FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047786228> ?p ?o ?g. }

• W3047786228 endingPage "109322" @default.
• W3047786228 startingPage "109322" @default.
• W3047786228 abstract "Chitosan exhibiting excellent functional properties was found to be potential in a wide variety of industrial and biomedical applications. The lack of biological activities and the poor mechanical properties somewhat limit its applications. To address these limitations, chemical modification has been proved to be an efficient method. Here, we immobilized arginine-glycine-aspartic acid (RGD) on chitosan molecules and incorporated the chitosan with Poly(L-lactide-co-glycolide)-Poly(ethylene glycol) (PLGA-PEG) and β-tricalcium phosphate (β-TCP) nanoparticles to obtain a chitosan-based scaffold with enhanced mechanical and biocompatible performance. XPS and FT-IR confirmed the successful grafting of RGD peptides onto the chitosan chain. The mechanical properties, hydrophilicity and degradation behaviors of the membrane were characterized by stress-strain, water contact angle, and weight loss, respectively. Cytotoxicity, cellular adhesion, and cellular viability of the scaffolds were studied by MTT assay, cell adhesion, and cell survival experiments, respectively. The advantageous mechanical properties and the hydrophilic surface of the chitosan-based scaffold were achieved by blending with PLGA-PEG. The preliminary biocompatibility studies revealed that all the scaffolds were cell compatible, and the hydrophilic surface was more suitable for cell adhesion. The scaffolds grafted with RGD exhibited high cell adhesion rate than the pure chitosan. The results suggested that the surface hydrophilicity and biocompatibility of the chitosan-based scaffolds play an important role in enhancing cell adhesion and growth." @default.
• W3047786228 created "2020-08-13" @default.
• W3047786228 creator A5008141443 @default.
• W3047786228 creator A5008874412 @default.
• W3047786228 creator A5043321108 @default.
• W3047786228 creator A5043683691 @default.
• W3047786228 creator A5055035550 @default.
• W3047786228 creator A5057262156 @default.
• W3047786228 creator A5072675599 @default.
• W3047786228 date "2020-11-01" @default.
• W3047786228 modified "2023-10-10" @default.
• W3047786228 title "A chitosan based scaffold with enhanced mechanical and biocompatible performance for biomedical applications" @default.
• W3047786228 cites W1877170794 @default.
• W3047786228 cites W1963828134 @default.
• W3047786228 cites W1983685820 @default.
• W3047786228 cites W1988181323 @default.
• W3047786228 cites W1995722262 @default.
• W3047786228 cites W1997246078 @default.
• W3047786228 cites W1999316850 @default.
• W3047786228 cites W2005821281 @default.
• W3047786228 cites W2010337583 @default.
• W3047786228 cites W2012696480 @default.
• W3047786228 cites W2013597870 @default.
• W3047786228 cites W2016302903 @default.
• W3047786228 cites W2020450503 @default.
• W3047786228 cites W2020999936 @default.
• W3047786228 cites W2024748632 @default.
• W3047786228 cites W2026400936 @default.
• W3047786228 cites W2036577920 @default.
• W3047786228 cites W2037520688 @default.
• W3047786228 cites W2040242857 @default.
• W3047786228 cites W2044074008 @default.
• W3047786228 cites W2044774878 @default.
• W3047786228 cites W2055129519 @default.
• W3047786228 cites W2056163210 @default.
• W3047786228 cites W2057846324 @default.
• W3047786228 cites W2069298614 @default.
• W3047786228 cites W2073092812 @default.
• W3047786228 cites W2078671776 @default.
• W3047786228 cites W2080793167 @default.
• W3047786228 cites W2084075508 @default.
• W3047786228 cites W2105315124 @default.
• W3047786228 cites W2105960546 @default.
• W3047786228 cites W2129196577 @default.
• W3047786228 cites W2131082021 @default.
• W3047786228 cites W2142254746 @default.
• W3047786228 cites W2146129300 @default.
• W3047786228 cites W2170133878 @default.
• W3047786228 cites W2333258576 @default.
• W3047786228 cites W2344944109 @default.
• W3047786228 cites W2586127881 @default.
• W3047786228 cites W2737722700 @default.
• W3047786228 cites W2783339065 @default.
• W3047786228 cites W2801223976 @default.
• W3047786228 cites W2944994483 @default.
• W3047786228 cites W2961119916 @default.
• W3047786228 cites W2989992428 @default.
• W3047786228 cites W656742276 @default.
• W3047786228 doi "https://doi.org/10.1016/j.polymdegradstab.2020.109322" @default.
• W3047786228 hasPublicationYear "2020" @default.
• W3047786228 type Work @default.
• W3047786228 sameAs 3047786228 @default.
• W3047786228 citedByCount "19" @default.
• W3047786228 countsByYear W30477862282020 @default.
• W3047786228 countsByYear W30477862282021 @default.
• W3047786228 countsByYear W30477862282022 @default.
• W3047786228 countsByYear W30477862282023 @default.
• W3047786228 crossrefType "journal-article" @default.
• W3047786228 hasAuthorship W3047786228A5008141443 @default.
• W3047786228 hasAuthorship W3047786228A5008874412 @default.
• W3047786228 hasAuthorship W3047786228A5043321108 @default.
• W3047786228 hasAuthorship W3047786228A5043683691 @default.
• W3047786228 hasAuthorship W3047786228A5055035550 @default.
• W3047786228 hasAuthorship W3047786228A5057262156 @default.
• W3047786228 hasAuthorship W3047786228A5072675599 @default.
• W3047786228 hasConcept C10138342 @default.
• W3047786228 hasConcept C115537861 @default.
• W3047786228 hasConcept C127413603 @default.
• W3047786228 hasConcept C136229726 @default.
• W3047786228 hasConcept C155672457 @default.
• W3047786228 hasConcept C159985019 @default.
• W3047786228 hasConcept C162324750 @default.
• W3047786228 hasConcept C171250308 @default.
• W3047786228 hasConcept C178790620 @default.
• W3047786228 hasConcept C185592680 @default.
• W3047786228 hasConcept C191897082 @default.
• W3047786228 hasConcept C192562407 @default.
• W3047786228 hasConcept C2775937945 @default.
• W3047786228 hasConcept C2777230088 @default.
• W3047786228 hasConcept C2777516009 @default.
• W3047786228 hasConcept C2778414984 @default.
• W3047786228 hasConcept C2779732960 @default.
• W3047786228 hasConcept C2780165375 @default.
• W3047786228 hasConcept C42360764 @default.
• W3047786228 hasConcept C49892992 @default.
• W3047786228 hasConcept C521977710 @default.
• W3047786228 hasConcept C54400483 @default.
• W3047786228 hasConcept C6556556 @default.

• next