Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047145206> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W3047145206 abstract "Antibiotics have been widely and efficaciously used for febrile neutropenia in pediatric patients. However, reports are scant regarding the risk factors for recurrent fever after discontinuation of antibiotics in a neutropenic state. Here, we investigated these factors using data from our previously reported randomized study regarding meropenem and piperacillin/tazobactam for pediatric patients with febrile neutropenia.We analyzed a total of 170 febrile episodes where first line antibiotic treatment was effective and discontinued before neutrophil recovery.Recurrent fever was observed in 31 episodes (18%). The median interval from antibiotics discontinuation to recurrent fever was 5 days (0-27 days). Risk factors for recurrent fever were: incomplete remission of original disease; and high white blood cell count, neutrophil count, and C reactive protein levels at start of antibiotics. Moreover, lower neutrophil count at discontinuation of antibiotics, duration of neutropenia, and onset day of febrile neutropenia from start of neutropenia were also risk factors of recurrent fever. In multivariate analysis, neutrophil count at discontinuation of antibiotics <0.011 × 109/L, neutrophil count at start of antibiotics ≥0.061 × 109/L, febrile onset following <1 day after onset of neutropenia, and incomplete remission of original disease were independent risk factors for recurrent fever.Discontinuation of antibiotics while pediatric patients were still neutropenic was almost safe. However, physicians should note the risk factors of recurrent fever." @default.
- W3047145206 created "2020-08-10" @default.
- W3047145206 creator A5023507402 @default.
- W3047145206 creator A5025984719 @default.
- W3047145206 creator A5028305352 @default.
- W3047145206 creator A5029655825 @default.
- W3047145206 creator A5048999826 @default.
- W3047145206 creator A5049202353 @default.
- W3047145206 creator A5052955876 @default.
- W3047145206 date "2020-08-01" @default.
- W3047145206 modified "2023-09-27" @default.
- W3047145206 title "Analysis of antibiotics discontinuation during bone marrow suppression in childhood, adolescent and young adult patients with febrile neutropenia" @default.
- W3047145206 cites W1496212055 @default.
- W3047145206 cites W1581759419 @default.
- W3047145206 cites W1964618214 @default.
- W3047145206 cites W1980718935 @default.
- W3047145206 cites W1982893210 @default.
- W3047145206 cites W2025417594 @default.
- W3047145206 cites W2045490896 @default.
- W3047145206 cites W2061194988 @default.
- W3047145206 cites W2073544816 @default.
- W3047145206 cites W2121960517 @default.
- W3047145206 cites W2132986533 @default.
- W3047145206 cites W2136975042 @default.
- W3047145206 cites W2166895354 @default.
- W3047145206 cites W2553686892 @default.
- W3047145206 cites W3022798003 @default.
- W3047145206 doi "https://doi.org/10.1016/j.jmii.2020.07.014" @default.
- W3047145206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32800573" @default.
- W3047145206 hasPublicationYear "2020" @default.
- W3047145206 type Work @default.
- W3047145206 sameAs 3047145206 @default.
- W3047145206 citedByCount "3" @default.
- W3047145206 countsByYear W30471452062022 @default.
- W3047145206 countsByYear W30471452062023 @default.
- W3047145206 crossrefType "journal-article" @default.
- W3047145206 hasAuthorship W3047145206A5023507402 @default.
- W3047145206 hasAuthorship W3047145206A5025984719 @default.
- W3047145206 hasAuthorship W3047145206A5028305352 @default.
- W3047145206 hasAuthorship W3047145206A5029655825 @default.
- W3047145206 hasAuthorship W3047145206A5048999826 @default.
- W3047145206 hasAuthorship W3047145206A5049202353 @default.
- W3047145206 hasAuthorship W3047145206A5052955876 @default.
- W3047145206 hasBestOaLocation W30471452061 @default.
- W3047145206 hasConcept C126322002 @default.
- W3047145206 hasConcept C187212893 @default.
- W3047145206 hasConcept C2776694085 @default.
- W3047145206 hasConcept C2777063308 @default.
- W3047145206 hasConcept C2777637488 @default.
- W3047145206 hasConcept C2777858937 @default.
- W3047145206 hasConcept C2778193466 @default.
- W3047145206 hasConcept C2778488018 @default.
- W3047145206 hasConcept C2778715236 @default.
- W3047145206 hasConcept C2778850193 @default.
- W3047145206 hasConcept C501593827 @default.
- W3047145206 hasConcept C523546767 @default.
- W3047145206 hasConcept C54355233 @default.
- W3047145206 hasConcept C71924100 @default.
- W3047145206 hasConcept C74133956 @default.
- W3047145206 hasConcept C86803240 @default.
- W3047145206 hasConcept C89423630 @default.
- W3047145206 hasConceptScore W3047145206C126322002 @default.
- W3047145206 hasConceptScore W3047145206C187212893 @default.
- W3047145206 hasConceptScore W3047145206C2776694085 @default.
- W3047145206 hasConceptScore W3047145206C2777063308 @default.
- W3047145206 hasConceptScore W3047145206C2777637488 @default.
- W3047145206 hasConceptScore W3047145206C2777858937 @default.
- W3047145206 hasConceptScore W3047145206C2778193466 @default.
- W3047145206 hasConceptScore W3047145206C2778488018 @default.
- W3047145206 hasConceptScore W3047145206C2778715236 @default.
- W3047145206 hasConceptScore W3047145206C2778850193 @default.
- W3047145206 hasConceptScore W3047145206C501593827 @default.
- W3047145206 hasConceptScore W3047145206C523546767 @default.
- W3047145206 hasConceptScore W3047145206C54355233 @default.
- W3047145206 hasConceptScore W3047145206C71924100 @default.
- W3047145206 hasConceptScore W3047145206C74133956 @default.
- W3047145206 hasConceptScore W3047145206C86803240 @default.
- W3047145206 hasConceptScore W3047145206C89423630 @default.
- W3047145206 hasLocation W30471452061 @default.
- W3047145206 hasLocation W30471452062 @default.
- W3047145206 hasLocation W30471452063 @default.
- W3047145206 hasOpenAccess W3047145206 @default.
- W3047145206 hasPrimaryLocation W30471452061 @default.
- W3047145206 hasRelatedWork W145056279 @default.
- W3047145206 hasRelatedWork W1820639900 @default.
- W3047145206 hasRelatedWork W2004482386 @default.
- W3047145206 hasRelatedWork W2073544816 @default.
- W3047145206 hasRelatedWork W2080666094 @default.
- W3047145206 hasRelatedWork W2104260971 @default.
- W3047145206 hasRelatedWork W2164302723 @default.
- W3047145206 hasRelatedWork W2404471510 @default.
- W3047145206 hasRelatedWork W2765171215 @default.
- W3047145206 hasRelatedWork W3047145206 @default.
- W3047145206 isParatext "false" @default.
- W3047145206 isRetracted "false" @default.
- W3047145206 magId "3047145206" @default.
- W3047145206 workType "article" @default.