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- W3048004441 endingPage "100041" @default.
- W3048004441 startingPage "100041" @default.
- W3048004441 abstract "Gastrointestinal (GI) cancers represent a major public health problem worldwide. Due to the late detection and high heterogeneity of GI cancers, traditional treatments, including surgery, radiotherapy, chemotherapy, and targeted therapy, have shown limited effects, and the overall prognosis of these patients remains poor. Recently, immunotherapy, involving programmed cell death-1 (PD-1) and its ligand (PD-L1), has shown promising efficacy in several solid cancers and seems to have become a potential treatment option for GI cancers This review focuses on data on the development of immunotherapy-based clinical trials in esophageal cancer, gastric cancer, and colorectal cancer. The predictive biomarkers and combination strategies in clinical trials and translational medicine are also discussed. Finally, prospects for immunotherapy in the treatment of GI cancers are described. Although only a small proportion of patients with GI cancers respond to PD-1/PD-L1 blockade, we strongly believe that precision immunotherapy might improve the overall survival of many more GI cancer patients in the future." @default.
- W3048004441 created "2020-08-13" @default.
- W3048004441 creator A5014406637 @default.
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- W3048004441 date "2020-08-01" @default.
- W3048004441 modified "2023-10-09" @default.
- W3048004441 title "Current Status and Future Perspective of Immunotherapy in Gastrointestinal Cancers" @default.
- W3048004441 cites W1590798843 @default.
- W3048004441 cites W1938515409 @default.
- W3048004441 cites W1940241680 @default.
- W3048004441 cites W1965215390 @default.
- W3048004441 cites W1980081703 @default.
- W3048004441 cites W1980207416 @default.
- W3048004441 cites W2000121076 @default.
- W3048004441 cites W2017209592 @default.
- W3048004441 cites W2028311581 @default.
- W3048004441 cites W2042576421 @default.
- W3048004441 cites W2066671159 @default.
- W3048004441 cites W2071255079 @default.
- W3048004441 cites W2094945699 @default.
- W3048004441 cites W2100928937 @default.
- W3048004441 cites W2103118255 @default.
- W3048004441 cites W2103675014 @default.
- W3048004441 cites W2104885590 @default.
- W3048004441 cites W2107429737 @default.
- W3048004441 cites W2107863654 @default.
- W3048004441 cites W2113404235 @default.
- W3048004441 cites W2114101532 @default.
- W3048004441 cites W2114903025 @default.
- W3048004441 cites W2115975916 @default.
- W3048004441 cites W2116376943 @default.
- W3048004441 cites W2121847974 @default.
- W3048004441 cites W2125270092 @default.
- W3048004441 cites W2126547130 @default.
- W3048004441 cites W2127737941 @default.
- W3048004441 cites W2132923173 @default.
- W3048004441 cites W2159064822 @default.
- W3048004441 cites W2165456770 @default.
- W3048004441 cites W2169579205 @default.
- W3048004441 cites W2185075416 @default.
- W3048004441 cites W2257916459 @default.
- W3048004441 cites W2270932386 @default.
- W3048004441 cites W2272984102 @default.
- W3048004441 cites W2291007149 @default.
- W3048004441 cites W2299181842 @default.
- W3048004441 cites W2347070489 @default.
- W3048004441 cites W2397854274 @default.
- W3048004441 cites W2427476638 @default.
- W3048004441 cites W2521503673 @default.
- W3048004441 cites W2554479252 @default.
- W3048004441 cites W2560367415 @default.
- W3048004441 cites W2597946622 @default.
- W3048004441 cites W2606495925 @default.
- W3048004441 cites W2616637874 @default.
- W3048004441 cites W2622499649 @default.
- W3048004441 cites W2625777803 @default.
- W3048004441 cites W2655262992 @default.
- W3048004441 cites W2739132742 @default.
- W3048004441 cites W2763064222 @default.
- W3048004441 cites W2765314233 @default.
- W3048004441 cites W2767857925 @default.
- W3048004441 cites W2769896725 @default.
- W3048004441 cites W2776526327 @default.
- W3048004441 cites W2783494975 @default.
- W3048004441 cites W2784283849 @default.
- W3048004441 cites W2784868445 @default.
- W3048004441 cites W2790175021 @default.
- W3048004441 cites W2793364080 @default.
- W3048004441 cites W2800948756 @default.
- W3048004441 cites W2806614796 @default.
- W3048004441 cites W2808750176 @default.
- W3048004441 cites W2808944387 @default.
- W3048004441 cites W2810879984 @default.
- W3048004441 cites W2883552436 @default.
- W3048004441 cites W2884397450 @default.
- W3048004441 cites W2885429746 @default.
- W3048004441 cites W2887629404 @default.
- W3048004441 cites W2888044930 @default.
- W3048004441 cites W2888572922 @default.
- W3048004441 cites W2889459498 @default.
- W3048004441 cites W2889646458 @default.
- W3048004441 cites W2890994111 @default.
- W3048004441 cites W2896134447 @default.
- W3048004441 cites W2897815318 @default.
- W3048004441 cites W2898246178 @default.
- W3048004441 cites W2906166963 @default.
- W3048004441 cites W2906436263 @default.
- W3048004441 cites W2909679049 @default.
- W3048004441 cites W2912167213 @default.
- W3048004441 cites W2912271356 @default.
- W3048004441 cites W2912943897 @default.
- W3048004441 cites W2913400417 @default.