Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047848799> ?p ?o ?g. }
- W3047848799 abstract "Abstract Hydrogels with the ability to change shape in response to biochemical stimuli are important for biosensing, smart medicine, drug delivery, and soft robotics. Here, a family of multicomponent DNA polymerization motor gels with different polymer backbones is created, including acrylamide‐ co ‐bis‐acrylamide (Am‐BIS), poly(ethylene glycol) diacrylate (PEGDA), and gelatin‐methacryloyl (GelMA) that swell extensively in response to specific DNA sequences. A common mechanism, a polymerization motor that induces swelling is driven by a cascade of DNA hairpin insertions into hydrogel crosslinks. These multicomponent hydrogels can be photopatterned into distinct shapes, have a broad range of mechanical properties, including tunable shear moduli between 297 and 3888 Pa and enhanced biocompatibility. Human cells adhere to the GelMA‐DNA gels and remain viable during ≈70% volumetric swelling of the gel scaffold induced by DNA sequences. The results demonstrate the generality of sequential DNA hairpin insertion as a mechanism for inducing shape change in multicomponent hydrogels, suggesting widespread applicability of polymerization motor gels in biomaterials science and engineering." @default.
- W3047848799 created "2020-08-13" @default.
- W3047848799 creator A5007284033 @default.
- W3047848799 creator A5018965393 @default.
- W3047848799 creator A5034916176 @default.
- W3047848799 creator A5039204242 @default.
- W3047848799 creator A5061999013 @default.
- W3047848799 creator A5062069511 @default.
- W3047848799 creator A5069723187 @default.
- W3047848799 creator A5080071255 @default.
- W3047848799 date "2020-08-09" @default.
- W3047848799 modified "2023-10-16" @default.
- W3047848799 title "Multicomponent DNA Polymerization Motor Gels" @default.
- W3047848799 cites W1587510658 @default.
- W3047848799 cites W1748295705 @default.
- W3047848799 cites W1966315709 @default.
- W3047848799 cites W1976842528 @default.
- W3047848799 cites W1977938388 @default.
- W3047848799 cites W1982936387 @default.
- W3047848799 cites W1988994506 @default.
- W3047848799 cites W1990411959 @default.
- W3047848799 cites W1990432030 @default.
- W3047848799 cites W1991063064 @default.
- W3047848799 cites W1997549639 @default.
- W3047848799 cites W2007531409 @default.
- W3047848799 cites W2015481698 @default.
- W3047848799 cites W2021228178 @default.
- W3047848799 cites W2023067433 @default.
- W3047848799 cites W2024306244 @default.
- W3047848799 cites W2027885271 @default.
- W3047848799 cites W2030375823 @default.
- W3047848799 cites W2034722366 @default.
- W3047848799 cites W2037198776 @default.
- W3047848799 cites W2047439171 @default.
- W3047848799 cites W2050705167 @default.
- W3047848799 cites W2051842637 @default.
- W3047848799 cites W2053429769 @default.
- W3047848799 cites W2054614417 @default.
- W3047848799 cites W2054635074 @default.
- W3047848799 cites W2062107104 @default.
- W3047848799 cites W2065315696 @default.
- W3047848799 cites W2068291255 @default.
- W3047848799 cites W2070646281 @default.
- W3047848799 cites W2072100216 @default.
- W3047848799 cites W2076790416 @default.
- W3047848799 cites W2077443558 @default.
- W3047848799 cites W2089002536 @default.
- W3047848799 cites W2098351335 @default.
- W3047848799 cites W2102517120 @default.
- W3047848799 cites W2111154757 @default.
- W3047848799 cites W2115644711 @default.
- W3047848799 cites W2127786130 @default.
- W3047848799 cites W2131470126 @default.
- W3047848799 cites W2132551021 @default.
- W3047848799 cites W2134208433 @default.
- W3047848799 cites W2141947008 @default.
- W3047848799 cites W2146238633 @default.
- W3047848799 cites W2146894143 @default.
- W3047848799 cites W2155353280 @default.
- W3047848799 cites W2156411903 @default.
- W3047848799 cites W2158961840 @default.
- W3047848799 cites W2162691613 @default.
- W3047848799 cites W2163934801 @default.
- W3047848799 cites W2166585449 @default.
- W3047848799 cites W2171956751 @default.
- W3047848799 cites W2275628519 @default.
- W3047848799 cites W2325133903 @default.
- W3047848799 cites W2330702127 @default.
- W3047848799 cites W2344920256 @default.
- W3047848799 cites W2587041470 @default.
- W3047848799 cites W2587326174 @default.
- W3047848799 cites W2754164803 @default.
- W3047848799 cites W2789391538 @default.
- W3047848799 cites W2823847891 @default.
- W3047848799 cites W2891812307 @default.
- W3047848799 cites W2904532819 @default.
- W3047848799 cites W2905344744 @default.
- W3047848799 cites W2907664770 @default.
- W3047848799 cites W2916891039 @default.
- W3047848799 cites W2945825559 @default.
- W3047848799 cites W2946541628 @default.
- W3047848799 cites W2966883708 @default.
- W3047848799 cites W2990811783 @default.
- W3047848799 cites W3008592843 @default.
- W3047848799 cites W4211246526 @default.
- W3047848799 cites W4247787060 @default.
- W3047848799 cites W4251987311 @default.
- W3047848799 doi "https://doi.org/10.1002/smll.202002946" @default.
- W3047848799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32776420" @default.
- W3047848799 hasPublicationYear "2020" @default.
- W3047848799 type Work @default.
- W3047848799 sameAs 3047848799 @default.
- W3047848799 citedByCount "10" @default.
- W3047848799 countsByYear W30478487992021 @default.
- W3047848799 countsByYear W30478487992022 @default.
- W3047848799 countsByYear W30478487992023 @default.
- W3047848799 crossrefType "journal-article" @default.
- W3047848799 hasAuthorship W3047848799A5007284033 @default.
- W3047848799 hasAuthorship W3047848799A5018965393 @default.
- W3047848799 hasAuthorship W3047848799A5034916176 @default.