Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047890287> ?p ?o ?g. }
- W3047890287 endingPage "100010" @default.
- W3047890287 startingPage "100010" @default.
- W3047890287 abstract "BackgroundMultiple sclerosis (MS) is a leading cause of disability among young adults and effects considerable social and economic burdens. Data of MS incidence in China at the national level is lacking. We conducted the first nationwide hospital-based study to estimate the incidence and hospitalization burden of MS in China.MethodsThis study is based on an administrative database of the National Hospital Quality Monitoring System, which covers all 1665 tertiary hospitals in mainland China. The “Medical Record Homepage” of all patients, including 346 variables including demographic characteristics, diagnoses, procedures, and expenses etc., were uniformly collected across each tertiary hospital via standard protocol. MS was defined by the 2010 International Panel criteria for MS and was identified by ICD-10 code (G35•0).FindingsWe identified 27,336 hospital admissions for 15,060 MS patients from 2016 to 2018; amongst these patients, 9,879 were newly diagnosed. The age- and sex-adjusted incidence per 100,000 person-years is 0•235 (95% confidence interval [CI] 0•230–0•240), with 0•055 (0•050–0•060) in children and 0•288 (0•282–0•294) in adults, respectively. The female to male ratio is 2•02; the peak disease onset is age of 40–49 years. Residents in high-latitude and high-altitude areas are more likely to develop MS (F = 8•99; p < 0•001). Prevalent comorbidities include hypertension (18•8%), diabetes (7•2%), stroke (14•7%), depression or anxiety (3•7%), and autoimmune disease (2•3%). Through 2016–2018, 104 adults and 2 children died, with a hospital mortality rate of 9•9 per 1,000 person-years.InterpretationFor the first time, we obtain the national incidence of MS as 0.055 in children and 0.288 in adults per 100,000 in China. The geographical distribution of MS incidence presented a north-south latitude gradient and a west-east altitude gradient.FundingNational Science Foundation of China (81801199, 91642205, and 81830038); Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing." @default.
- W3047890287 created "2020-08-13" @default.
- W3047890287 creator A5000875903 @default.
- W3047890287 creator A5065319077 @default.
- W3047890287 creator A5065999911 @default.
- W3047890287 creator A5080515125 @default.
- W3047890287 creator A5084148006 @default.
- W3047890287 creator A5084960189 @default.
- W3047890287 creator A5084968445 @default.
- W3047890287 creator A5086449718 @default.
- W3047890287 date "2020-08-01" @default.
- W3047890287 modified "2023-10-17" @default.
- W3047890287 title "Incidence of multiple sclerosis in China: A nationwide hospital-based study" @default.
- W3047890287 cites W1983459049 @default.
- W3047890287 cites W1991688760 @default.
- W3047890287 cites W1994216586 @default.
- W3047890287 cites W2004752476 @default.
- W3047890287 cites W2006791654 @default.
- W3047890287 cites W2023555055 @default.
- W3047890287 cites W2027285375 @default.
- W3047890287 cites W2100497914 @default.
- W3047890287 cites W2122545833 @default.
- W3047890287 cites W2142577589 @default.
- W3047890287 cites W2155477484 @default.
- W3047890287 cites W2273992279 @default.
- W3047890287 cites W2293924143 @default.
- W3047890287 cites W2339900693 @default.
- W3047890287 cites W2415795741 @default.
- W3047890287 cites W2418505775 @default.
- W3047890287 cites W2546810227 @default.
- W3047890287 cites W2560140067 @default.
- W3047890287 cites W2569387348 @default.
- W3047890287 cites W2597026225 @default.
- W3047890287 cites W2792140778 @default.
- W3047890287 cites W2887689171 @default.
- W3047890287 cites W2887726523 @default.
- W3047890287 cites W2911658427 @default.
- W3047890287 cites W2914200816 @default.
- W3047890287 cites W2914720734 @default.
- W3047890287 cites W2970972329 @default.
- W3047890287 cites W2990305591 @default.
- W3047890287 cites W3084009903 @default.
- W3047890287 doi "https://doi.org/10.1016/j.lanwpc.2020.100010" @default.
- W3047890287 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8315658" @default.
- W3047890287 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34327341" @default.
- W3047890287 hasPublicationYear "2020" @default.
- W3047890287 type Work @default.
- W3047890287 sameAs 3047890287 @default.
- W3047890287 citedByCount "25" @default.
- W3047890287 countsByYear W30478902872020 @default.
- W3047890287 countsByYear W30478902872021 @default.
- W3047890287 countsByYear W30478902872022 @default.
- W3047890287 countsByYear W30478902872023 @default.
- W3047890287 crossrefType "journal-article" @default.
- W3047890287 hasAuthorship W3047890287A5000875903 @default.
- W3047890287 hasAuthorship W3047890287A5065319077 @default.
- W3047890287 hasAuthorship W3047890287A5065999911 @default.
- W3047890287 hasAuthorship W3047890287A5080515125 @default.
- W3047890287 hasAuthorship W3047890287A5084148006 @default.
- W3047890287 hasAuthorship W3047890287A5084960189 @default.
- W3047890287 hasAuthorship W3047890287A5084968445 @default.
- W3047890287 hasAuthorship W3047890287A5086449718 @default.
- W3047890287 hasBestOaLocation W30478902871 @default.
- W3047890287 hasConcept C120665830 @default.
- W3047890287 hasConcept C121332964 @default.
- W3047890287 hasConcept C126322002 @default.
- W3047890287 hasConcept C134018914 @default.
- W3047890287 hasConcept C139719470 @default.
- W3047890287 hasConcept C162324750 @default.
- W3047890287 hasConcept C187212893 @default.
- W3047890287 hasConcept C195910791 @default.
- W3047890287 hasConcept C2776867660 @default.
- W3047890287 hasConcept C44249647 @default.
- W3047890287 hasConcept C555293320 @default.
- W3047890287 hasConcept C61511704 @default.
- W3047890287 hasConcept C71924100 @default.
- W3047890287 hasConceptScore W3047890287C120665830 @default.
- W3047890287 hasConceptScore W3047890287C121332964 @default.
- W3047890287 hasConceptScore W3047890287C126322002 @default.
- W3047890287 hasConceptScore W3047890287C134018914 @default.
- W3047890287 hasConceptScore W3047890287C139719470 @default.
- W3047890287 hasConceptScore W3047890287C162324750 @default.
- W3047890287 hasConceptScore W3047890287C187212893 @default.
- W3047890287 hasConceptScore W3047890287C195910791 @default.
- W3047890287 hasConceptScore W3047890287C2776867660 @default.
- W3047890287 hasConceptScore W3047890287C44249647 @default.
- W3047890287 hasConceptScore W3047890287C555293320 @default.
- W3047890287 hasConceptScore W3047890287C61511704 @default.
- W3047890287 hasConceptScore W3047890287C71924100 @default.
- W3047890287 hasLocation W30478902871 @default.
- W3047890287 hasLocation W30478902872 @default.
- W3047890287 hasLocation W30478902873 @default.
- W3047890287 hasOpenAccess W3047890287 @default.
- W3047890287 hasPrimaryLocation W30478902871 @default.
- W3047890287 hasRelatedWork W1563850031 @default.
- W3047890287 hasRelatedWork W1580426574 @default.
- W3047890287 hasRelatedWork W1967767793 @default.
- W3047890287 hasRelatedWork W2089620537 @default.