Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047568949> ?p ?o ?g. }
- W3047568949 endingPage "23" @default.
- W3047568949 startingPage "13" @default.
- W3047568949 abstract "Regulation of proteoglycan and glycosaminoglycan synthesis is critical throughout development, and to maintain normal adult functions in wound healing and the immune system, among others. It has become increasingly clear that these processes are also under tight metabolic control and that availability of carbohydrate and amino acid metabolite precursors has a role in the control of proteoglycan and glycosaminoglycan turnover. The enzyme uridine diphosphate (UDP)-glucose dehydrogenase (UGDH) produces UDP-glucuronate, an essential precursor for new glycosaminoglycan synthesis that is tightly controlled at multiple levels. Here, we review the cellular mechanisms that regulate UGDH expression, discuss the structural features of the enzyme, and use the structures to provide a context for recent studies that link post-translational modifications and allosteric modulators of UGDH to its function in downstream pathways." @default.
- W3047568949 created "2020-08-10" @default.
- W3047568949 creator A5036643896 @default.
- W3047568949 creator A5044842177 @default.
- W3047568949 creator A5046465352 @default.
- W3047568949 date "2020-08-04" @default.
- W3047568949 modified "2023-10-03" @default.
- W3047568949 title "Integration of Sugar Metabolism and Proteoglycan Synthesis by UDP-glucose Dehydrogenase" @default.
- W3047568949 cites W1847678069 @default.
- W3047568949 cites W1968428144 @default.
- W3047568949 cites W1969073961 @default.
- W3047568949 cites W1969670626 @default.
- W3047568949 cites W1984244557 @default.
- W3047568949 cites W1992655691 @default.
- W3047568949 cites W1993610078 @default.
- W3047568949 cites W1994051122 @default.
- W3047568949 cites W2000781625 @default.
- W3047568949 cites W2001593978 @default.
- W3047568949 cites W2003199291 @default.
- W3047568949 cites W2004673962 @default.
- W3047568949 cites W2009350215 @default.
- W3047568949 cites W2009511202 @default.
- W3047568949 cites W2011776967 @default.
- W3047568949 cites W2014369330 @default.
- W3047568949 cites W2028619770 @default.
- W3047568949 cites W2028651723 @default.
- W3047568949 cites W2029344289 @default.
- W3047568949 cites W2032362320 @default.
- W3047568949 cites W2032493183 @default.
- W3047568949 cites W2038111996 @default.
- W3047568949 cites W2039130421 @default.
- W3047568949 cites W2044108366 @default.
- W3047568949 cites W2049639243 @default.
- W3047568949 cites W2053092498 @default.
- W3047568949 cites W2054403738 @default.
- W3047568949 cites W2058229406 @default.
- W3047568949 cites W2062811328 @default.
- W3047568949 cites W2076421632 @default.
- W3047568949 cites W2077585152 @default.
- W3047568949 cites W2081633288 @default.
- W3047568949 cites W2084908022 @default.
- W3047568949 cites W2085347056 @default.
- W3047568949 cites W2089547522 @default.
- W3047568949 cites W2113780941 @default.
- W3047568949 cites W2129138696 @default.
- W3047568949 cites W2144234813 @default.
- W3047568949 cites W2149366256 @default.
- W3047568949 cites W2153275355 @default.
- W3047568949 cites W2167938256 @default.
- W3047568949 cites W2278423251 @default.
- W3047568949 cites W2315248125 @default.
- W3047568949 cites W2406590514 @default.
- W3047568949 cites W2438847376 @default.
- W3047568949 cites W2792075245 @default.
- W3047568949 cites W2900324446 @default.
- W3047568949 cites W2915263262 @default.
- W3047568949 cites W2950059569 @default.
- W3047568949 cites W2954805572 @default.
- W3047568949 cites W2969826061 @default.
- W3047568949 cites W2977081179 @default.
- W3047568949 cites W3000126016 @default.
- W3047568949 cites W3004405112 @default.
- W3047568949 cites W3007668693 @default.
- W3047568949 cites W3012456775 @default.
- W3047568949 cites W3012975080 @default.
- W3047568949 cites W3015810866 @default.
- W3047568949 cites W3016192703 @default.
- W3047568949 cites W3025227069 @default.
- W3047568949 cites W3039695295 @default.
- W3047568949 doi "https://doi.org/10.1369/0022155420947500" @default.
- W3047568949 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7780191" @default.
- W3047568949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32749901" @default.
- W3047568949 hasPublicationYear "2020" @default.
- W3047568949 type Work @default.
- W3047568949 sameAs 3047568949 @default.
- W3047568949 citedByCount "19" @default.
- W3047568949 countsByYear W30475689492020 @default.
- W3047568949 countsByYear W30475689492021 @default.
- W3047568949 countsByYear W30475689492022 @default.
- W3047568949 countsByYear W30475689492023 @default.
- W3047568949 crossrefType "journal-article" @default.
- W3047568949 hasAuthorship W3047568949A5036643896 @default.
- W3047568949 hasAuthorship W3047568949A5044842177 @default.
- W3047568949 hasAuthorship W3047568949A5046465352 @default.
- W3047568949 hasBestOaLocation W30475689491 @default.
- W3047568949 hasConcept C151730666 @default.
- W3047568949 hasConcept C153074725 @default.
- W3047568949 hasConcept C155138218 @default.
- W3047568949 hasConcept C185592680 @default.
- W3047568949 hasConcept C189165786 @default.
- W3047568949 hasConcept C192989942 @default.
- W3047568949 hasConcept C2779335624 @default.
- W3047568949 hasConcept C2779343474 @default.
- W3047568949 hasConcept C2910678351 @default.
- W3047568949 hasConcept C55493867 @default.
- W3047568949 hasConcept C62231903 @default.
- W3047568949 hasConcept C86803240 @default.
- W3047568949 hasConcept C95444343 @default.