FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047761608> ?p ?o ?g. }

• W3047761608 endingPage "e3455" @default.
• W3047761608 startingPage "e3446" @default.
• W3047761608 abstract "There are large knowledge gaps on the transmission dynamics of Mycobacterium tuberculosis in settings where both tuberculosis and human immunodeficiency virus (HIV) are endemic. We aimed to assess the infectiousness of tuberculosis patients coinfected with HIV.We systematically searched for studies of contacts of both HIV-positive and HIV-negative tuberculosis index cases. Our primary outcome was Mycobacterium tuberculosis infection in contacts. Data on sputum smear and lung cavitation status of index cases were extracted from each study to assess effect modification. Secondary outcomes included prevalent tuberculosis and HIV in contacts of HIV-positive and HIV-negative index cases.Of 5255 original citations identified, 32 studies met inclusion criteria, including 25 studies investigating M. tuberculosis infection (Nparticipants = 36 893), 13 on tuberculosis (Nparticipants = 18 853), and 12 on HIV positivity (Nparticipants = 18 424). Risk of M. tuberculosis infection was lower in contacts of HIV-positive index cases (odds ratio [OR], 0.67, 95% confidence interval [CI], .58-.77) but was heterogeneous (I2 = 75.1%). Two factors modified this relationship: the lung cavitary status of the index case and immunosuppression (measured through CD4 counts or HIV or acquired immunodeficiency syndrome diagnoses) among index people living with HIV. Rates of HIV were consistently higher in contacts of coinfected index cases (OR, 4.9; 95% CI, 3.0-8.0). This was modified by whether the study was in sub-Saharan Africa (OR, 2.8; 95% CI, 1.6-4.9) or in another global region (OR, 9.8; 95% CI, 5.9-16.3).Tuberculosis patients coinfected with HIV are less infectious than HIV-uninfected cases when they have severe immunosuppression or paucibacillary disease. Contacts of coinfected index cases are almost 5 times more likely to also have HIV." @default.
• W3047761608 created "2020-08-13" @default.
• W3047761608 creator A5005928579 @default.
• W3047761608 creator A5010189741 @default.
• W3047761608 creator A5029940259 @default.
• W3047761608 creator A5030428494 @default.
• W3047761608 creator A5039601141 @default.
• W3047761608 creator A5043000167 @default.
• W3047761608 creator A5068046132 @default.
• W3047761608 creator A5071373159 @default.
• W3047761608 creator A5090734562 @default.
• W3047761608 date "2020-08-08" @default.
• W3047761608 modified "2023-09-29" @default.
• W3047761608 title "Transmission Dynamics in Tuberculosis Patients With Human Immunodeficiency Virus: A Systematic Review and Meta-analysis of 32 Observational Studies" @default.
• W3047761608 cites W1204007306 @default.
• W3047761608 cites W1580034358 @default.
• W3047761608 cites W1626333398 @default.
• W3047761608 cites W1737352760 @default.
• W3047761608 cites W1964629475 @default.
• W3047761608 cites W1965988584 @default.
• W3047761608 cites W1970466708 @default.
• W3047761608 cites W1980106078 @default.
• W3047761608 cites W1988809541 @default.
• W3047761608 cites W1990260535 @default.
• W3047761608 cites W2000988467 @default.
• W3047761608 cites W2004174010 @default.
• W3047761608 cites W2025811250 @default.
• W3047761608 cites W2026253539 @default.
• W3047761608 cites W2026924893 @default.
• W3047761608 cites W2037711142 @default.
• W3047761608 cites W2039418122 @default.
• W3047761608 cites W2057915641 @default.
• W3047761608 cites W2060263894 @default.
• W3047761608 cites W2080054424 @default.
• W3047761608 cites W2083463150 @default.
• W3047761608 cites W2083799599 @default.
• W3047761608 cites W2095686128 @default.
• W3047761608 cites W2097185879 @default.
• W3047761608 cites W2100820527 @default.
• W3047761608 cites W2101107021 @default.
• W3047761608 cites W2102877325 @default.
• W3047761608 cites W2104893532 @default.
• W3047761608 cites W2105522334 @default.
• W3047761608 cites W2106498719 @default.
• W3047761608 cites W2107328434 @default.
• W3047761608 cites W2107984651 @default.
• W3047761608 cites W2109055318 @default.
• W3047761608 cites W2112147097 @default.
• W3047761608 cites W2125435699 @default.
• W3047761608 cites W2126930838 @default.
• W3047761608 cites W2138800125 @default.
• W3047761608 cites W2146122972 @default.
• W3047761608 cites W2157668830 @default.
• W3047761608 cites W2157823046 @default.
• W3047761608 cites W2158890189 @default.
• W3047761608 cites W2541786329 @default.
• W3047761608 cites W2551123814 @default.
• W3047761608 cites W2613289070 @default.
• W3047761608 cites W2766171868 @default.
• W3047761608 cites W2767044277 @default.
• W3047761608 cites W2904867414 @default.
• W3047761608 cites W3011544320 @default.
• W3047761608 doi "https://doi.org/10.1093/cid/ciaa1146" @default.
• W3047761608 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8563187" @default.
• W3047761608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32770236" @default.
• W3047761608 hasPublicationYear "2020" @default.
• W3047761608 type Work @default.
• W3047761608 sameAs 3047761608 @default.
• W3047761608 citedByCount "9" @default.
• W3047761608 countsByYear W30477616082021 @default.
• W3047761608 countsByYear W30477616082022 @default.
• W3047761608 countsByYear W30477616082023 @default.
• W3047761608 crossrefType "journal-article" @default.
• W3047761608 hasAuthorship W3047761608A5005928579 @default.
• W3047761608 hasAuthorship W3047761608A5010189741 @default.
• W3047761608 hasAuthorship W3047761608A5029940259 @default.
• W3047761608 hasAuthorship W3047761608A5030428494 @default.
• W3047761608 hasAuthorship W3047761608A5039601141 @default.
• W3047761608 hasAuthorship W3047761608A5043000167 @default.
• W3047761608 hasAuthorship W3047761608A5068046132 @default.
• W3047761608 hasAuthorship W3047761608A5071373159 @default.
• W3047761608 hasAuthorship W3047761608A5090734562 @default.
• W3047761608 hasBestOaLocation W30477616082 @default.
• W3047761608 hasConcept C119599485 @default.
• W3047761608 hasConcept C126322002 @default.
• W3047761608 hasConcept C127413603 @default.
• W3047761608 hasConcept C142724271 @default.
• W3047761608 hasConcept C156957248 @default.
• W3047761608 hasConcept C203014093 @default.
• W3047761608 hasConcept C2776301714 @default.
• W3047761608 hasConcept C2777975735 @default.
• W3047761608 hasConcept C2781069245 @default.
• W3047761608 hasConcept C44249647 @default.
• W3047761608 hasConcept C71924100 @default.
• W3047761608 hasConcept C761482 @default.
• W3047761608 hasConceptScore W3047761608C119599485 @default.
• W3047761608 hasConceptScore W3047761608C126322002 @default.
• W3047761608 hasConceptScore W3047761608C127413603 @default.

• next