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- W3047063889 abstract "To investigate eosinophilia as a potential on-treatment biomarker for patients receiving cancer immunotherapy.We evaluated the association between eosinophilia and treatment response and toxicity in a retrospective cohort of patients receiving cancer immunotherapy.The study involved 146 patients. Eosinophilia developed in 22%. Patients who developed eosinophilia were more likely to achieve disease control (p = 0.009), with every 0.1 × 109/l rise in eosinophil count, while receiving treatment was associated with a 28% relative increased chance achieving disease control. Although there was a trend toward improved survival, there was no significant association between eosinophilia and improved overall survival (p = 0.136). Patients with eosinophilia were more likely to develop toxicity (p = 0.042).Eosinophilia is a potentially useful biomarker warranting further prospective clinical investigation." @default.
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- W3047063889 date "2020-12-01" @default.
- W3047063889 modified "2023-10-10" @default.
- W3047063889 title "A retrospective analysis of eosinophilia as a predictive marker of response and toxicity to cancer immunotherapy" @default.
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- W3047063889 doi "https://doi.org/10.2144/fsoa-2020-0070" @default.
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