Matches in SemOpenAlex for { <https://semopenalex.org/work/W3047986670> ?p ?o ?g. }
- W3047986670 endingPage "101736" @default.
- W3047986670 startingPage "101736" @default.
- W3047986670 abstract "Abstract Flowers of Cannabis sativa contain many potentially therapeutic ingredients, including phytocannabinoids and terpenes. Consumption of cannabis requires drying and processing flowers which can potentially lead to accumulation of pathogens, including fungi and bacteria. In many countries, the level of pathogens in dried flowers is strictly regulated and thus, licensed cannabis cultivators irradiate dry flowers to decrease the chance of accumulation of pathogens. We have hypothesized that irradiation of flowers may change the level of active ingredients in flowers. We have tested the effect of gamma-radiation on the level of cannabinoids and terpenes in four varieties of cannabis. Plants were grown to maturity and flowers were harvested. One flower sample per variety was irradiated with 5 kGy using electron beam, while another sample was mock-treated. Cannabinoids were analyzed using HPLC and terpenes using GC-FID. Ethyl acetate was used to prepare extracts from two sets of flowers and extracts were tested for anti-proliferative capacity using methyl-thiazolyl-tetrazolium (MTT) assay on four different cancer cell lines, BJ-5ta, BT16, HCC1806 and IMR5. Solvent-based extraction of irradiated flowers showed slight increase in the total amount of solute. Irradiation of flowers resulted in the increased level of cannabinoids in the extract, more prominent in delta-9-tetrahydrocannabinol. There was also an increase in terpenes content in some cultivars. MTT assay showed that irradiation of flowers changed anti-cancer properties of three out of four tested extracts. Our experiments demonstrated that irradiation of flowers changes the amount of active ingredients in the extract and anti-cancer properties of such extracts." @default.
- W3047986670 created "2020-08-13" @default.
- W3047986670 creator A5015793767 @default.
- W3047986670 creator A5026505534 @default.
- W3047986670 creator A5042868572 @default.
- W3047986670 creator A5059737654 @default.
- W3047986670 creator A5069482413 @default.
- W3047986670 creator A5091803230 @default.
- W3047986670 date "2020-10-01" @default.
- W3047986670 modified "2023-09-30" @default.
- W3047986670 title "The effect of cannabis dry flower irradiation on the level of cannabinoids, terpenes and anti-cancer properties of the extracts" @default.
- W3047986670 cites W1485494169 @default.
- W3047986670 cites W1964860995 @default.
- W3047986670 cites W1972909482 @default.
- W3047986670 cites W1982433360 @default.
- W3047986670 cites W1984508655 @default.
- W3047986670 cites W1999066903 @default.
- W3047986670 cites W2003136679 @default.
- W3047986670 cites W2014329965 @default.
- W3047986670 cites W2021477108 @default.
- W3047986670 cites W2041112769 @default.
- W3047986670 cites W2043875371 @default.
- W3047986670 cites W2058918623 @default.
- W3047986670 cites W2064152975 @default.
- W3047986670 cites W2072864864 @default.
- W3047986670 cites W2074517497 @default.
- W3047986670 cites W2090852064 @default.
- W3047986670 cites W2103826070 @default.
- W3047986670 cites W2105175346 @default.
- W3047986670 cites W2148841660 @default.
- W3047986670 cites W2170023239 @default.
- W3047986670 cites W2326176611 @default.
- W3047986670 cites W2339133855 @default.
- W3047986670 cites W2466069397 @default.
- W3047986670 cites W2614812651 @default.
- W3047986670 cites W2729606178 @default.
- W3047986670 cites W2770675120 @default.
- W3047986670 cites W2780225807 @default.
- W3047986670 cites W2795881995 @default.
- W3047986670 cites W2811170405 @default.
- W3047986670 cites W2889483574 @default.
- W3047986670 cites W2889652386 @default.
- W3047986670 cites W2902255424 @default.
- W3047986670 cites W2905959020 @default.
- W3047986670 cites W2960172844 @default.
- W3047986670 cites W2969620302 @default.
- W3047986670 cites W3014324912 @default.
- W3047986670 cites W2607213612 @default.
- W3047986670 doi "https://doi.org/10.1016/j.bcab.2020.101736" @default.
- W3047986670 hasPublicationYear "2020" @default.
- W3047986670 type Work @default.
- W3047986670 sameAs 3047986670 @default.
- W3047986670 citedByCount "8" @default.
- W3047986670 countsByYear W30479866702021 @default.
- W3047986670 countsByYear W30479866702022 @default.
- W3047986670 countsByYear W30479866702023 @default.
- W3047986670 crossrefType "journal-article" @default.
- W3047986670 hasAuthorship W3047986670A5015793767 @default.
- W3047986670 hasAuthorship W3047986670A5026505534 @default.
- W3047986670 hasAuthorship W3047986670A5042868572 @default.
- W3047986670 hasAuthorship W3047986670A5059737654 @default.
- W3047986670 hasAuthorship W3047986670A5069482413 @default.
- W3047986670 hasAuthorship W3047986670A5091803230 @default.
- W3047986670 hasConcept C118552586 @default.
- W3047986670 hasConcept C121608353 @default.
- W3047986670 hasConcept C126322002 @default.
- W3047986670 hasConcept C185592680 @default.
- W3047986670 hasConcept C2777056318 @default.
- W3047986670 hasConcept C44937612 @default.
- W3047986670 hasConcept C55493867 @default.
- W3047986670 hasConcept C556039675 @default.
- W3047986670 hasConcept C71924100 @default.
- W3047986670 hasConceptScore W3047986670C118552586 @default.
- W3047986670 hasConceptScore W3047986670C121608353 @default.
- W3047986670 hasConceptScore W3047986670C126322002 @default.
- W3047986670 hasConceptScore W3047986670C185592680 @default.
- W3047986670 hasConceptScore W3047986670C2777056318 @default.
- W3047986670 hasConceptScore W3047986670C44937612 @default.
- W3047986670 hasConceptScore W3047986670C55493867 @default.
- W3047986670 hasConceptScore W3047986670C556039675 @default.
- W3047986670 hasConceptScore W3047986670C71924100 @default.
- W3047986670 hasFunder F4320319949 @default.
- W3047986670 hasFunder F4320334593 @default.
- W3047986670 hasLocation W30479866701 @default.
- W3047986670 hasOpenAccess W3047986670 @default.
- W3047986670 hasPrimaryLocation W30479866701 @default.
- W3047986670 hasRelatedWork W2327434034 @default.
- W3047986670 hasRelatedWork W2370119705 @default.
- W3047986670 hasRelatedWork W2605440595 @default.
- W3047986670 hasRelatedWork W2949901858 @default.
- W3047986670 hasRelatedWork W3038535682 @default.
- W3047986670 hasRelatedWork W3112625723 @default.
- W3047986670 hasRelatedWork W3135476444 @default.
- W3047986670 hasRelatedWork W4214622773 @default.
- W3047986670 hasRelatedWork W4311724840 @default.
- W3047986670 hasRelatedWork W2510963587 @default.
- W3047986670 hasVolume "29" @default.
- W3047986670 isParatext "false" @default.