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• W3048134454 endingPage "89" @default.
• W3048134454 startingPage "89" @default.
• W3048134454 abstract "Peroxides present in oral healthcare products generally exert favourable protective activities against the development and progression of tooth decay, plaque, gingivitis, and halitosis, etc. However, despite the high level of research focus on hydrogen and carbamide peroxides as therapeutically active (and tooth-whitening) agents, to date the use of alternative chemical forms of peroxides such as peroxoborates for these purposes has received only scant attention. Intriguingly, peroxoborate and its esters with polyols, such as glycerol, have a very diverse chemistry/biochemistry in aqueous solution, for which there is an increasing amount of evidence that it remains distinctive from that of hydrogen peroxide; such properties include self-associative and hydrolytic equilibria, and their abilities to participate in electrophile- or nucleophile-scavenging, metal ion-complexing, redox and free radical reactions, for example. Therefore, the purpose of this detailed commentary is to evaluate both differences and similarities between the molecular/biomolecular reactivities of peroxoborate species and hydrogen peroxide in vitro, ex-vivo and in vivo. It encompasses brief sectional accounts regarding the molecular heterogeneity of peroxoborates, the release of bioactive agents therefrom, and their oxidative attack on oral cavity biomolecules (the nucleophilic or electrophilic character of these oxidations are discussed). Further areas explored are the abilities of borates and peroxoborates to enhance the solubility of iron ions in aqueous solution, their involvements in free radical biochemistry (particularly the complexation of oxygen radical-promoting transition metal ions by, and antioxidant properties of, peroxoborate-polyol ester adducts), and the specific inhibition of protease enzymes. Further aspects focus on the tooth-whitening, oral malodor neutralizing, and potential mutagenic and genotoxic properties of peroxoborates, along with possible mechanisms for these processes. The abilities of peroxoborates, and peroxides in general, to modulate the activities of inflammatory mediators and vitamins, antioxidant or otherwise, are also explored." @default.
• W3048134454 created "2020-08-13" @default.
• W3048134454 creator A5004766052 @default.
• W3048134454 creator A5014837930 @default.
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• W3048134454 creator A5065840120 @default.
• W3048134454 creator A5067900647 @default.
• W3048134454 creator A5076037101 @default.
• W3048134454 date "2020-08-07" @default.
• W3048134454 modified "2023-09-26" @default.
• W3048134454 title "Potential Advantages of Peroxoborates and Their Ester Adducts Over Hydrogen Peroxide as Therapeutic Agents in Oral Healthcare Products: Chemical/Biochemical Reactivity Considerations In Vitro, Ex Vivo And In Vivo" @default.
• W3048134454 cites W103834307 @default.
• W3048134454 cites W108923488 @default.
• W3048134454 cites W1496473441 @default.
• W3048134454 cites W1553571725 @default.
• W3048134454 cites W1619383772 @default.
• W3048134454 cites W1963874760 @default.
• W3048134454 cites W1965855168 @default.
• W3048134454 cites W1966697756 @default.
• W3048134454 cites W1968157065 @default.
• W3048134454 cites W1968243295 @default.
• W3048134454 cites W1968980895 @default.
• W3048134454 cites W1976067575 @default.
• W3048134454 cites W1979322538 @default.
• W3048134454 cites W1979424755 @default.
• W3048134454 cites W1982424628 @default.
• W3048134454 cites W1983039689 @default.
• W3048134454 cites W1988091138 @default.
• W3048134454 cites W1988620917 @default.
• W3048134454 cites W1989006813 @default.
• W3048134454 cites W1990540971 @default.
• W3048134454 cites W1991633494 @default.
• W3048134454 cites W1993717592 @default.
• W3048134454 cites W1993864037 @default.
• W3048134454 cites W1994115675 @default.
• W3048134454 cites W1995553272 @default.
• W3048134454 cites W1996099843 @default.
• W3048134454 cites W1997872757 @default.
• W3048134454 cites W1999778493 @default.
• W3048134454 cites W2001055727 @default.
• W3048134454 cites W2002038377 @default.
• W3048134454 cites W2003487925 @default.
• W3048134454 cites W2004208153 @default.
• W3048134454 cites W2006654333 @default.
• W3048134454 cites W2007074029 @default.
• W3048134454 cites W2010025510 @default.
• W3048134454 cites W2010308955 @default.
• W3048134454 cites W2011412628 @default.
• W3048134454 cites W2014223976 @default.
• W3048134454 cites W2014862947 @default.
• W3048134454 cites W2015213693 @default.
• W3048134454 cites W2015745267 @default.
• W3048134454 cites W2015823573 @default.
• W3048134454 cites W2024220305 @default.
• W3048134454 cites W2024657067 @default.
• W3048134454 cites W2029496236 @default.
• W3048134454 cites W2029906694 @default.
• W3048134454 cites W2032786833 @default.
• W3048134454 cites W2037732096 @default.
• W3048134454 cites W2038647020 @default.
• W3048134454 cites W2040643845 @default.
• W3048134454 cites W2045558912 @default.
• W3048134454 cites W2046940666 @default.
• W3048134454 cites W2047182273 @default.
• W3048134454 cites W2048339310 @default.
• W3048134454 cites W2053715596 @default.
• W3048134454 cites W2058710854 @default.
• W3048134454 cites W2060876438 @default.
• W3048134454 cites W2062019033 @default.
• W3048134454 cites W2062747983 @default.
• W3048134454 cites W2063918376 @default.
• W3048134454 cites W2065632870 @default.
• W3048134454 cites W2067948663 @default.
• W3048134454 cites W2068470056 @default.
• W3048134454 cites W2068805838 @default.
• W3048134454 cites W2071299413 @default.
• W3048134454 cites W2071548430 @default.
• W3048134454 cites W2072618519 @default.
• W3048134454 cites W2073283167 @default.
• W3048134454 cites W2074546168 @default.
• W3048134454 cites W2075345942 @default.
• W3048134454 cites W2076062506 @default.
• W3048134454 cites W2077400653 @default.
• W3048134454 cites W2080084300 @default.
• W3048134454 cites W2081016731 @default.
• W3048134454 cites W2082016914 @default.
• W3048134454 cites W2082726030 @default.
• W3048134454 cites W2085089224 @default.
• W3048134454 cites W2085593701 @default.
• W3048134454 cites W2087313381 @default.
• W3048134454 cites W2088740296 @default.
• W3048134454 cites W2089445171 @default.
• W3048134454 cites W2094425385 @default.
• W3048134454 cites W2095325281 @default.
• W3048134454 cites W2097029812 @default.

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