Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047103653> ?p ?o ?g. }
- W3047103653 abstract "Understanding how Mycobacterium tuberculosis survives during antibiotic treatment is necessary to rationally devise more effective tuberculosis (TB) chemotherapy regimens. Using genome-wide mutant fitness profiling and the mouse model of TB, we identified genes that alter antibiotic efficacy specifically in the infection environment and associated several of these genes with natural genetic variants found in drug-resistant clinical isolates. These data suggest strategies for synergistic therapies that accelerate bacterial clearance, and they identify mechanisms of adaptation to drug exposure that could influence treatment outcome." @default.
- W3047103653 created "2020-08-10" @default.
- W3047103653 creator A5034107890 @default.
- W3047103653 creator A5048876954 @default.
- W3047103653 creator A5058875576 @default.
- W3047103653 creator A5062955181 @default.
- W3047103653 creator A5072157043 @default.
- W3047103653 creator A5080490621 @default.
- W3047103653 date "2020-08-25" @default.
- W3047103653 modified "2023-10-03" @default.
- W3047103653 title "Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis" @default.
- W3047103653 cites W1414898727 @default.
- W3047103653 cites W1863711781 @default.
- W3047103653 cites W1971337268 @default.
- W3047103653 cites W1975401101 @default.
- W3047103653 cites W1979530643 @default.
- W3047103653 cites W1983275536 @default.
- W3047103653 cites W1988164605 @default.
- W3047103653 cites W1989118552 @default.
- W3047103653 cites W1991233072 @default.
- W3047103653 cites W1991855175 @default.
- W3047103653 cites W1997320786 @default.
- W3047103653 cites W1998631074 @default.
- W3047103653 cites W2006786435 @default.
- W3047103653 cites W2015905063 @default.
- W3047103653 cites W2016517200 @default.
- W3047103653 cites W2019835759 @default.
- W3047103653 cites W2032893012 @default.
- W3047103653 cites W2037575546 @default.
- W3047103653 cites W2038363827 @default.
- W3047103653 cites W2055925735 @default.
- W3047103653 cites W2056981303 @default.
- W3047103653 cites W2060872411 @default.
- W3047103653 cites W2067576392 @default.
- W3047103653 cites W2075023168 @default.
- W3047103653 cites W2078355424 @default.
- W3047103653 cites W2082507312 @default.
- W3047103653 cites W2085662298 @default.
- W3047103653 cites W2093178459 @default.
- W3047103653 cites W2093363647 @default.
- W3047103653 cites W2093975175 @default.
- W3047103653 cites W2095222153 @default.
- W3047103653 cites W2101666067 @default.
- W3047103653 cites W2108500436 @default.
- W3047103653 cites W2109431702 @default.
- W3047103653 cites W2110065044 @default.
- W3047103653 cites W2112295785 @default.
- W3047103653 cites W2122385388 @default.
- W3047103653 cites W2125112523 @default.
- W3047103653 cites W2137356220 @default.
- W3047103653 cites W2140354550 @default.
- W3047103653 cites W2164718888 @default.
- W3047103653 cites W2165418498 @default.
- W3047103653 cites W2166758514 @default.
- W3047103653 cites W2168896139 @default.
- W3047103653 cites W2343836182 @default.
- W3047103653 cites W2345284488 @default.
- W3047103653 cites W2474933141 @default.
- W3047103653 cites W2599698180 @default.
- W3047103653 cites W2613567896 @default.
- W3047103653 cites W2614705174 @default.
- W3047103653 cites W2754780457 @default.
- W3047103653 cites W2783758534 @default.
- W3047103653 cites W2788317855 @default.
- W3047103653 cites W2803413725 @default.
- W3047103653 cites W2885437209 @default.
- W3047103653 cites W2889510886 @default.
- W3047103653 cites W2896685945 @default.
- W3047103653 cites W2902271181 @default.
- W3047103653 cites W2917266290 @default.
- W3047103653 cites W2943862789 @default.
- W3047103653 cites W2952372483 @default.
- W3047103653 cites W2952692603 @default.
- W3047103653 cites W2965833449 @default.
- W3047103653 cites W2971364670 @default.
- W3047103653 cites W2991307198 @default.
- W3047103653 cites W3010069454 @default.
- W3047103653 doi "https://doi.org/10.1128/msystems.00396-20" @default.
- W3047103653 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7406225" @default.
- W3047103653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32753506" @default.
- W3047103653 hasPublicationYear "2020" @default.
- W3047103653 type Work @default.
- W3047103653 sameAs 3047103653 @default.
- W3047103653 citedByCount "33" @default.
- W3047103653 countsByYear W30471036532018 @default.
- W3047103653 countsByYear W30471036532020 @default.
- W3047103653 countsByYear W30471036532021 @default.
- W3047103653 countsByYear W30471036532022 @default.
- W3047103653 countsByYear W30471036532023 @default.
- W3047103653 crossrefType "journal-article" @default.
- W3047103653 hasAuthorship W3047103653A5034107890 @default.
- W3047103653 hasAuthorship W3047103653A5048876954 @default.
- W3047103653 hasAuthorship W3047103653A5058875576 @default.
- W3047103653 hasAuthorship W3047103653A5062955181 @default.
- W3047103653 hasAuthorship W3047103653A5072157043 @default.
- W3047103653 hasAuthorship W3047103653A5080490621 @default.
- W3047103653 hasBestOaLocation W30471036533 @default.
- W3047103653 hasConcept C104317684 @default.
- W3047103653 hasConcept C142724271 @default.
- W3047103653 hasConcept C2777975735 @default.