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- W3047094357 abstract "The chiral title compound, C 16 H 20 N 2 O 2 , which can be used for producing active pharmaceutical ingredients for treatment of type 2 pancreatic diabetes and other pathologies dependent on insulin resistance, was prepared from (1 R ,3 S )-camphoric acid and o -phenylenediamine. It crystallized from an ethanol solution in the chiral monoclinic P2 1 space group. The five-membered ring adopts a twisted conformation with the methyl-substituted C atoms displaced by −0.273 (5) and 0.407 (5) Å from the mean plane through the other three atoms. In the crystal, molecules are linked by O—H...N hydrogen bonds, forming chains along the a -axis direction. Hirshfeld surface analysis and two-dimensional fingerprint plots were used to analyze the intermolecular contacts present in the crystal." @default.
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- W3047094357 date "2020-08-04" @default.
- W3047094357 modified "2023-09-28" @default.
- W3047094357 title "(1R,3S)-3-(1H-Benzo[d]imidazol-2-yl)-1,2,2-trimethylcyclopentane-1-carboxylic acid as a new anti-diabetic active pharmaceutical ingredient" @default.
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- W3047094357 doi "https://doi.org/10.1107/s2056989020010439" @default.
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