FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047809656> ?p ?o ?g. }

• W3047809656 abstract "Citrus leprosis virus C (CiLV-C, genus Cilevirus, family Kitaviridae) is an atypical virus that does not spread systemically in its plant hosts. Upon its inoculation by Brevipalpus mites, only localized lesions occur, and the infection remains limited to cells around mite feeding sites. Here, we aimed to gain insights into the putative causes of viral unfitness in plants by expanding the limited knowledge of the molecular mechanisms underlying plant/kitavirid interactions. Firstly, we quantified the CiLV-C viral RNAs during the infection in Arabidopsis thaliana plants using RT-qPCR and systematized it by defining three stages of distinguishing sub-genomic and genomic RNA accumulation: i) 0-24 hours after infestation, ii) 2-4 days after infestation (dai), and iii) 6-10 dai. Accordingly, the global plant response to CiLV-C infection was assessed by RNA-Seq at each period. Results indicated a progressive reprogramming of the plant transcriptome in parallel to the increasing viral loads. Gene ontology enrichment analysis revealed the induction of cell growth-related processes at the early stages of the infection, and the triggering of the SA-mediated pathway, ROS burst and hypersensitive response (HR) at the pre-symptomatic stage. Conversely, infected plants down-regulated JA/ET-mediated pathways and processes involved in the primary metabolism including photosynthesis. Marker genes of unfolded protein response were also induced, suggesting a contribution of the endoplasmic reticulum stress to the cell death caused by the viral infection. Finally, we transiently expressed CiLV-C proteins in Nicotiana benthamiana plants to undertake their roles in the elicited plant responses. Expression of the CiLV-C P61 protein consistently triggered ROS burst, up-regulated SA- and HR-related genes, increased SA levels, reduced JA levels, and caused cell death. Mimicry of responses typically observed during CiLV-C-plant interaction indicates P61 as a putative viral effector causing the HR-like symptoms associated with the infection. Our data strengthen the hypothesis that symptoms of CiLV-C infection might be the outcome of a hypersensitive-like response during an incompatible interaction. Consequently, the locally restricted infection of CiLV-C, commonly observed across infections by kitavirids, support the thesis that these viruses, likely arising from an ancestral arthropod-infecting virus, are unable to fully circumvent plant defenses." @default.
• W3047809656 created "2020-08-13" @default.
• W3047809656 creator A5007890773 @default.
• W3047809656 creator A5018338876 @default.
• W3047809656 creator A5043911738 @default.
• W3047809656 creator A5049725989 @default.
• W3047809656 creator A5078512560 @default.
• W3047809656 creator A5080959286 @default.
• W3047809656 date "2020-08-07" @default.
• W3047809656 modified "2023-10-04" @default.
• W3047809656 title "Plant Immune System Activation Upon Citrus Leprosis Virus C Infection Is Mimicked by the Ectopic Expression of the P61 Viral Protein" @default.
• W3047809656 cites W1533583353 @default.
• W3047809656 cites W1552467995 @default.
• W3047809656 cites W1975165380 @default.
• W3047809656 cites W1980852250 @default.
• W3047809656 cites W1981016465 @default.
• W3047809656 cites W1981763026 @default.
• W3047809656 cites W1992403504 @default.
• W3047809656 cites W1995491600 @default.
• W3047809656 cites W2004764824 @default.
• W3047809656 cites W2006319328 @default.
• W3047809656 cites W2013128880 @default.
• W3047809656 cites W2015556486 @default.
• W3047809656 cites W2016937640 @default.
• W3047809656 cites W2017426520 @default.
• W3047809656 cites W2021880506 @default.
• W3047809656 cites W2034836998 @default.
• W3047809656 cites W2037382182 @default.
• W3047809656 cites W2059223767 @default.
• W3047809656 cites W2067235476 @default.
• W3047809656 cites W2071166472 @default.
• W3047809656 cites W2071789152 @default.
• W3047809656 cites W2081849794 @default.
• W3047809656 cites W2092806862 @default.
• W3047809656 cites W2093484541 @default.
• W3047809656 cites W2099887458 @default.
• W3047809656 cites W2101597047 @default.
• W3047809656 cites W2101717500 @default.
• W3047809656 cites W2102564339 @default.
• W3047809656 cites W2108616603 @default.
• W3047809656 cites W2110020535 @default.
• W3047809656 cites W2110650347 @default.
• W3047809656 cites W2114269764 @default.
• W3047809656 cites W2129997424 @default.
• W3047809656 cites W2130442690 @default.
• W3047809656 cites W2132047503 @default.
• W3047809656 cites W2138581811 @default.
• W3047809656 cites W2140735577 @default.
• W3047809656 cites W2153565955 @default.
• W3047809656 cites W2157844019 @default.
• W3047809656 cites W2171030481 @default.
• W3047809656 cites W2171788269 @default.
• W3047809656 cites W2179438025 @default.
• W3047809656 cites W2225035262 @default.
• W3047809656 cites W2411020346 @default.
• W3047809656 cites W2460160187 @default.
• W3047809656 cites W2479540212 @default.
• W3047809656 cites W2481575424 @default.
• W3047809656 cites W2493055900 @default.
• W3047809656 cites W2527973473 @default.
• W3047809656 cites W2533355719 @default.
• W3047809656 cites W2569546520 @default.
• W3047809656 cites W2783437155 @default.
• W3047809656 cites W2802180370 @default.
• W3047809656 cites W2884119167 @default.
• W3047809656 cites W2885124964 @default.
• W3047809656 cites W2886684883 @default.
• W3047809656 cites W2887566491 @default.
• W3047809656 cites W2891009187 @default.
• W3047809656 cites W2897587566 @default.
• W3047809656 cites W2916628229 @default.
• W3047809656 cites W2940168583 @default.
• W3047809656 cites W2957529010 @default.
• W3047809656 cites W2984850951 @default.
• W3047809656 cites W2988982552 @default.
• W3047809656 cites W2991046320 @default.
• W3047809656 cites W2991165410 @default.
• W3047809656 cites W2995425608 @default.
• W3047809656 cites W2999628957 @default.
• W3047809656 cites W3005769481 @default.
• W3047809656 cites W3140788513 @default.
• W3047809656 doi "https://doi.org/10.3389/fpls.2020.01188" @default.
• W3047809656 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7427430" @default.
• W3047809656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32849736" @default.
• W3047809656 hasPublicationYear "2020" @default.
• W3047809656 type Work @default.
• W3047809656 sameAs 3047809656 @default.
• W3047809656 citedByCount "13" @default.
• W3047809656 countsByYear W30478096562020 @default.
• W3047809656 countsByYear W30478096562021 @default.
• W3047809656 countsByYear W30478096562022 @default.
• W3047809656 countsByYear W30478096562023 @default.
• W3047809656 crossrefType "journal-article" @default.
• W3047809656 hasAuthorship W3047809656A5007890773 @default.
• W3047809656 hasAuthorship W3047809656A5018338876 @default.
• W3047809656 hasAuthorship W3047809656A5043911738 @default.
• W3047809656 hasAuthorship W3047809656A5049725989 @default.
• W3047809656 hasAuthorship W3047809656A5078512560 @default.
• W3047809656 hasAuthorship W3047809656A5080959286 @default.
• W3047809656 hasBestOaLocation W30478096561 @default.

• next