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- W3047736085 abstract "Thoracic aortic dissection (TAD) is one of the most lethal aortic diseases due to its acute onset, rapid progress, and high rate of aortic rupture. The pathogenesis of TAD is not completely understood. In this mini-review, we introduce three emerging experimental mouse TAD models using β-aminopropionitrile (BAPN) alone, BAPN for a prolonged duration (four weeks) and then with added infusion of angiotensin II (AngII), or co-administration of BAPN and AngII chronically. We aim to provide insights into appropriate application of these three mouse models, thereby enhancing the understanding of the molecular mechanisms of TAD." @default.
- W3047736085 created "2020-08-13" @default.
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- W3047736085 date "2020-08-01" @default.
- W3047736085 modified "2023-10-14" @default.
- W3047736085 title "Induction of thoracic aortic dissection: a mini-review of β-aminopropionitrile-related mouse models" @default.
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- W3047736085 doi "https://doi.org/10.1631/jzus.b2000022" @default.
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