Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047729039> ?p ?o ?g. }
- W3047729039 abstract "The aim of this study was to identify prognostic long non-coding RNAs (lncRNAs) and develop a multi-lncRNA signature for suvival prediction in esophageal squamous cell carcinoma (ESCC).The clinical and gene expression data from Gene Expression Omnibus database (GSE53624, n = 119) were obtianed as training set. A total of 98 paired ESCC tumor and normal tissues were detected by RNA sequencing and used as test set. Another 84 ESCC tissues were used for real-time quantitative PCR(qRT-PCR) and as an independent validation cohort. Survival analysis, Cox regression and Kaplan-Meier analysis were performed.We screened a prognostic marker of ESCC from the GSE53624 dataset and named it as the five-lncRNA signature including AC007179.1, MORF4L2-AS1, RP11-488I20.9, RP13-30A9.2, RP4-735C1.6, which could classify patients into high- and low-risk groups with significantly different survival(median survival: 1.75 years vs. 4.01 years, log rank P < 0.05). Then test dataset and validation dataset confirmed that the five-lncRNA signature can determine the prognosis of ESCC patients. Predictive independence of the prognostic marker was proved by multivariable Cox regression analyses in the three datasets (P < 0.05). In addition, the signature was found to be better than TNM stage in terms of prognosis.The five-lncRNA signature could be a good prognostic biomarker for ESCC patients and has important clinical value." @default.
- W3047729039 created "2020-08-13" @default.
- W3047729039 creator A5002436124 @default.
- W3047729039 creator A5003547177 @default.
- W3047729039 creator A5015445783 @default.
- W3047729039 creator A5023105695 @default.
- W3047729039 creator A5036858705 @default.
- W3047729039 creator A5070177200 @default.
- W3047729039 creator A5077539659 @default.
- W3047729039 creator A5086290413 @default.
- W3047729039 date "2020-08-10" @default.
- W3047729039 modified "2023-10-16" @default.
- W3047729039 title "Prognostic value of a five-lncRNA signature in esophageal squamous cell carcinoma" @default.
- W3047729039 cites W1983487149 @default.
- W3047729039 cites W1985213644 @default.
- W3047729039 cites W2013082284 @default.
- W3047729039 cites W2019801716 @default.
- W3047729039 cites W2044455269 @default.
- W3047729039 cites W2046578329 @default.
- W3047729039 cites W2047283411 @default.
- W3047729039 cites W2049740102 @default.
- W3047729039 cites W2119043602 @default.
- W3047729039 cites W2150575159 @default.
- W3047729039 cites W2157141223 @default.
- W3047729039 cites W2167663414 @default.
- W3047729039 cites W2170552969 @default.
- W3047729039 cites W2272984102 @default.
- W3047729039 cites W2291873430 @default.
- W3047729039 cites W2518890474 @default.
- W3047729039 cites W2597872842 @default.
- W3047729039 cites W2603997054 @default.
- W3047729039 cites W2735687500 @default.
- W3047729039 cites W2759355130 @default.
- W3047729039 cites W2774490145 @default.
- W3047729039 cites W2775559649 @default.
- W3047729039 cites W2789618014 @default.
- W3047729039 cites W2807533982 @default.
- W3047729039 cites W2807640767 @default.
- W3047729039 cites W2889646458 @default.
- W3047729039 cites W2899128194 @default.
- W3047729039 cites W2899291554 @default.
- W3047729039 cites W2903634737 @default.
- W3047729039 cites W2947017644 @default.
- W3047729039 cites W2973545632 @default.
- W3047729039 cites W2982780080 @default.
- W3047729039 cites W2989676778 @default.
- W3047729039 cites W4211125721 @default.
- W3047729039 doi "https://doi.org/10.1186/s12935-020-01480-9" @default.
- W3047729039 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7419219" @default.
- W3047729039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32831646" @default.
- W3047729039 hasPublicationYear "2020" @default.
- W3047729039 type Work @default.
- W3047729039 sameAs 3047729039 @default.
- W3047729039 citedByCount "8" @default.
- W3047729039 countsByYear W30477290392021 @default.
- W3047729039 countsByYear W30477290392022 @default.
- W3047729039 countsByYear W30477290392023 @default.
- W3047729039 crossrefType "journal-article" @default.
- W3047729039 hasAuthorship W3047729039A5002436124 @default.
- W3047729039 hasAuthorship W3047729039A5003547177 @default.
- W3047729039 hasAuthorship W3047729039A5015445783 @default.
- W3047729039 hasAuthorship W3047729039A5023105695 @default.
- W3047729039 hasAuthorship W3047729039A5036858705 @default.
- W3047729039 hasAuthorship W3047729039A5070177200 @default.
- W3047729039 hasAuthorship W3047729039A5077539659 @default.
- W3047729039 hasAuthorship W3047729039A5086290413 @default.
- W3047729039 hasBestOaLocation W30477290391 @default.
- W3047729039 hasConcept C104317684 @default.
- W3047729039 hasConcept C10515644 @default.
- W3047729039 hasConcept C121608353 @default.
- W3047729039 hasConcept C126322002 @default.
- W3047729039 hasConcept C143998085 @default.
- W3047729039 hasConcept C146357865 @default.
- W3047729039 hasConcept C151730666 @default.
- W3047729039 hasConcept C2779742542 @default.
- W3047729039 hasConcept C2781197716 @default.
- W3047729039 hasConcept C2994415158 @default.
- W3047729039 hasConcept C50382708 @default.
- W3047729039 hasConcept C55493867 @default.
- W3047729039 hasConcept C62203573 @default.
- W3047729039 hasConcept C67705224 @default.
- W3047729039 hasConcept C71924100 @default.
- W3047729039 hasConcept C86803240 @default.
- W3047729039 hasConceptScore W3047729039C104317684 @default.
- W3047729039 hasConceptScore W3047729039C10515644 @default.
- W3047729039 hasConceptScore W3047729039C121608353 @default.
- W3047729039 hasConceptScore W3047729039C126322002 @default.
- W3047729039 hasConceptScore W3047729039C143998085 @default.
- W3047729039 hasConceptScore W3047729039C146357865 @default.
- W3047729039 hasConceptScore W3047729039C151730666 @default.
- W3047729039 hasConceptScore W3047729039C2779742542 @default.
- W3047729039 hasConceptScore W3047729039C2781197716 @default.
- W3047729039 hasConceptScore W3047729039C2994415158 @default.
- W3047729039 hasConceptScore W3047729039C50382708 @default.
- W3047729039 hasConceptScore W3047729039C55493867 @default.
- W3047729039 hasConceptScore W3047729039C62203573 @default.
- W3047729039 hasConceptScore W3047729039C67705224 @default.
- W3047729039 hasConceptScore W3047729039C71924100 @default.
- W3047729039 hasConceptScore W3047729039C86803240 @default.
- W3047729039 hasFunder F4320321001 @default.