3047014782 cites W1816932740 @default.
• W3047014782 cites W1971298736 @default.
• W3047014782 cites W1972028609 @default.
• W3047014782 cites W1978136801 @default.
• W3047014782 cites W1980168725 @default.
• W3047014782 cites W1986112393 @default.
• W3047014782 cites W1986167683 @default.
• W3047014782 cites W1993271928 @default.
• W3047014782 cites W1996080723 @default.
• W3047014782 cites W1997320920 @default.
• W3047014782 cites W2000796519 @default.
• W3047014782 cites W2005335581 @default.
• W3047014782 cites W2021535444 @default.
• W3047014782 cites W2032457672 @default.
• W3047014782 cites W2035167607 @default.
• W3047014782 cites W2040615565 @default.
• W3047014782 cites W2050978620 @default.
• W3047014782 cites W2058808597 @default.
• W3047014782 cites W2059489824 @default.
• W3047014782 cites W2060319981 @default.
• W3047014782 cites W2066279318 @default.
• W3047014782 cites W2068135230 @default.
• W3047014782 cites W2070345960 @default.
• W3047014782 cites W2079927753 @default.
• W3047014782 cites W2087025782 @default.
• W3047014782 cites W2088486634 @default.
• W3047014782 cites W2092217613 @default.
• W3047014782 cites W2104093114 @default.
• W3047014782 cites W2108237262 @default.
• W3047014782 cites W2110974472 @default.
• W3047014782 cites W2116675749 @default.
• W3047014782 cites W2125439972 @default.
• W3047014782 cites W2126323165 @default.
• W3047014782 cites W2132629429 @default.
• W3047014782 cites W2134036574 @default.
• W3047014782 cites W2150877737 @default.
• W3047014782 cites W2156564520 @default.
• W3047014782 cites W2156665896 @default.
• W3047014782 cites W2161633633 @default.
• W3047014782 cites W2169294950 @default.
• W3047014782 cites W2255654195 @default.
• W3047014782 cites W2316863042 @default.
• W3047014782 cites W2585681007 @default.
• W3047014782 cites W2588680506 @default.
• W3047014782 cites W2725988230 @default.
• W3047014782 cites W2735364716 @default.
• W3047014782 cites W2759149602 @default.
• W3047014782 cites W2759715557 @default.
• W3047014782 cites W2779954782 @default.
• W3047014782 cites W2793555278 @default.
• W3047014782 cites W2800059896 @default.
• W3047014782 cites W2800666211 @default.
• W3047014782 cites W2801470635 @default.
• W3047014782 cites W2802115440 @default.
• W3047014782 cites W2806057423 @default.
• W3047014782 cites W2811394785 @default.
• W3047014782 cites W2828403839 @default.
• W3047014782 cites W2892364685 @default.
• W3047014782 cites W2895653695 @default.
• W3047014782 cites W2911925918 @default.
• W3047014782 cites W2913075186 @default.
• W3047014782 cites W2922108535 @default.
• W3047014782 cites W2954752112 @default.
• W3047014782 cites W2959750635 @default.
• W3047014782 cites W2969301077 @default.
• W3047014782 cites W2972956532 @default.
• W3047014782 cites W2973574094 @default.
• W3047014782 cites W2980516168 @default.
• W3047014782 cites W2981502071 @default.
• W3047014782 cites W2999513822 @default.
• W3047014782 cites W3005040265 @default.
• W3047014782 cites W3005673236 @default.
• W3047014782 cites W3010769717 @default.
• W3047014782 cites W3016610742 @default.
• W3047014782 cites W3018898071 @default.
• W3047014782 cites W4254826855 @default.
• W3047014782 doi "https://doi.org/10.3390/genes11080892" @default.
• W3047014782 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7465705" @default.
• W3047014782 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32764260" @default.
• W3047014782 hasPublicationYear "2020" @default.
• W3047014782 type Work @default.
• W3047014782 sameAs 3047014782 @default.
• W3047014782 citedByCount "10" @default.
• W3047014782 countsByYear W30470147822020 @default.
• W3047014782 countsByYear W30470147822021 @default.
• W3047014782 countsByYear W30470147822022 @default.

• next